CH542857A - Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat - Google Patents

Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat

Info

Publication number
CH542857A
CH542857A CH621370A CH621370A CH542857A CH 542857 A CH542857 A CH 542857A CH 621370 A CH621370 A CH 621370A CH 621370 A CH621370 A CH 621370A CH 542857 A CH542857 A CH 542857A
Authority
CH
Switzerland
Prior art keywords
phatcholinester
diphos
cytidine
monohydrate
crystalline
Prior art date
Application number
CH621370A
Other languages
English (en)
Inventor
Nakamachi Hideo
Kamiya Kazuhide
Nishikawa Masao
Fujii Shoichiro
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CH542857A publication Critical patent/CH542857A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CH621370A 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat CH542857A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3207269 1969-04-24

Publications (1)

Publication Number Publication Date
CH542857A true CH542857A (de) 1973-10-15

Family

ID=12348661

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1664272A CH542858A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat
CH621370A CH542857A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1664272A CH542858A (de) 1969-04-24 1970-04-24 Verfahren zur Herstellung von kristallinem Cytidin-5'-diphosphatcholinester-monohydrat

Country Status (10)

Country Link
US (1) US3687932A (de)
BE (1) BE749332A (de)
CA (1) CA954510A (de)
CH (2) CH542858A (de)
DE (1) DE2019308C3 (de)
FR (1) FR2042370B1 (de)
GB (1) GB1261872A (de)
LU (1) LU60789A1 (de)
NL (1) NL149812B (de)
PH (1) PH9528A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207106B (it) * 1980-04-18 1989-05-17 Made Italiana Srl Ora Searle I Preparazione farmaceutica contenente citidin disfofocolina assorbibile per via orale
IT1188178B (it) * 1985-07-05 1988-01-07 Bioresearch Spa Sali della citidin-difospocolina particolarmente idonei per uso orale
US5109126A (en) * 1988-12-06 1992-04-28 Worcester Foundation For Experimental Biology 5'[2'(3')-O-(2,4,6-trinitrophenyl) pyprimidine nucleoside]diphosphate 1-glycosides
US5215973A (en) * 1991-03-07 1993-06-01 Magis Farmaceutici S.P.A. Optically active and racemic hydrated diacetylesters of α-glycero-phosphoryl-choline
AU1944799A (en) * 1997-12-24 1999-07-19 Interneuron Pharmaceuticals, Inc. Hyperhydrated citicoline, process and use
CN103509073B (zh) * 2013-08-29 2016-01-06 洪军 一种胞磷胆碱钠化合物
US11186605B2 (en) * 2016-10-06 2021-11-30 Kyowa Hakko Bio Co., Ltd. Crystal of cytidine diphosphate choline and production method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071231A (en) * 1963-08-30 1967-06-07 Ajinomoto Kk Nucleosides
NL129626C (de) * 1964-04-08
US3317512A (en) * 1965-06-01 1967-05-02 Upjohn Co 5', 5'-dinucleoside phosphates
US3300479A (en) * 1965-08-05 1967-01-24 Upjohn Co Deazapurine riboside cyclic 3', 5'-phosphates and process therefor
US3471471A (en) * 1965-09-21 1969-10-07 Univ Sydney Adenosine derivatives and therapeutic preparations containing same

Also Published As

Publication number Publication date
NL149812B (nl) 1976-06-15
DE2019308B2 (de) 1980-08-21
US3687932A (en) 1972-08-29
CH542858A (de) 1973-11-30
FR2042370A1 (de) 1971-02-12
GB1261872A (en) 1972-01-26
DE2019308A1 (de) 1971-05-13
BE749332A (fr) 1970-10-22
CA954510A (en) 1974-09-10
FR2042370B1 (de) 1974-08-09
LU60789A1 (de) 1970-06-29
PH9528A (en) 1976-01-09
DE2019308C3 (de) 1981-04-09
NL7005785A (de) 1970-10-27

Similar Documents

Publication Publication Date Title
AT313481B (de) Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden
CH541566A (de) Verfahren zur Herstellung von Nucleosiden
AT298508B (de) Verfahren zur Herstellung von Mercaptoalkylalkoxysilanen
CH536310A (de) Verfahren zur Herstellung von Dibenzazepin-Derivaten
AT311560B (de) Verfahren zur Herstellung von 2-Thio-pyrimidin-nucleosiden
AT313912B (de) Verfahren zur Herstellung von Azetidinonen-(2)
CH542857A (de) Verfahren zur Herstellung von kristallinem Cytidin-5'-diphos-phatcholinester-monohydrat
CH532584A (de) Verfahren zur Herstellung substituierter N-Cycloalkylarylamino-imidazoline-(2)
AT305230B (de) Verfahren zur Herstellung von 2-Äthylhexanal-(1)
CH540906A (de) Verfahren zur Herstellung von 7'-Formylzearalan
AT308980B (de) Verfahren zur Herstellung von 21-Desoxy-21-N-(N'-methylpiperazinyl)-prednisolon
CH521313A (de) Verfahren zur Herstellung von Phenylalaminderivaten
CH497428A (de) Verfahren zur Herstellung von 1-Formyl-3-nitro-azacyclo-heptanon-(2)
AT296961B (de) Verfahren zur Herstellung von Alkyldihydroxybenzolen
AT289052B (de) Verfahren zur Herstellung von 3-Ketobutanol-(1)
CH537968A (de) Verfahren zur Herstellung von 2,2'-Diacylamino-1,1'-dianthrachinonylen
CH538469A (de) Verfahren zur Herstellung von substituierten Tetralonen
CH523903A (de) Verfahren zur Herstellung von substituierten 3-Amino-benzothiophenen
CH544794A (de) Verfahren zur Herstellung von 1-Alkoxy-anthrachinonen
AT303277B (de) Verfahren zur herstellung von neuem 9 alpha-fluor-16-fluormethylenprednisolon-21-oenanthat
AT296297B (de) Verfahren zur Herstellung von N-Tritylimidazolen und -triazolen
AT299905B (de) Verfahren zur Herstellung von β-Acetoxypivalinaldehyd
AT299197B (de) Verfahren zur Herstellung von 3-Phenyl-5-tert.-butyl-oxadiazolonen-(2)
CH510677A (de) Verfahren zur Herstellung von N-Cinnamyl-N'-benzhydrylpiperazinen
CH516547A (de) Verfahren zur Herstellung von 14B-Hydroxy-3-oxo-5a-card-20(22)-enoliden

Legal Events

Date Code Title Description
PL Patent ceased