CA3155812A1 - Methods of treating depressive disorders - Google Patents

Methods of treating depressive disorders Download PDF

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Publication number
CA3155812A1
CA3155812A1 CA3155812A CA3155812A CA3155812A1 CA 3155812 A1 CA3155812 A1 CA 3155812A1 CA 3155812 A CA3155812 A CA 3155812A CA 3155812 A CA3155812 A CA 3155812A CA 3155812 A1 CA3155812 A1 CA 3155812A1
Authority
CA
Canada
Prior art keywords
compound
human
administered
dose
disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3155812A
Other languages
English (en)
French (fr)
Inventor
Cynthia Louise HARDEN
Gregory N. Beatch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xenon Pharmaceuticals Inc
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Xenon Pharmaceuticals Inc
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Filing date
Publication date
Application filed by Xenon Pharmaceuticals Inc filed Critical Xenon Pharmaceuticals Inc
Publication of CA3155812A1 publication Critical patent/CA3155812A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3155812A 2019-11-08 2020-11-06 Methods of treating depressive disorders Pending CA3155812A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962932724P 2019-11-08 2019-11-08
US62/932,724 2019-11-08
PCT/US2020/059481 WO2021092439A1 (en) 2019-11-08 2020-11-06 Methods of treating depressive disorders

Publications (1)

Publication Number Publication Date
CA3155812A1 true CA3155812A1 (en) 2021-05-14

Family

ID=73643360

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3155812A Pending CA3155812A1 (en) 2019-11-08 2020-11-06 Methods of treating depressive disorders

Country Status (19)

Country Link
US (2) US12178811B2 (enExample)
EP (1) EP4054580A1 (enExample)
JP (2) JP2022553569A (enExample)
KR (1) KR20220098746A (enExample)
CN (1) CN114667146A (enExample)
AU (1) AU2020380961A1 (enExample)
BR (1) BR112022008580A2 (enExample)
CA (1) CA3155812A1 (enExample)
CL (1) CL2022001102A1 (enExample)
CO (1) CO2022008001A2 (enExample)
CR (1) CR20220250A (enExample)
GE (2) GEP20257732B (enExample)
IL (1) IL292678A (enExample)
MA (1) MA56607A1 (enExample)
MX (1) MX2022005490A (enExample)
PE (1) PE20221766A1 (enExample)
PH (1) PH12022551110A1 (enExample)
TW (1) TW202128162A (enExample)
WO (1) WO2021092439A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3155812A1 (en) 2019-11-08 2021-05-14 Cynthia Louise HARDEN Methods of treating depressive disorders
CA3159876A1 (en) 2019-12-06 2021-06-10 James MURROUGH Method of treatment with kcnq channel openers
GEAP202416349A (en) * 2021-02-09 2024-02-12 Xenon Pharmaceuticals Inc Conjoint therapy for treating seizure disorders
TW202245744A (zh) 2021-02-09 2022-12-01 加拿大商再諾製藥公司 治療失樂症之方法及用途
EP4392125A1 (en) * 2021-10-08 2024-07-03 Albert-Ludwigs-Universität Freiburg Treatment of psychiatric disorders with deep brain stimulation

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CA3155812A1 (en) 2019-11-08 2021-05-14 Cynthia Louise HARDEN Methods of treating depressive disorders
CA3159876A1 (en) 2019-12-06 2021-06-10 James MURROUGH Method of treatment with kcnq channel openers
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CN113698345B (zh) 2021-10-27 2022-02-01 上海挚盟医药科技有限公司 作为钾通道调节剂的化合物及其制备和应用

Also Published As

Publication number Publication date
TW202128162A (zh) 2021-08-01
MA56607A1 (fr) 2022-10-31
NZ787838A (en) 2025-08-29
GEAP202415942A (en) 2024-10-28
KR20220098746A (ko) 2022-07-12
IL292678A (en) 2022-07-01
JP2022553569A (ja) 2022-12-23
PH12022551110A1 (en) 2024-02-26
MX2022005490A (es) 2022-08-10
CR20220250A (es) 2022-08-19
CL2022001102A1 (es) 2023-01-27
CN114667146A (zh) 2022-06-24
GEP20257732B (en) 2025-02-10
CO2022008001A2 (es) 2022-06-10
AU2020380961A1 (en) 2022-05-26
EP4054580A1 (en) 2022-09-14
US20210161886A1 (en) 2021-06-03
US20250108044A1 (en) 2025-04-03
US12178811B2 (en) 2024-12-31
JP2026001049A (ja) 2026-01-06
BR112022008580A2 (pt) 2022-08-09
PE20221766A1 (es) 2022-11-11
WO2021092439A1 (en) 2021-05-14

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