CA963004A - Benzodiazepine compounds - Google Patents

Benzodiazepine compounds

Info

Publication number
CA963004A
CA963004A CA856,978A CA856978A CA963004A CA 963004 A CA963004 A CA 963004A CA 856978 A CA856978 A CA 856978A CA 963004 A CA963004 A CA 963004A
Authority
CA
Canada
Prior art keywords
benzodiazepine compounds
benzodiazepine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA856,978A
Other languages
English (en)
Inventor
Stanley C. Bell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of CA963004A publication Critical patent/CA963004A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/46Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/06Catalysts
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/18Copolymerisation of aldehydes or ketones
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2/00Addition polymers of aldehydes or cyclic oligomers thereof or of ketones; Addition copolymers thereof with less than 50 molar percent of other substances
    • C08G2/18Copolymerisation of aldehydes or ketones
    • C08G2/22Copolymerisation of aldehydes or ketones with epoxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polyethers (AREA)
CA856,978A 1961-08-29 1962-08-29 Benzodiazepine compounds Expired CA963004A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13456961A 1961-08-29 1961-08-29
US17717462A 1962-03-05 1962-03-05
US37974064A 1964-07-01 1964-07-01

Publications (1)

Publication Number Publication Date
CA963004A true CA963004A (en) 1975-02-18

Family

ID=27384605

Family Applications (1)

Application Number Title Priority Date Filing Date
CA856,978A Expired CA963004A (en) 1961-08-29 1962-08-29 Benzodiazepine compounds

Country Status (16)

Country Link
US (1) US3435005A (US07732459-20100608-C00012.png)
BE (2) BE666274A (US07732459-20100608-C00012.png)
BR (1) BR6242421D0 (US07732459-20100608-C00012.png)
CA (1) CA963004A (US07732459-20100608-C00012.png)
CH (4) CH417611A (US07732459-20100608-C00012.png)
CY (2) CY386A (US07732459-20100608-C00012.png)
DE (8) DE1795556C3 (US07732459-20100608-C00012.png)
DK (2) DK127600B (US07732459-20100608-C00012.png)
FI (4) FI46072C (US07732459-20100608-C00012.png)
FR (1) FR2217M (US07732459-20100608-C00012.png)
GB (5) GB1022645A (US07732459-20100608-C00012.png)
IL (1) IL23813A (US07732459-20100608-C00012.png)
LU (1) LU48964A1 (US07732459-20100608-C00012.png)
MY (3) MY6900102A (US07732459-20100608-C00012.png)
NL (1) NL6508496A (US07732459-20100608-C00012.png)
SE (5) SE322225B (US07732459-20100608-C00012.png)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL261058A (US07732459-20100608-C00012.png) * 1960-05-19
DE1300114B (de) * 1963-05-29 1969-07-31 American Home Prod Verfahren zur Herstellung von 5-Chlor-2-(2'-hydroxylamino-acetamido)-benzophenon
BE788899A (fr) * 1971-09-15 1973-01-02 Crc Ricerca Chim Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
FI783743A (fi) * 1977-12-14 1979-06-15 Gerot Pharmazeutika Foerfarande foer framstaellning av 3-di-n-propyl-acetoxi-benzodiazepin-2-oner
AT361492B (de) * 1978-12-18 1981-03-10 Gerot Pharmazeutika Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
US4540727A (en) * 1982-10-29 1985-09-10 Raychem Corporation Polyamide compositions
IT1165588B (it) * 1983-03-23 1987-04-22 Medosan Ind Biochimi 1,4 benzodiazepine terapeuticamente attive
IL151632A0 (en) * 2000-03-06 2003-04-10 Teva Pharma Process for preparing pure crystalline lorazepam
CN105601576A (zh) * 2016-03-18 2016-05-25 山东新华制药股份有限公司 氯甲西泮的晶型及其制备方法
UA119735C2 (uk) * 2018-12-20 2019-07-25 Анатолій Семенович Редер Фармацевтична сполука, спосіб її отримання та застосування як лікарського засобу

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2457224A (en) * 1945-07-03 1948-12-28 Du Pont Preparation of polydioxolane
BE522938A (US07732459-20100608-C00012.png) * 1951-08-22
US3027352A (en) * 1958-02-28 1962-03-27 Celanese Corp Copolymers
NL271273A (US07732459-20100608-C00012.png) * 1960-11-15
NL286742A (US07732459-20100608-C00012.png) * 1961-12-14
US3293219A (en) * 1963-07-10 1966-12-20 Tenneco Chem Polyacetal terpolymers containing randomly recurring groups derived from a methylene-bis-

Also Published As

Publication number Publication date
DE1795558A1 (de) 1971-11-18
GB1022644A (en) 1966-03-16
DE1795509B2 (de) 1973-09-06
DE1795553C3 (de) 1974-07-18
BE621819A (US07732459-20100608-C00012.png)
DE1645904B1 (de) 1970-08-06
DK114514B (da) 1969-07-07
GB1022642A (en) 1966-03-16
SE322225B (US07732459-20100608-C00012.png) 1970-04-06
LU48964A1 (US07732459-20100608-C00012.png) 1966-01-03
FI46849B (US07732459-20100608-C00012.png) 1973-04-02
CY498A (en) 1969-07-01
GB1078788A (en) 1967-08-09
DE1795553B2 (de) 1973-10-31
FI47371C (fi) 1973-11-12
CH446362A (de) 1967-11-15
CH417611A (de) 1966-07-31
SE335734B (US07732459-20100608-C00012.png) 1971-06-07
SE368575B (US07732459-20100608-C00012.png) 1974-07-08
DE1570365A1 (de) 1970-01-29
SE337033B (US07732459-20100608-C00012.png) 1971-07-26
GB1022643A (en) 1966-03-16
CH451519A (fr) 1968-05-15
DE1570365B2 (de) 1970-12-23
DE1795556C3 (de) 1974-04-25
FI46848B (US07732459-20100608-C00012.png) 1973-04-02
FI46072C (fi) 1972-12-11
GB1022645A (en) 1966-03-16
DE1795556A1 (de) 1972-01-27
DE1445412A1 (de) 1969-02-27
CH467790A (de) 1969-01-31
DE1795509A1 (de) 1972-04-13
DE1795553A1 (de) 1972-02-03
SE323080B (US07732459-20100608-C00012.png) 1970-04-27
US3435005A (en) 1969-03-25
IL23813A (en) 1969-04-30
DE1795509C3 (de) 1974-04-11
NL6508496A (US07732459-20100608-C00012.png) 1966-01-03
DE1645903C3 (de) 1978-05-03
MY7000021A (en) 1970-12-31
BR6242421D0 (pt) 1973-07-12
MY6900102A (en) 1969-12-31
FI47371B (US07732459-20100608-C00012.png) 1973-07-31
FI46848C (fi) 1973-07-10
MY6900345A (en) 1969-12-31
DE1645903A1 (de) 1970-01-02
BE666274A (US07732459-20100608-C00012.png) 1966-01-03
DE1795556B2 (de) 1973-09-13
FI46072B (US07732459-20100608-C00012.png) 1972-08-31
FR2217M (fr) 1963-12-16
DK127600B (da) 1973-12-03
FI46849C (fi) 1973-07-10
CY386A (en) 1967-04-25
DE1645903B2 (de) 1977-09-01

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