CH542858A - Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat - Google Patents

Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat

Info

Publication number
CH542858A
CH542858A CH1664272A CH1664272A CH542858A CH 542858 A CH542858 A CH 542858A CH 1664272 A CH1664272 A CH 1664272A CH 1664272 A CH1664272 A CH 1664272A CH 542858 A CH542858 A CH 542858A
Authority
CH
Switzerland
Prior art keywords
diphosphacholine
cytidine
crystalline
preparation
ester monohydrate
Prior art date
Application number
CH1664272A
Other languages
German (de)
English (en)
Inventor
Nakamachi Hideo
Kamiya Kazuhide
Nishikawa Masao
Fujii Shoichiro
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CH542858A publication Critical patent/CH542858A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CH1664272A 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat CH542858A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3207269 1969-04-24

Publications (1)

Publication Number Publication Date
CH542858A true CH542858A (de) 1973-11-30

Family

ID=12348661

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1664272A CH542858A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat
CH621370A CH542857A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH621370A CH542857A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat

Country Status (10)

Country Link
US (1) US3687932A (enrdf_load_stackoverflow)
BE (1) BE749332A (enrdf_load_stackoverflow)
CA (1) CA954510A (enrdf_load_stackoverflow)
CH (2) CH542858A (enrdf_load_stackoverflow)
DE (1) DE2019308C3 (enrdf_load_stackoverflow)
FR (1) FR2042370B1 (enrdf_load_stackoverflow)
GB (1) GB1261872A (enrdf_load_stackoverflow)
LU (1) LU60789A1 (enrdf_load_stackoverflow)
NL (1) NL149812B (enrdf_load_stackoverflow)
PH (1) PH9528A (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207106B (it) * 1980-04-18 1989-05-17 Made Italiana Srl Ora Searle I Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale
IT1188178B (it) * 1985-07-05 1988-01-07 Bioresearch Spa Sali della citidin-difospocolina particolarmente idonei per uso orale
US5109126A (en) * 1988-12-06 1992-04-28 Worcester Foundation For Experimental Biology 5'[2'(3')-O-(2,4,6-trinitrophenyl) pyprimidine nucleoside]diphosphate 1-glycosides
US5215973A (en) * 1991-03-07 1993-06-01 Magis Farmaceutici S.P.A. Optically active and racemic hydrated diacetylesters of α-glycero-phosphoryl-choline
AU1944799A (en) * 1997-12-24 1999-07-19 Interneuron Pharmaceuticals, Inc. Hyperhydrated citicoline, process and use
CN103509073B (zh) * 2013-08-29 2016-01-06 洪军 一种胞磷胆碱钠化合物
ES2985104T3 (es) * 2016-10-06 2024-11-04 Kyowa Hakko Bio Co Ltd Cristal de citidina difosfato colina y procedimiento de producción del mismo

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071231A (en) * 1963-08-30 1967-06-07 Ajinomoto Kk Nucleosides
NL129626C (enrdf_load_stackoverflow) * 1964-04-08
US3317512A (en) * 1965-06-01 1967-05-02 Upjohn Co 5', 5'-dinucleoside phosphates
US3300479A (en) * 1965-08-05 1967-01-24 Upjohn Co Deazapurine riboside cyclic 3', 5'-phosphates and process therefor
US3471471A (en) * 1965-09-21 1969-10-07 Univ Sydney Adenosine derivatives and therapeutic preparations containing same

Also Published As

Publication number Publication date
DE2019308C3 (de) 1981-04-09
BE749332A (fr) 1970-10-22
FR2042370A1 (enrdf_load_stackoverflow) 1971-02-12
NL7005785A (enrdf_load_stackoverflow) 1970-10-27
US3687932A (en) 1972-08-29
PH9528A (en) 1976-01-09
NL149812B (nl) 1976-06-15
CH542857A (de) 1973-10-15
FR2042370B1 (enrdf_load_stackoverflow) 1974-08-09
DE2019308B2 (enrdf_load_stackoverflow) 1980-08-21
CA954510A (en) 1974-09-10
LU60789A1 (enrdf_load_stackoverflow) 1970-06-29
DE2019308A1 (de) 1971-05-13
GB1261872A (en) 1972-01-26

Similar Documents

Publication Publication Date Title
AT313481B (de) Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden
CH542247A (de) Verfahren zur Herstellung von 3-Octadecyloxy-propanol-(1)-phosphorsäure-monocholinester
CH533604A (de) Verfahren zur Herstellung von substituierten Phenylsulfonamido-Salicylsäuren
CH541566A (de) Verfahren zur Herstellung von Nucleosiden
CH537383A (de) Verfahren zur Herstellung von 2-Arylalkan-carbonsäuren
CH536310A (de) Verfahren zur Herstellung von Dibenzazepin-Derivaten
CH540934A (de) Verfahren zur Herstellung von 2-Halogenäthylphosphonsäuren
AT306253B (de) Verfahren zur Herstellung von neuen Adenosin-5'-carbonsäurederivaten
AT313912B (de) Verfahren zur Herstellung von Azetidinonen-(2)
CH542858A (de) Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat
CH532584A (de) Verfahren zur Herstellung substituierter N-Cycloalkylarylamino-imidazoline-(2)
CH532547A (de) Verfahren zur Herstellung von Nonadecapentaencarbonsäuremethylester
AT305230B (de) Verfahren zur Herstellung von 2-Äthylhexanal-(1)
CH527845A (de) Verfahren zur Herstellung von Adenosinderivaten
CH513822A (de) Verfahren zur Herstellung von Indanyl-N-methylcarbaminsäureestern
CH540906A (de) Verfahren zur Herstellung von 7'-Formylzearalan
CH521313A (de) Verfahren zur Herstellung von Phenylalaminderivaten
AT308980B (de) Verfahren zur Herstellung von 21-Desoxy-21-N-(N'-methylpiperazinyl)-prednisolon
CH507304A (de) Verfahren zur Herstellung von Thionophosphonsäureestern
CH482729A (de) Verfahren zur Herstellung von O-Alkyl-O-aryl-thiolphosphorsäureestern
CH521304A (de) Verfahren zur Herstellung von Fluorameisensäureestern
CH492670A (de) Verfahren zur Herstellung von y-Chloracetessigsäureester
CH519011A (de) Verfahren zur Herstellung von Naphthalimidverbindungen
CH533644A (de) Verfahren zur Herstellung von Thiophosphorsäureesteramiden
AT314506B (de) Verfahren zur Herstellung von 4-Hydroxyphenylglycin

Legal Events

Date Code Title Description
PL Patent ceased