CA3222054A1 - 2, 8-diazaspiro[4.5]decane compounds - Google Patents
2, 8-diazaspiro[4.5]decane compounds Download PDFInfo
- Publication number
- CA3222054A1 CA3222054A1 CA3222054A CA3222054A CA3222054A1 CA 3222054 A1 CA3222054 A1 CA 3222054A1 CA 3222054 A CA3222054 A CA 3222054A CA 3222054 A CA3222054 A CA 3222054A CA 3222054 A1 CA3222054 A1 CA 3222054A1
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- compound
- optionally substituted
- independently selected
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Pens And Brushes (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021098358 | 2021-06-04 | ||
| CNPCT/CN2021/098358 | 2021-06-04 | ||
| PCT/CN2022/097025 WO2022253341A1 (en) | 2021-06-04 | 2022-06-03 | 2, 8-diazaspiro [4.5] decane compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3222054A1 true CA3222054A1 (en) | 2022-12-08 |
Family
ID=84322789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3222054A Pending CA3222054A1 (en) | 2021-06-04 | 2022-06-03 | 2, 8-diazaspiro[4.5]decane compounds |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240174696A1 (https=) |
| EP (1) | EP4347594A4 (https=) |
| JP (1) | JP2024521929A (https=) |
| KR (1) | KR20240016977A (https=) |
| CN (1) | CN117425654A (https=) |
| AR (1) | AR126078A1 (https=) |
| AU (1) | AU2022284188A1 (https=) |
| BR (1) | BR112023025393A2 (https=) |
| CA (1) | CA3222054A1 (https=) |
| TW (1) | TW202313608A (https=) |
| WO (1) | WO2022253341A1 (https=) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101679418A (zh) * | 2007-04-06 | 2010-03-24 | 诺瓦提斯公司 | 用作蛋白质激酶抑制剂的[2,6]萘啶类化合物 |
| JP2011529932A (ja) * | 2008-08-05 | 2011-12-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換ナフチリジン及び医薬としてのその使用 |
| WO2012167423A1 (en) * | 2011-06-08 | 2012-12-13 | Hutchison Medipharma Limited | Substituted pyridopyrazines as novel syk inhibitors |
| KR20140048216A (ko) * | 2011-06-29 | 2014-04-23 | 오츠카 세이야쿠 가부시키가이샤 | 치료 화합물로서의 퀴나졸린 및 관련된 사용 방법 |
| TWI675836B (zh) * | 2014-03-25 | 2019-11-01 | 美商伊格尼塔公司 | 非典型蛋白質激酶ｃ之氮雜喹唑啉抑制劑 |
| JOP20190257A1 (ar) * | 2017-04-28 | 2019-10-28 | Novartis Ag | مركبات أريل غير متجانسة ثنائية الحلقة مندمجة 6-6 واستخدامها كمثبطات lats |
| KR102328435B1 (ko) * | 2018-09-11 | 2021-11-18 | 재단법인 대구경북첨단의료산업진흥재단 | 신규 피리도-피리미딘 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 단백질 키나아제 관련 질환의 예방 또는 치료용 약학적 조성물 |
| WO2021050059A1 (en) * | 2019-09-11 | 2021-03-18 | Provincial Health Services Authority | Dna-pk inhibiting compounds |
-
2022
- 2022-06-03 JP JP2023574635A patent/JP2024521929A/ja active Pending
- 2022-06-03 AU AU2022284188A patent/AU2022284188A1/en active Pending
- 2022-06-03 CA CA3222054A patent/CA3222054A1/en active Pending
- 2022-06-03 BR BR112023025393A patent/BR112023025393A2/pt unknown
- 2022-06-03 AR ARP220101483A patent/AR126078A1/es not_active Application Discontinuation
- 2022-06-03 TW TW111120777A patent/TW202313608A/zh unknown
- 2022-06-03 WO PCT/CN2022/097025 patent/WO2022253341A1/en not_active Ceased
- 2022-06-03 EP EP22815380.5A patent/EP4347594A4/en active Pending
- 2022-06-03 KR KR1020237042291A patent/KR20240016977A/ko active Pending
- 2022-06-03 CN CN202280039813.4A patent/CN117425654A/zh active Pending
-
2023
- 2023-12-01 US US18/526,572 patent/US20240174696A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN117425654A (zh) | 2024-01-19 |
| TW202313608A (zh) | 2023-04-01 |
| AU2022284188A1 (en) | 2023-11-30 |
| WO2022253341A1 (en) | 2022-12-08 |
| AR126078A1 (es) | 2023-09-06 |
| EP4347594A1 (en) | 2024-04-10 |
| BR112023025393A2 (pt) | 2024-02-27 |
| KR20240016977A (ko) | 2024-02-06 |
| US20240174696A1 (en) | 2024-05-30 |
| JP2024521929A (ja) | 2024-06-04 |
| EP4347594A4 (en) | 2025-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 3RD ANNIV.) - STANDARD Year of fee payment: 3 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250523 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250523 |