CH542858A - Process for the preparation of crystalline cytidine-5'-diphosphacholine ester monohydrate - Google Patents

Process for the preparation of crystalline cytidine-5'-diphosphacholine ester monohydrate

Info

Publication number
CH542858A
CH542858A CH1664272A CH1664272A CH542858A CH 542858 A CH542858 A CH 542858A CH 1664272 A CH1664272 A CH 1664272A CH 1664272 A CH1664272 A CH 1664272A CH 542858 A CH542858 A CH 542858A
Authority
CH
Switzerland
Prior art keywords
diphosphacholine
cytidine
crystalline
preparation
ester monohydrate
Prior art date
Application number
CH1664272A
Other languages
German (de)
Inventor
Nakamachi Hideo
Kamiya Kazuhide
Nishikawa Masao
Fujii Shoichiro
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of CH542858A publication Critical patent/CH542858A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CH1664272A 1969-04-24 1970-04-24 Process for the preparation of crystalline cytidine-5'-diphosphacholine ester monohydrate CH542858A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3207269 1969-04-24

Publications (1)

Publication Number Publication Date
CH542858A true CH542858A (en) 1973-11-30

Family

ID=12348661

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1664272A CH542858A (en) 1969-04-24 1970-04-24 Process for the preparation of crystalline cytidine-5'-diphosphacholine ester monohydrate
CH621370A CH542857A (en) 1969-04-24 1970-04-24 Process for the preparation of crystalline cytidine-5'-diphos-phatcholinester-monohydrate

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH621370A CH542857A (en) 1969-04-24 1970-04-24 Process for the preparation of crystalline cytidine-5'-diphos-phatcholinester-monohydrate

Country Status (10)

Country Link
US (1) US3687932A (en)
BE (1) BE749332A (en)
CA (1) CA954510A (en)
CH (2) CH542858A (en)
DE (1) DE2019308C3 (en)
FR (1) FR2042370B1 (en)
GB (1) GB1261872A (en)
LU (1) LU60789A1 (en)
NL (1) NL149812B (en)
PH (1) PH9528A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207106B (en) * 1980-04-18 1989-05-17 Made Italiana Srl Ora Searle I PHARMACEUTICAL PREPARATION CONTAINING CITIDIN DISFOFOCOLINA ABSORBABLE ORALLY
IT1188178B (en) * 1985-07-05 1988-01-07 Bioresearch Spa CITIDIN-DIPHOSPOCOLINE SALTS PARTICULARLY SUITABLE FOR ORAL USE
US5109126A (en) * 1988-12-06 1992-04-28 Worcester Foundation For Experimental Biology 5'[2'(3')-O-(2,4,6-trinitrophenyl) pyprimidine nucleoside]diphosphate 1-glycosides
US5215973A (en) * 1991-03-07 1993-06-01 Magis Farmaceutici S.P.A. Optically active and racemic hydrated diacetylesters of α-glycero-phosphoryl-choline
JP4530534B2 (en) * 1997-12-24 2010-08-25 フエルレル インターナショナル、ソシエダッド アノニマ Hyperhydrated citicoline, process and use
CN103509073B (en) * 2013-08-29 2016-01-06 洪军 A kind of Citicoline sodium compound
AU2017341136B2 (en) * 2016-10-06 2021-07-08 Kyowa Hakko Bio Co., Ltd. Crystal of cytidine diphosphate choline and production method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071231A (en) * 1963-08-30 1967-06-07 Ajinomoto Kk Nucleosides
NL129626C (en) * 1964-04-08
US3317512A (en) * 1965-06-01 1967-05-02 Upjohn Co 5', 5'-dinucleoside phosphates
US3300479A (en) * 1965-08-05 1967-01-24 Upjohn Co Deazapurine riboside cyclic 3', 5'-phosphates and process therefor
US3471471A (en) * 1965-09-21 1969-10-07 Univ Sydney Adenosine derivatives and therapeutic preparations containing same

Also Published As

Publication number Publication date
CA954510A (en) 1974-09-10
GB1261872A (en) 1972-01-26
LU60789A1 (en) 1970-06-29
PH9528A (en) 1976-01-09
DE2019308C3 (en) 1981-04-09
NL7005785A (en) 1970-10-27
FR2042370A1 (en) 1971-02-12
FR2042370B1 (en) 1974-08-09
DE2019308A1 (en) 1971-05-13
DE2019308B2 (en) 1980-08-21
NL149812B (en) 1976-06-15
CH542857A (en) 1973-10-15
US3687932A (en) 1972-08-29
BE749332A (en) 1970-10-22

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Legal Events

Date Code Title Description
PL Patent ceased