CH542857A - Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat - Google Patents

Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat

Info

Publication number
CH542857A
CH542857A CH621370A CH621370A CH542857A CH 542857 A CH542857 A CH 542857A CH 621370 A CH621370 A CH 621370A CH 621370 A CH621370 A CH 621370A CH 542857 A CH542857 A CH 542857A
Authority
CH
Switzerland
Prior art keywords
phatcholinester
diphos
cytidine
monohydrate
crystalline
Prior art date
Application number
CH621370A
Other languages
English (en)
Inventor
Nakamachi Hideo
Kamiya Kazuhide
Nishikawa Masao
Fujii Shoichiro
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CH542857A publication Critical patent/CH542857A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH621370A 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat CH542857A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3207269 1969-04-24

Publications (1)

Publication Number Publication Date
CH542857A true CH542857A (de) 1973-10-15

Family

ID=12348661

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1664272A CH542858A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat
CH621370A CH542857A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1664272A CH542858A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat

Country Status (10)

Country Link
US (1) US3687932A (de)
BE (1) BE749332A (de)
CA (1) CA954510A (de)
CH (2) CH542858A (de)
DE (1) DE2019308C3 (de)
FR (1) FR2042370B1 (de)
GB (1) GB1261872A (de)
LU (1) LU60789A1 (de)
NL (1) NL149812B (de)
PH (1) PH9528A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207106B (it) * 1980-04-18 1989-05-17 Made Italiana Srl Ora Searle I Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale
IT1188178B (it) * 1985-07-05 1988-01-07 Bioresearch Spa Sali della citidin-difospocolina particolarmente idonei per uso orale
US5109126A (en) * 1988-12-06 1992-04-28 Worcester Foundation For Experimental Biology 5'[2'(3')-O-(2,4,6-trinitrophenyl) pyprimidine nucleoside]diphosphate 1-glycosides
US5215973A (en) * 1991-03-07 1993-06-01 Magis Farmaceutici S.P.A. Optically active and racemic hydrated diacetylesters of α-glycero-phosphoryl-choline
AU1944799A (en) * 1997-12-24 1999-07-19 Interneuron Pharmaceuticals, Inc. Hyperhydrated citicoline, process and use
CN103509073B (zh) * 2013-08-29 2016-01-06 洪军 一种胞磷胆碱钠化合物
CN117069780A (zh) * 2016-10-06 2023-11-17 协和发酵生化株式会社 胞苷二磷酸胆碱的晶体及其制造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071231A (en) * 1963-08-30 1967-06-07 Ajinomoto Kk Nucleosides
NL129626C (de) * 1964-04-08
US3317512A (en) * 1965-06-01 1967-05-02 Upjohn Co 5', 5'-dinucleoside phosphates
US3300479A (en) * 1965-08-05 1967-01-24 Upjohn Co Deazapurine riboside cyclic 3', 5'-phosphates and process therefor
US3471471A (en) * 1965-09-21 1969-10-07 Univ Sydney Adenosine derivatives and therapeutic preparations containing same

Also Published As

Publication number Publication date
LU60789A1 (de) 1970-06-29
DE2019308B2 (de) 1980-08-21
NL149812B (nl) 1976-06-15
GB1261872A (en) 1972-01-26
US3687932A (en) 1972-08-29
DE2019308A1 (de) 1971-05-13
CH542858A (de) 1973-11-30
FR2042370B1 (de) 1974-08-09
DE2019308C3 (de) 1981-04-09
FR2042370A1 (de) 1971-02-12
PH9528A (en) 1976-01-09
CA954510A (en) 1974-09-10
BE749332A (fr) 1970-10-22
NL7005785A (de) 1970-10-27

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Legal Events

Date Code Title Description
PL Patent ceased