CH295325A - Process for the preparation of a quaternary ammonium compound of a bis-aminoalkoxy-alkane. - Google Patents

Process for the preparation of a quaternary ammonium compound of a bis-aminoalkoxy-alkane.

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Publication number
CH295325A
CH295325A CH295325DA CH295325A CH 295325 A CH295325 A CH 295325A CH 295325D A CH295325D A CH 295325DA CH 295325 A CH295325 A CH 295325A
Authority
CH
Switzerland
Prior art keywords
bis
alkane
quaternary ammonium
preparation
ammonium compound
Prior art date
Application number
Other languages
German (de)
Inventor
Ag J R Geigy
Original Assignee
Ag J R Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ag J R Geigy filed Critical Ag J R Geigy
Publication of CH295325A publication Critical patent/CH295325A/en

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Description

  

      Verfahren    zur     Herstellung    einer     quaternären        Anunoniumverbindung          eines        Bis-aminoalkoxy-alkans.       Gegenstand vorliegenden Patentes ist ein  Verfahren zur Herstellung einer     quaternären          Ammonitunverbindung        eines        Bis-aminoalkoxv-          alkans.    Das Verfahren ist.

   dadurch gekenn  zeichnet, dass man auf ein     Mol        1,10-Bis-(ss-          brom-äthoxy)-dekan        zwei        Mol        Trimethylamin     einwirken lässt.  



  Die erhaltene neue     Verbindung,    das     1,10-          Bis-        (ss-t.rimethylammonium-äthoxy)-dekan-di-          bromidy    schmilzt. bei 192 bis 193 . Sie soll  therapeutische Verwendung finden.  



  <I>Beispiel:</I>  3,88 Teile     1,10-Bis-(ss=brom-äthoxy)-dekan     werden in 12 Teilen absolutem Methanol ge  löst, mit 7 Teilen einer     benzolischen        Trime-          thylaminlösung        (32        %)        versetzt        und.        im    Ein-         schmelzrohr    4     Stunden    im siedenden Wasser  bar erwärmt.

   Die Lösung     wird    mit etwas  trockenem Essigester versetzt und bis zur       beginnenden        Kristallisation        eingedampft.    Das       erhaltene    1,10 - Bis - (ss -     ti@imethylammoniiun-          äthoxy)-de'kan-di@bromid    schmilzt bei 192 bis  193 .



      Process for the preparation of a quaternary ammonium compound of a bis-aminoalkoxyalkane. The subject of the present patent is a process for the preparation of a quaternary ammonite compound of a bis-aminoalkoxy alkane. The procedure is.

   characterized in that one mole of 1,10-bis (ss- bromo-ethoxy) decane is allowed to act on two moles of trimethylamine.



  The new compound obtained, the 1,10-bis- (ss-t.rimethylammonium-ethoxy) -dekan-di-bromidy melts. at 192 to 193. It should find therapeutic use.



  <I> Example: </I> 3.88 parts of 1,10-bis (ss = bromo-ethoxy) -dekan are dissolved in 12 parts of absolute methanol, and 7 parts of a benzene trimethylamine solution (32%) are added and. heated in the melting tube in boiling water for 4 hours.

   The solution is mixed with a little dry ethyl acetate and evaporated until crystallization begins. The 1,10 - bis - (ss - ti @ imethylammoniiun- äthoxy) -de'kan-di @ bromide melts at 192 to 193.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung einer quater- nären Ammoniumverbindung eines Bis-amino- alkoxy-alkans, dadurch gekennzeichnet, dass man auf ein Mol 1,10 Bis-(ss4brom-äthoxy)- dekan zwei Mol 'Trimethylamin einwirken lässt. Die erhaltene neue Verbindung, das 1, Claim: Process for the production of a quaternary ammonium compound of a bis-amino-alkoxy-alkane, characterized in that two moles of trimethylamine are allowed to act on one mole of 1.10 bis- (ss4bromo-ethoxy) decane. The received new connection, the 1, 10- Bis- (ss-trimethylammonium-;äthoxy) -.dekan-di- bromid, schmilzt bei 192 bis 193 . 10-bis- (ss-trimethylammonium-; ethoxy) -dekan-di-bromide, melting at 192 to 193.
CH295325D 1949-12-07 1949-12-07 Process for the preparation of a quaternary ammonium compound of a bis-aminoalkoxy-alkane. CH295325A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH295325T 1949-12-07
CH291680T 1952-04-21

Publications (1)

Publication Number Publication Date
CH295325A true CH295325A (en) 1953-12-15

Family

ID=25733124

Family Applications (1)

Application Number Title Priority Date Filing Date
CH295325D CH295325A (en) 1949-12-07 1949-12-07 Process for the preparation of a quaternary ammonium compound of a bis-aminoalkoxy-alkane.

Country Status (1)

Country Link
CH (1) CH295325A (en)

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