CA987325A - Process for producing triiodoisophthalic acid monoamino acid amide x-ray contrast media - Google Patents

Process for producing triiodoisophthalic acid monoamino acid amide x-ray contrast media

Info

Publication number
CA987325A
CA987325A CA163,941A CA163941A CA987325A CA 987325 A CA987325 A CA 987325A CA 163941 A CA163941 A CA 163941A CA 987325 A CA987325 A CA 987325A
Authority
CA
Canada
Prior art keywords
producing
contrast media
ray contrast
acid
triiodoisophthalic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA163,941A
Other languages
English (en)
Other versions
CA163941S (en
Inventor
Eberhard Schroder
Wolfgang Beich
Erich Klieger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA987325A publication Critical patent/CA987325A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/36Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA163,941A 1972-02-16 1973-02-16 Process for producing triiodoisophthalic acid monoamino acid amide x-ray contrast media Expired CA987325A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2207950A DE2207950C3 (de) 1972-02-16 1972-02-16 Trijod-isophthalsäure-monoaminosäureamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Röntgenkontrastmittel

Publications (1)

Publication Number Publication Date
CA987325A true CA987325A (en) 1976-04-13

Family

ID=5836524

Family Applications (1)

Application Number Title Priority Date Filing Date
CA163,941A Expired CA987325A (en) 1972-02-16 1973-02-16 Process for producing triiodoisophthalic acid monoamino acid amide x-ray contrast media

Country Status (25)

Country Link
US (1) US3953501A (fi)
JP (2) JPS5741460B2 (fi)
AR (2) AR209257A1 (fi)
AT (1) AT319464B (fi)
AU (1) AU474420B2 (fi)
BE (1) BE795555A (fi)
CA (1) CA987325A (fi)
CH (2) CH576422A5 (fi)
CS (2) CS182796B2 (fi)
DD (1) DD103890A5 (fi)
DE (1) DE2207950C3 (fi)
DK (1) DK135484C (fi)
ES (1) ES411117A1 (fi)
FI (1) FI55294C (fi)
FR (1) FR2181737B1 (fi)
GB (1) GB1428985A (fi)
HU (1) HU165260B (fi)
IL (1) IL41556A (fi)
IT (1) IT1048111B (fi)
NL (1) NL7302174A (fi)
NO (1) NO138168C (fi)
SE (1) SE410597B (fi)
SU (2) SU563912A3 (fi)
YU (1) YU36154B (fi)
ZA (1) ZA731089B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021481A (en) * 1969-06-27 1977-05-03 Nyegaard & Co. A/S Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups
GB1488903A (en) * 1974-05-31 1977-10-19 Guerbet Sa X-ray contrast media
US4314055A (en) * 1975-09-29 1982-02-02 Mallinckrodt, Inc. 3,5-Disubstituted-2,4,6-triiodoanilides of polyhydroxy-monobasic acids
US4307072A (en) * 1976-03-12 1981-12-22 Mallinckrodt, Inc. N-Triiodobenzoylaminoacyl polyhydroxic amines
CH626873A5 (fi) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa
DE2852094A1 (de) * 1978-11-30 1980-06-12 Schering Ag Neue roentgenkontrastmittel
DE2928417A1 (de) * 1979-07-12 1981-01-29 Schering Ag Trijodierte basen
DK162045C (da) * 1982-10-01 1992-02-10 Nyegaard & Co As Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
US5866100A (en) * 1995-12-19 1999-02-02 Bracco Research S.A. Compositions for imaging of the gastrointestinal tract
US6265610B1 (en) 1999-01-12 2001-07-24 The University Of North Carolina At Chapel Hill Contrast media for angiography
CN117986193A (zh) * 2022-11-01 2024-05-07 科睿驰(深圳)医疗科技发展有限公司 显影化合物及其制备方法、显影栓塞材料及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA616717A (en) * 1961-03-21 Distelmaier Alfred Halogenated aminoisophthalic acids
DE1125587B (de) * 1957-03-06 1962-03-15 Schering Ag Roentgenkontrastmittel
US3009952A (en) * 1957-04-17 1961-11-21 Sterling Drug Inc Preparation of halogenated isophthalic acids
US3145197A (en) * 1961-06-26 1964-08-18 Mallinckrodt Chemical Works 5-acetamido-nu-alkyl-2, 4, 6-trhodoiso-phthalamic acid compounds
US3102880A (en) * 1960-09-06 1963-09-03 Mallinckrodt Chemical Works Isophthaloylbis-amino acid compounds
CH467626A (de) * 1965-03-31 1969-01-31 Chemie Linz Ag Röntgenkontrastmittel
FR6777M (fi) * 1967-07-10 1969-03-10
IL34803A (en) * 1969-06-27 1975-03-13 Nyegaard & Co As N-hydroxyalkyl substituted benzamides and iodo methanesulfonamide and radiological compositions containing them

Also Published As

Publication number Publication date
IT1048111B (it) 1980-11-20
FI55294C (fi) 1979-07-10
ZA731089B (en) 1973-11-28
BE795555A (fr) 1973-08-16
HU165260B (fi) 1974-07-27
FR2181737B1 (fi) 1975-11-21
DK135484B (da) 1977-05-09
JPS5741460B2 (fi) 1982-09-03
CS182796B2 (en) 1978-05-31
ES411117A1 (es) 1976-04-16
DE2207950B2 (de) 1980-01-31
CH590823A5 (fi) 1977-08-31
FR2181737A1 (fi) 1973-12-07
JPS57154152A (en) 1982-09-22
DD103890A5 (fi) 1974-02-12
IL41556A (en) 1976-11-30
IL41556A0 (en) 1973-07-30
SU555846A3 (ru) 1977-04-25
DE2207950C3 (de) 1980-09-25
AR207951A1 (es) 1976-11-22
NO138168B (no) 1978-04-10
NO138168C (no) 1978-07-26
AT319464B (de) 1974-12-27
US3953501A (en) 1976-04-27
DK135484C (da) 1977-10-17
CH576422A5 (fi) 1976-06-15
AU5181473A (en) 1974-08-08
JPS4892339A (fi) 1973-11-30
FI55294B (fi) 1979-03-30
SU563912A3 (ru) 1977-06-30
DE2207950A1 (de) 1973-08-23
YU36154B (en) 1982-02-25
GB1428985A (en) 1976-03-24
AU474420B2 (en) 1976-07-22
SE410597B (sv) 1979-10-22
CS182780B2 (en) 1978-05-31
NL7302174A (fi) 1973-08-20
JPS6059224B2 (ja) 1985-12-24
AR209257A1 (es) 1977-04-15
YU27673A (en) 1981-04-30

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