CH616165A5 - Process for converting a 3-acyloxymethylceph-3-em-4-carboxylic acid into a 3-hydroxymethylceph-3-em-4-carboxylic acid. - Google Patents

Process for converting a 3-acyloxymethylceph-3-em-4-carboxylic acid into a 3-hydroxymethylceph-3-em-4-carboxylic acid. Download PDF

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Publication number
CH616165A5
CH616165A5 CH1446275A CH1446275A CH616165A5 CH 616165 A5 CH616165 A5 CH 616165A5 CH 1446275 A CH1446275 A CH 1446275A CH 1446275 A CH1446275 A CH 1446275A CH 616165 A5 CH616165 A5 CH 616165A5
Authority
CH
Switzerland
Prior art keywords
group
carboxylic acid
ceph
esterase
formula
Prior art date
Application number
CH1446275A
Other languages
German (de)
English (en)
Inventor
Alan Smith
Ronald William Larner
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of CH616165A5 publication Critical patent/CH616165A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
CH1446275A 1974-11-08 1975-11-07 Process for converting a 3-acyloxymethylceph-3-em-4-carboxylic acid into a 3-hydroxymethylceph-3-em-4-carboxylic acid. CH616165A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB48522/74A GB1531212A (en) 1974-11-08 1974-11-08 Enzymatic hydrolysis of 3-acyloxymethylceph-3-em-4-carboxylic acids or salts thereof

Publications (1)

Publication Number Publication Date
CH616165A5 true CH616165A5 (en) 1980-03-14

Family

ID=10448929

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1446275A CH616165A5 (en) 1974-11-08 1975-11-07 Process for converting a 3-acyloxymethylceph-3-em-4-carboxylic acid into a 3-hydroxymethylceph-3-em-4-carboxylic acid.

Country Status (8)

Country Link
JP (2) JPS5646839B2 (enrdf_load_stackoverflow)
AU (1) AU500894B2 (enrdf_load_stackoverflow)
CH (1) CH616165A5 (enrdf_load_stackoverflow)
DE (1) DE2550110A1 (enrdf_load_stackoverflow)
FR (1) FR2290444A1 (enrdf_load_stackoverflow)
GB (1) GB1531212A (enrdf_load_stackoverflow)
NL (1) NL177422C (enrdf_load_stackoverflow)
ZA (1) ZA757003B (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT378003B (de) * 1979-07-19 1985-06-10 Glaxo Group Ltd Verfahren zur herstellung von desactylcephalosporin c
US4414328A (en) 1980-07-21 1983-11-08 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of deacetylcephalosporin C
US5466787A (en) * 1993-11-15 1995-11-14 Bristol-Myers Squibb Company Process for preparing AZT
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins
CA2263801A1 (en) * 1996-09-18 1998-03-26 Bristol-Myers Squibb Company Cephalosporin esterase gene from rhodosporidium toruloides

Also Published As

Publication number Publication date
GB1531212A (en) 1978-11-08
NL177422B (nl) 1985-04-16
AU8635775A (en) 1977-05-12
AU500894B2 (en) 1979-06-07
NL177422C (nl) 1985-09-16
FR2290444B1 (enrdf_load_stackoverflow) 1979-03-23
JPS6111600B2 (enrdf_load_stackoverflow) 1986-04-03
DE2550110A1 (de) 1976-05-13
FR2290444A1 (fr) 1976-06-04
JPS5646839B2 (enrdf_load_stackoverflow) 1981-11-05
ZA757003B (en) 1976-10-27
JPS56169595A (en) 1981-12-26
JPS5176489A (enrdf_load_stackoverflow) 1976-07-02
NL7513065A (nl) 1976-05-11

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Owner name: GLAXO OPERATIONS UK LIMITED

PL Patent ceased
PL Patent ceased