CH618183A5 - - Google Patents

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Publication number
CH618183A5
CH618183A5 CH1580574A CH1580574A CH618183A5 CH 618183 A5 CH618183 A5 CH 618183A5 CH 1580574 A CH1580574 A CH 1580574A CH 1580574 A CH1580574 A CH 1580574A CH 618183 A5 CH618183 A5 CH 618183A5
Authority
CH
Switzerland
Prior art keywords
homo
acid
carbon
hydrogen
hydroxy
Prior art date
Application number
CH1580574A
Other languages
German (de)
English (en)
Inventor
Ulrich Dr Kerb
Rudolf Prof Dr Wiechert
Klaus Dr Kieslich
Karl Dr Petzoldt
Helmut Dr Wachtel
Dieter Dr Palenschat
Reinhard Dr Horowski
Gert Dr Paschelke
Wolfgang Dr Kehr
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2360443A external-priority patent/DE2360443A1/de
Priority claimed from DE19742445161 external-priority patent/DE2445161A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of CH618183A5 publication Critical patent/CH618183A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
CH1580574A 1973-11-30 1974-11-28 CH618183A5 (en:Method)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2360443A DE2360443A1 (de) 1973-11-30 1973-11-30 D-homo-20-ketopregnane
DE19742445161 DE2445161A1 (de) 1974-09-19 1974-09-19 D-homo-20-ketopregnane ii

Publications (1)

Publication Number Publication Date
CH618183A5 true CH618183A5 (en:Method) 1980-07-15

Family

ID=25766200

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1580574A CH618183A5 (en:Method) 1973-11-30 1974-11-28

Country Status (14)

Country Link
US (1) US4045574A (en:Method)
JP (1) JPS5084561A (en:Method)
AT (1) AT347611B (en:Method)
CA (1) CA1030522A (en:Method)
CH (1) CH618183A5 (en:Method)
DD (1) DD115659A5 (en:Method)
DK (1) DK134348C (en:Method)
ES (1) ES432106A1 (en:Method)
FR (1) FR2253512B1 (en:Method)
GB (1) GB1494097A (en:Method)
IE (1) IE40423B1 (en:Method)
IL (1) IL46153A (en:Method)
NL (1) NL7415577A (en:Method)
SE (1) SE408426B (en:Method)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879316A (en) * 1987-02-26 1989-11-07 The University Of Tennessee Research Corporation Interpenetrating polymer network ion exchange membranes and method for preparing same
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
ES2271636T3 (es) * 2002-08-16 2007-04-16 PHARMACIA & UPJOHN COMPANY LLC Intermediarios de 5 androsten-3-ol esteroides y procedimientos para su preparacion.
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
MX395023B (es) 2013-04-17 2025-03-24 Sage Therapeutics Inc Esteroides c21-n-pirazolilo 19-nor c3,3-disustituidos y metodos de uso de los mismos.
PT2986624T (pt) 2013-04-17 2020-07-07 Sage Therapeutics Inc Esteroides neuroativos 19-nor para métodos de tratamento
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
RU2754534C2 (ru) 2013-07-19 2021-09-03 Сейдж Терапьютикс, Инк. Нейроактивные стероиды, композиции и их использование
BR112016003862B1 (pt) 2013-08-23 2022-09-06 Sage Therapeutics, Inc Compostos esteroides neuroativos, suas composições e seus usos
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US20170233433A1 (en) 2014-10-16 2017-08-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
CN107404877A (zh) 2014-10-16 2017-11-28 萨奇治疗股份有限公司 靶向cns 障碍的组合物和方法
HRP20200840T1 (hr) 2014-11-27 2020-11-13 Sage Therapeutics, Inc. Pripravci i postupci za liječenje poremećaja cns-a
HUE054092T2 (hu) 2015-01-26 2021-08-30 Sage Therapeutics Inc Központi idegrendszeri zavarok kezelésére szolgáló kompozíciók és eljárások
US10329320B2 (en) 2015-02-20 2019-06-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CA3030420A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
EP4302764A3 (en) 2016-07-11 2024-06-26 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
CN118772223A (zh) * 2017-12-22 2024-10-15 萨奇治疗股份有限公司 治疗中枢神经系统疾病的组合物和方法
CA3120872A1 (en) 2018-12-05 2020-06-11 Sage Therapeutics, Inc. Neuroactive steroids and their methods of use
JOP20210293A1 (ar) 2019-05-31 2023-01-30 Sage Therapeutics Inc ستيرويدات ذات فعالية عصبية وتركيبات منها
CA3144701A1 (en) * 2019-06-27 2020-12-30 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
AU2020304679A1 (en) * 2019-06-27 2022-01-20 Sage Therapeutics, Inc. Compounds for treating CNS disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860158A (en) * 1954-10-18 1958-11-11 Sterling Drug Inc Compounds of the perhydrochrysene series and preparation thereof
US3686223A (en) * 1968-12-26 1972-08-22 Sterling Drug Inc D-homoestratrienes
US3833621A (en) * 1972-03-20 1974-09-03 Richardson Merrell Inc 3-keto-7(alpha,beta)-loweralkyl-delta5 steroids and process for preparing same

Also Published As

Publication number Publication date
ATA950774A (de) 1978-05-15
NL7415577A (nl) 1975-06-03
DD115659A5 (en:Method) 1975-10-12
GB1494097A (en) 1977-12-07
DK604174A (en:Method) 1975-07-28
IL46153A0 (en) 1975-02-10
ES432106A1 (es) 1976-11-01
IE40423L (en) 1975-05-30
CA1030522A (en) 1978-05-02
AT347611B (de) 1979-01-10
DK134348C (da) 1977-03-21
IL46153A (en) 1979-01-31
JPS5084561A (en:Method) 1975-07-08
FR2253512B1 (en:Method) 1978-02-03
SE408426B (sv) 1979-06-11
DK134348B (da) 1976-10-25
AU7586774A (en) 1976-06-03
FR2253512A1 (en:Method) 1975-07-04
US4045574A (en) 1977-08-30
SE7414960L (en:Method) 1975-06-02
IE40423B1 (en) 1979-05-23

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