US4780409A
(en)
*
|
1985-05-02 |
1988-10-25 |
Genetic Systems Corporation |
Thermally induced phase separation immunoassay
|
US4766106A
(en)
*
|
1985-06-26 |
1988-08-23 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polymer conjugation
|
US5206344A
(en)
*
|
1985-06-26 |
1993-04-27 |
Cetus Oncology Corporation |
Interleukin-2 muteins and polymer conjugation thereof
|
US4959305A
(en)
*
|
1986-06-18 |
1990-09-25 |
Miles Inc. |
Reversible immobilization of assay reagents in a multizone test device
|
DE3786511T2
(de)
*
|
1986-09-17 |
1994-01-13 |
Beecham Group Plc |
Immobilisiertes Enzympräparat und seine Verwendung.
|
US4894226A
(en)
*
|
1986-11-14 |
1990-01-16 |
Cetus Corporation |
Solubilization of proteins for pharmaceutical compositions using polyproline conjugation
|
US4847325A
(en)
*
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
US5162430A
(en)
*
|
1988-11-21 |
1992-11-10 |
Collagen Corporation |
Collagen-polymer conjugates
|
US5510418A
(en)
*
|
1988-11-21 |
1996-04-23 |
Collagen Corporation |
Glycosaminoglycan-synthetic polymer conjugates
|
US5565519A
(en)
*
|
1988-11-21 |
1996-10-15 |
Collagen Corporation |
Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
|
US5306500A
(en)
*
|
1988-11-21 |
1994-04-26 |
Collagen Corporation |
Method of augmenting tissue with collagen-polymer conjugates
|
US5166322A
(en)
*
|
1989-04-21 |
1992-11-24 |
Genetics Institute |
Cysteine added variants of interleukin-3 and chemical modifications thereof
|
WO1993020838A1
(en)
*
|
1992-04-20 |
1993-10-28 |
Rufeld, Inc. |
Method and compositions for treatment of pyonecrotic processes
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
ATE330644T1
(de)
*
|
1995-12-18 |
2006-07-15 |
Angiotech Biomaterials Corp |
Vernetzten polymerisatmassen und verfahren für ihre verwendung
|
US6458889B1
(en)
|
1995-12-18 |
2002-10-01 |
Cohesion Technologies, Inc. |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
|
US7883693B2
(en)
*
|
1995-12-18 |
2011-02-08 |
Angiodevice International Gmbh |
Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
|
US6833408B2
(en)
*
|
1995-12-18 |
2004-12-21 |
Cohesion Technologies, Inc. |
Methods for tissue repair using adhesive materials
|
WO1997024421A2
(en)
*
|
1995-12-29 |
1997-07-10 |
The Procter & Gamble Company |
Detergent compositions comprising immobilized enzymes
|
AU5104098A
(en)
*
|
1996-11-14 |
1998-06-03 |
Polymer Technology Corporation |
Use of water soluble enzyme-polymer conjugates for cleaning contact lenses
|
BRPI9915542C1
(pt)
*
|
1998-10-16 |
2021-05-25 |
Biogen Idec Inc |
composição compreendendo um interferon-beta-1a glicosilado, composição farmacêutica compreendendo a mesma e processo in vitro de prolongar a atividade do interferon-beta-1a em um sistema in vitro
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7795210B2
(en)
*
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
EP1578771B1
(en)
|
2001-10-10 |
2013-03-06 |
Novo Nordisk A/S |
Remodeling and glycoconjugation of peptides
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
MXPA04012496A
(es)
*
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
CA2511486A1
(en)
*
|
2002-12-30 |
2004-07-22 |
Angiotech International Ag |
Tissue reactive compounds and compositions and uses thereof
|
EP1594459B1
(en)
*
|
2002-12-30 |
2010-02-17 |
Angiotech International Ag |
Drug delivery from rapid gelling polymer composition
|
MXPA05009726A
(es)
*
|
2003-03-14 |
2005-11-04 |
Neose Technologies Inc |
Polimeros ramificados, solubles en agua y sus conjugados.
