CA3172665A1 - Treprostinil for use in the treatment of intersitial lung disease - Google Patents
Treprostinil for use in the treatment of intersitial lung disease Download PDFInfo
- Publication number
- CA3172665A1 CA3172665A1 CA3172665A CA3172665A CA3172665A1 CA 3172665 A1 CA3172665 A1 CA 3172665A1 CA 3172665 A CA3172665 A CA 3172665A CA 3172665 A CA3172665 A CA 3172665A CA 3172665 A1 CA3172665 A1 CA 3172665A1
- Authority
- CA
- Canada
- Prior art keywords
- weeks
- treprostinil
- administering
- lung disease
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dispersion Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063011810P | 2020-04-17 | 2020-04-17 | |
| US63/011,810 | 2020-04-17 | ||
| US202163160611P | 2021-03-12 | 2021-03-12 | |
| US63/160,611 | 2021-03-12 | ||
| PCT/US2021/027588 WO2021211916A1 (en) | 2020-04-17 | 2021-04-16 | Treprostinil for use in the treatment of intersitial lung disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3172665A1 true CA3172665A1 (en) | 2021-10-21 |
Family
ID=75870729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3172665A Pending CA3172665A1 (en) | 2020-04-17 | 2021-04-16 | Treprostinil for use in the treatment of intersitial lung disease |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US11826327B2 (https=) |
| EP (1) | EP4135707A1 (https=) |
| JP (1) | JP2023523557A (https=) |
| KR (1) | KR20230011929A (https=) |
| CN (1) | CN115916212A (https=) |
| AU (1) | AU2021255621A1 (https=) |
| CA (1) | CA3172665A1 (https=) |
| IL (1) | IL296567A (https=) |
| WO (1) | WO2021211916A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024510930A (ja) * | 2021-03-03 | 2024-03-12 | ユナイテッド セラピューティクス コーポレイション | トレプロスチニル及びそのプロドラッグの乾燥粉末組成物、及び、さらに(e)-3,6-ビス[4-(n-カルボニル-2-プロペニル)アミドブチル]-2,5-ジケトピペラジン(fdkp)を含む乾燥粉末組成物 |
| KR20240093906A (ko) * | 2021-10-27 | 2024-06-24 | 맨카인드 코포레이션 | 폐고혈압을 치료하기 위한 방법 및 조성물 |
| WO2023154705A1 (en) | 2022-02-08 | 2023-08-17 | United Therapeutics Corporation | Treprostinil iloprost combination therapy |
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| CA3102967A1 (en) * | 2018-06-07 | 2019-12-12 | Mannkind Corporation | Composition and method for inhalation |
| EP4017588A1 (en) | 2019-08-23 | 2022-06-29 | United Therapeutics Corporation | Treprostinil prodrugs |
-
2021
- 2021-04-16 JP JP2022562484A patent/JP2023523557A/ja active Pending
- 2021-04-16 WO PCT/US2021/027588 patent/WO2021211916A1/en not_active Ceased
- 2021-04-16 CA CA3172665A patent/CA3172665A1/en active Pending
- 2021-04-16 KR KR1020227038281A patent/KR20230011929A/ko active Pending
- 2021-04-16 US US17/233,061 patent/US11826327B2/en active Active
- 2021-04-16 EP EP21724428.4A patent/EP4135707A1/en active Pending
- 2021-04-16 CN CN202180042410.0A patent/CN115916212A/zh active Pending
- 2021-04-16 IL IL296567A patent/IL296567A/en unknown
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2024
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Also Published As
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| JP2023523557A (ja) | 2023-06-06 |
| AU2021255621A1 (en) | 2022-10-20 |
| US11826327B2 (en) | 2023-11-28 |
| US20210330621A1 (en) | 2021-10-28 |
| WO2021211916A1 (en) | 2021-10-21 |
| IL296567A (en) | 2022-11-01 |
| US20250049742A1 (en) | 2025-02-13 |
| US20260076929A1 (en) | 2026-03-19 |
| EP4135707A1 (en) | 2023-02-22 |
| KR20230011929A (ko) | 2023-01-25 |
| CN115916212A (zh) | 2023-04-04 |
| US20260076928A1 (en) | 2026-03-19 |
| US20260102366A1 (en) | 2026-04-16 |
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