CA970377A - Benzonaphthyridine derivatives - Google Patents

Benzonaphthyridine derivatives

Info

Publication number
CA970377A
CA970377A CA112,767A CA112767A CA970377A CA 970377 A CA970377 A CA 970377A CA 112767 A CA112767 A CA 112767A CA 970377 A CA970377 A CA 970377A
Authority
CA
Canada
Prior art keywords
benzonaphthyridine derivatives
benzonaphthyridine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA112,767A
Other languages
English (en)
Inventor
Hans Ott
Rudolf Suess
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent Ltd
Original Assignee
Sandoz Patent Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708670A external-priority patent/CH527196A/de
Priority claimed from CH708970A external-priority patent/CH527822A/de
Application filed by Sandoz Patent Ltd filed Critical Sandoz Patent Ltd
Application granted granted Critical
Publication of CA970377A publication Critical patent/CA970377A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA112,767A 1970-05-13 1971-05-12 Benzonaphthyridine derivatives Expired CA970377A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708670A CH527196A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphthyridinderivate
CH708970A CH527822A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate

Publications (1)

Publication Number Publication Date
CA970377A true CA970377A (en) 1975-07-01

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
CA112,767A Expired CA970377A (en) 1970-05-13 1971-05-12 Benzonaphthyridine derivatives

Country Status (14)

Country Link
JP (1) JPS5432799B1 (enExample)
AT (1) AT326674B (enExample)
CA (1) CA970377A (enExample)
CS (2) CS162753B2 (enExample)
DE (1) DE2123328A1 (enExample)
DK (1) DK134488B (enExample)
ES (1) ES391026A1 (enExample)
FI (1) FI52089C (enExample)
FR (1) FR2100649B1 (enExample)
GB (1) GB1361441A (enExample)
NL (1) NL7106502A (enExample)
PL (1) PL76913B1 (enExample)
SE (1) SE387640B (enExample)
SU (1) SU423296A3 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
NL7314396A (enExample) * 1972-10-26 1974-05-01
BE880455A (fr) * 1979-01-22 1980-06-06 Sandoz Sa Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine
AU8106598A (en) 1997-06-03 1998-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine
PL200923B1 (pl) 1999-08-21 2009-02-27 Nycomed Gmbh Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
JP2007537233A (ja) * 2004-05-12 2007-12-20 ファイザー・プロダクツ・インク Nk1及びnk3アンタゴニストとしてのピペリジン誘導体
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
MX357121B (es) 2011-03-01 2018-06-27 Synergy Pharmaceuticals Inc Star Proceso de preparacion de agonistas c de guanilato ciclasa.
EP2958577A2 (en) 2013-02-25 2015-12-30 Synergy Pharmaceuticals Inc. Guanylate cyclase receptor agonists for use in colonic cleansing
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
CA2920856C (en) 2013-08-09 2026-03-03 Ardelyx, Inc. Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス, インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

Also Published As

Publication number Publication date
ATA412471A (de) 1975-03-15
JPS5432799B1 (enExample) 1979-10-16
DE2123328A1 (de) 1971-12-02
FI52089C (fi) 1977-06-10
PL76913B1 (en) 1975-02-28
DK134488B (da) 1976-11-15
GB1361441A (en) 1974-07-24
ES391026A1 (es) 1974-04-01
CS162753B2 (enExample) 1975-07-15
DK134488C (enExample) 1977-05-16
FR2100649B1 (enExample) 1974-08-30
AT326674B (de) 1975-12-29
NL7106502A (enExample) 1971-11-16
FR2100649A1 (enExample) 1972-03-24
CS167202B2 (enExample) 1976-04-29
FI52089B (enExample) 1977-02-28
SE387640B (sv) 1976-09-13
SU423296A3 (ru) 1974-04-05

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