CA954510A - Crystalline cytidine-5'-diphosphate choline monohydrate and production thereof - Google Patents

Crystalline cytidine-5'-diphosphate choline monohydrate and production thereof

Info

Publication number
CA954510A
CA954510A CA081,038A CA81038A CA954510A CA 954510 A CA954510 A CA 954510A CA 81038 A CA81038 A CA 81038A CA 954510 A CA954510 A CA 954510A
Authority
CA
Canada
Prior art keywords
cytidine
crystalline
production
diphosphate choline
monohydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA081,038A
Inventor
Masao Nishikawa
Shoichiro Fujii
Kazuhide Kamiya
Hideo Nakamachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of CA954510A publication Critical patent/CA954510A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA081,038A 1969-04-24 1970-04-24 Crystalline cytidine-5'-diphosphate choline monohydrate and production thereof Expired CA954510A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3207269 1969-04-24

Publications (1)

Publication Number Publication Date
CA954510A true CA954510A (en) 1974-09-10

Family

ID=12348661

Family Applications (1)

Application Number Title Priority Date Filing Date
CA081,038A Expired CA954510A (en) 1969-04-24 1970-04-24 Crystalline cytidine-5'-diphosphate choline monohydrate and production thereof

Country Status (10)

Country Link
US (1) US3687932A (en)
BE (1) BE749332A (en)
CA (1) CA954510A (en)
CH (2) CH542857A (en)
DE (1) DE2019308C3 (en)
FR (1) FR2042370B1 (en)
GB (1) GB1261872A (en)
LU (1) LU60789A1 (en)
NL (1) NL149812B (en)
PH (1) PH9528A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207106B (en) * 1980-04-18 1989-05-17 Made Italiana Srl Ora Searle I PHARMACEUTICAL PREPARATION CONTAINING CITIDIN DISFOFOCOLINA ABSORBABLE ORALLY
IT1188178B (en) * 1985-07-05 1988-01-07 Bioresearch Spa CITIDIN-DIPHOSPOCOLINE SALTS PARTICULARLY SUITABLE FOR ORAL USE
US5109126A (en) * 1988-12-06 1992-04-28 Worcester Foundation For Experimental Biology 5'[2'(3')-O-(2,4,6-trinitrophenyl) pyprimidine nucleoside]diphosphate 1-glycosides
US5215973A (en) * 1991-03-07 1993-06-01 Magis Farmaceutici S.P.A. Optically active and racemic hydrated diacetylesters of α-glycero-phosphoryl-choline
CA2316989A1 (en) * 1997-12-24 1999-07-08 Interneuron Pharmaceuticals, Inc. Hyperhydrated citicoline, process and use
CN103509073B (en) * 2013-08-29 2016-01-06 洪军 A kind of Citicoline sodium compound
CN117069780A (en) * 2016-10-06 2023-11-17 协和发酵生化株式会社 Crystal of cytidine diphosphate choline and method for producing same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071231A (en) * 1963-08-30 1967-06-07 Ajinomoto Kk Nucleosides
NL129626C (en) * 1964-04-08
US3317512A (en) * 1965-06-01 1967-05-02 Upjohn Co 5', 5'-dinucleoside phosphates
US3300479A (en) * 1965-08-05 1967-01-24 Upjohn Co Deazapurine riboside cyclic 3', 5'-phosphates and process therefor
US3471471A (en) * 1965-09-21 1969-10-07 Univ Sydney Adenosine derivatives and therapeutic preparations containing same

Also Published As

Publication number Publication date
DE2019308C3 (en) 1981-04-09
LU60789A1 (en) 1970-06-29
BE749332A (en) 1970-10-22
NL149812B (en) 1976-06-15
DE2019308B2 (en) 1980-08-21
PH9528A (en) 1976-01-09
FR2042370B1 (en) 1974-08-09
DE2019308A1 (en) 1971-05-13
FR2042370A1 (en) 1971-02-12
US3687932A (en) 1972-08-29
GB1261872A (en) 1972-01-26
CH542858A (en) 1973-11-30
CH542857A (en) 1973-10-15
NL7005785A (en) 1970-10-27

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