|
US20070026485A1
(en)
|
2003-04-09 |
2007-02-01 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
EP1613261A4
(en)
*
|
2003-04-09 |
2011-01-26 |
Novo Nordisk As |
INTRA-CELLULAR FORMATION OF PEPTIDE CONJUGATES
|
AU2004240553A1
(en)
|
2003-05-09 |
2004-12-02 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
US7842661B2
(en)
*
|
2003-11-24 |
2010-11-30 |
Novo Nordisk A/S |
Glycopegylated erythropoietin formulations
|
US8633157B2
(en)
*
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
WO2005051327A2
(en)
*
|
2003-11-24 |
2005-06-09 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US20080305992A1
(en)
*
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
US20070254836A1
(en)
*
|
2003-12-03 |
2007-11-01 |
Defrees Shawn |
Glycopegylated Granulocyte Colony Stimulating Factor
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
ES2560657T3
(es)
*
|
2004-01-08 |
2016-02-22 |
Ratiopharm Gmbh |
Glicosilación con unión en O de péptidos G-CSF
|
JP4124361B2
(ja)
*
|
2004-02-16 |
2008-07-23 |
農工大ティー・エル・オー株式会社 |
化学物質の分離方法
|
BRPI0510477B1
(pt)
|
2004-04-28 |
2023-01-17 |
Angiotech Biomaterials Corporation |
Método para formar um gel e dispositivo para uso em aplicações médicas
|
WO2005111225A1
(en)
*
|
2004-05-04 |
2005-11-24 |
Novo Nordisk Health Care Ag |
O-linked glycoforms of polypeptides and method to manufacture them
|
WO2006010143A2
(en)
|
2004-07-13 |
2006-01-26 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
|
US8268967B2
(en)
*
|
2004-09-10 |
2012-09-18 |
Novo Nordisk A/S |
Glycopegylated interferon α
|
WO2006034128A2
(en)
|
2004-09-17 |
2006-03-30 |
Angiotech Biomaterials Corporation |
Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use
|
WO2006035057A1
(en)
*
|
2004-09-29 |
2006-04-06 |
Novo Nordisk Health Care Ag |
Modified proteins
|
DK2586456T3
(en)
|
2004-10-29 |
2016-03-21 |
Ratiopharm Gmbh |
Conversion and glycopegylation of fibroblast growth factor (FGF)
|
JP2008526864A
(ja)
*
|
2005-01-06 |
2008-07-24 |
ネオス テクノロジーズ インコーポレイテッド |
糖断片を用いる糖結合
|
CA2593682C
(en)
|
2005-01-10 |
2016-03-22 |
Neose Technologies, Inc. |
Glycopegylated granulocyte colony stimulating factor
|
JP2008538181A
(ja)
*
|
2005-03-30 |
2008-10-16 |
ネオス テクノロジーズ インコーポレイテッド |
昆虫細胞系において増殖させたペプチドを生産するための製造方法
|
WO2006121569A2
(en)
*
|
2005-04-08 |
2006-11-16 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
JP5216580B2
(ja)
*
|
2005-05-25 |
2013-06-19 |
ノヴォ ノルディスク アー/エス |
グリコペグ化第ix因子
|
US20070105755A1
(en)
*
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
MX2008002395A
(es)
*
|
2005-08-19 |
2008-03-18 |
Neose Technologies Inc |
Factor vii y factor viia glicopegilados.
|
US20090048440A1
(en)
*
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
US20080242607A1
(en)
*
|
2006-07-21 |
2008-10-02 |
Neose Technologies, Inc. |
Glycosylation of peptides via o-linked glycosylation sequences
|
EP2054521A4
(en)
*
|
2006-10-03 |
2012-12-19 |
Novo Nordisk As |
PROCESS FOR CLEANING POLYPEPTIDE CONJUGATES
|
RU2460543C2
(ru)
*
|
2006-10-04 |
2012-09-10 |
Ново Нордиск А/С |
Глицерин-связанные пэгилированные сахара и гликопептиды
|
US20080207487A1
(en)
*
|
2006-11-02 |
2008-08-28 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
PT2144923E
(pt)
|
2007-04-03 |
2013-05-15 |
Biogenerix Ag |
Métodos de tratamento com g-csf glicopeguilado
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
CN101778937A
(zh)
*
|
2007-06-04 |
2010-07-14 |
诺和诺德公司 |
使用n-乙酰葡糖胺转移酶的o-联糖基化
|
WO2008154639A2
(en)
*
|
2007-06-12 |
2008-12-18 |
Neose Technologies, Inc. |
Improved process for the production of nucleotide sugars
|
EP2578235A3
(en)
|
2007-08-27 |
2013-08-28 |
BioGeneriX AG |
Liquid formulation of G-CSF conjugate
|
US8207112B2
(en)
*
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
ES2796623T3
(es)
*
|
2007-09-28 |
2020-11-27 |
Portola Pharm Inc |
Antídotos para inhibidores del factor Xa y procedimientos de uso de los mismos
|
EP2245056B1
(en)
|
2008-01-22 |
2015-03-11 |
Araim Pharmaceuticals, Inc. |
Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage
|
RU2573587C2
(ru)
|
2008-02-27 |
2016-01-20 |
Ново Нордиск А/С |
Конъюгированные молекулы фактора viii
|
EP2672260A1
(en)
|
2008-05-13 |
2013-12-11 |
Advanced Liquid Logic, Inc. |
Droplet actuator devices, systems and methods
|
GB2516388A
(en)
|
2012-04-16 |
2015-01-21 |
Cantab Biopharmaceuticals Patents Ltd |
Optimised subcutaneous therapeutic agents
|
CN109310741A
(zh)
|
2016-04-29 |
2019-02-05 |
阿拉伊姆药品公司 |
用于预防和治疗与组织损伤相关的疾病和障碍的组织保护肽
|