CH613687A5 - - Google Patents

Info

Publication number
CH613687A5
CH613687A5 CH1035976A CH1035976A CH613687A5 CH 613687 A5 CH613687 A5 CH 613687A5 CH 1035976 A CH1035976 A CH 1035976A CH 1035976 A CH1035976 A CH 1035976A CH 613687 A5 CH613687 A5 CH 613687A5
Authority
CH
Switzerland
Application number
CH1035976A
Inventor
Tadashi Takemoto
Fusayoshi Kakizaki
Yasuo Ariyoshi
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of CH613687A5 publication Critical patent/CH613687A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/122—Hydrolysis with acids different from HF

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1035976A 1975-08-14 1976-08-13 CH613687A5 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50098817A JPS5223001A (en) 1975-08-14 1975-08-14 Process for elimination of formyl group

Publications (1)

Publication Number Publication Date
CH613687A5 true CH613687A5 (xx) 1979-10-15

Family

ID=14229861

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1035976A CH613687A5 (xx) 1975-08-14 1976-08-13

Country Status (9)

Country Link
US (1) US4071511A (xx)
JP (1) JPS5223001A (xx)
AU (1) AU499510B2 (xx)
CA (1) CA1075680A (xx)
CH (1) CH613687A5 (xx)
DE (1) DE2635948C2 (xx)
FR (1) FR2320934A1 (xx)
GB (1) GB1497248A (xx)
NL (1) NL7608965A (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX4704E (es) * 1976-12-27 1982-08-04 Monsanto Co Procedimiento mejorado para la preparacion de ester metilico de alfa-l-aspartil-l-fenilalanina
JPS57125891U (xx) * 1981-01-31 1982-08-05
JPS57131746A (en) * 1981-02-10 1982-08-14 Ajinomoto Co Inc Removal of n-formyl group
IE810577L (en) * 1983-05-31 1982-09-16 Prendergast Angela Apparatus for fermentation
IT1194795B (it) * 1981-05-13 1988-09-28 Pierrel Spa Procedimento per la eliminazione del gruppo n-formile da peptidi n-formilati e da esteri di peptidi n-formilati
JPS5821687U (ja) * 1981-08-03 1983-02-10 新日軽株式会社 建具
JPH03169894A (ja) * 1982-04-22 1991-07-23 Ajinomoto Co Inc α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルまたはその塩酸塩の製法
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
GB8321802D0 (en) * 1983-08-12 1983-09-14 Erba Farmitalia Aspartame synthesis
JPH07636B2 (ja) * 1984-12-17 1995-01-11 三井東圧化学株式会社 Ｎ−ホルミル−α−アスパルチルフエニルアラニンの製造法
CA1277098C (en) * 1984-12-27 1990-11-27 Mitsui Toatsu Chemicals, Inc. Preparation process of -l-aspartyl-l-phenylalanine methyl ester
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
IT1190395B (it) * 1985-09-30 1988-02-16 Lark Spa Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido
JPH0680075B2 (ja) * 1985-12-24 1994-10-12 味の素株式会社 Ｎ―ホルミル―α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの製造法
DE3780585T2 (de) * 1986-12-05 1993-03-18 Mitsui Toatsu Chemicals Herstellung von alpha-l-aspartyl-l-phenylalanin-methylester oder deren hydrohalide.
JPH0832719B2 (ja) * 1986-12-19 1996-03-29 三井東圧化学株式会社 吸湿性の小さいα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法
IT1270852B (it) * 1992-08-27 1997-05-13 Miwon Co Ltd Procedimento per la produzione dell'estere metilico di alfa-l-aspartil-l-fenilalanina.
CA2447470A1 (en) * 2001-05-09 2002-11-14 Newbiotics, Inc. Peptide deformylase activated prodrugs
CA2482029A1 (en) * 2002-04-18 2003-10-30 Maria V. Sergeeva Peptide deformylase activated prodrugs
EP1585751A4 (en) * 2002-11-14 2008-08-13 Celmed Oncology Usa Inc PEPTIDE DEFORMYLASE-ACTIVATED PRODRUGS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2053188C3 (de) * 1970-10-29 1979-11-22 Ajinomoto Co. Inc., Tokio Verfahren zur Herstellung von Niederalkylestern des a -L-Asparagyl- L-phenylalanins
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5823380B2 (ja) * 1974-12-05 1983-05-14 味の素株式会社 ホルミルキノ ダツリホウ

Also Published As

Publication number Publication date
US4071511A (en) 1978-01-31
FR2320934A1 (fr) 1977-03-11
DE2635948A1 (de) 1977-03-03
AU1663676A (en) 1978-02-09
AU499510B2 (en) 1979-04-26
CA1075680A (en) 1980-04-15
JPS5223001A (en) 1977-02-21
FR2320934B1 (xx) 1980-05-23
DE2635948C2 (de) 1985-11-14
JPS5726588B2 (xx) 1982-06-05
GB1497248A (en) 1978-01-05
NL7608965A (nl) 1977-02-16

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Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: THE NUTRASWEET COMPANY

PL Patent ceased