CA3152591C - Lung cancer biomarkers and uses thereof - Google Patents

Lung cancer biomarkers and uses thereof Download PDF

Info

Publication number
CA3152591C
CA3152591C CA3152591A CA3152591A CA3152591C CA 3152591 C CA3152591 C CA 3152591C CA 3152591 A CA3152591 A CA 3152591A CA 3152591 A CA3152591 A CA 3152591A CA 3152591 C CA3152591 C CA 3152591C
Authority
CA
Canada
Prior art keywords
biomarkers
biomarker
lung cancer
individual
aptamer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3152591A
Other languages
English (en)
French (fr)
Other versions
CA3152591A1 (en
Inventor
Larry Gold
Marty Stanton
Edward N. Brody
Rachel M. Ostroff
Dominic Zichi
Alex A. E. Stewart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Somalogic Operating Co Inc
Original Assignee
Somalogic Operating Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Operating Co Inc filed Critical Somalogic Operating Co Inc
Publication of CA3152591A1 publication Critical patent/CA3152591A1/en
Application granted granted Critical
Publication of CA3152591C publication Critical patent/CA3152591C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Mathematical Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Databases & Information Systems (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Analysis (AREA)
  • Pure & Applied Mathematics (AREA)
  • Computational Mathematics (AREA)
  • Software Systems (AREA)
  • Algebra (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA3152591A 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof Active CA3152591C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9559308P 2008-09-09 2008-09-09
US61/095,593 2008-09-09
US15283709P 2009-02-16 2009-02-16
US61/152,837 2009-02-16
CA3011730A CA3011730C (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA3011730A Division CA3011730C (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof

Publications (2)

Publication Number Publication Date
CA3152591A1 CA3152591A1 (en) 2010-03-18
CA3152591C true CA3152591C (en) 2023-08-29

Family

ID=42005456

Family Applications (3)

Application Number Title Priority Date Filing Date
CA3152591A Active CA3152591C (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof
CA2734535A Active CA2734535C (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof
CA3011730A Active CA3011730C (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA2734535A Active CA2734535C (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof
CA3011730A Active CA3011730C (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof

Country Status (14)

Country Link
EP (1) EP2340506B1 (enExample)
JP (1) JP5701212B2 (enExample)
KR (1) KR101658347B1 (enExample)
CN (2) CN104198709A (enExample)
AU (2) AU2009291811B2 (enExample)
CA (3) CA3152591C (enExample)
DK (1) DK2340506T3 (enExample)
ES (1) ES2559758T3 (enExample)
GB (1) GB2478441B (enExample)
HK (1) HK1204062A1 (enExample)
HR (1) HRP20160127T1 (enExample)
MX (1) MX2011002322A (enExample)
SI (1) SI2340506T1 (enExample)
WO (1) WO2010030697A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10359425B2 (en) 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
PL3257953T3 (pl) 2009-03-12 2019-05-31 Cancer Prevention & Cure Ltd Sposoby identyfikacji, oceny, zapobiegania i terapii chorób płuc, ich zestawy, w tym do identyfikacji, oceny, zapobiegania i terapii chorób powiązanych z płcią
JP5905003B2 (ja) * 2010-07-09 2016-04-20 ソマロジック・インコーポレーテッド 肺癌バイオマーカーとその使用
MX350533B (es) 2010-08-13 2017-09-08 Somalogic Inc Biomarcadores de cancer pancreatico y usos de los mismos.
AU2012239943B2 (en) * 2011-04-07 2016-09-22 The Scripps Research Institute High-throughput screening for compounds modulating expression of cellular macromolecules
EP3825693A1 (en) * 2011-04-29 2021-05-26 Cancer Prevention And Cure, Ltd. Methods of identification and diagnosis of lung diseases using classification systems and kits thereof
BR112014006432B8 (pt) * 2011-10-24 2022-10-25 Somalogic Inc Método in vitro para diagnosticar se um indivíduo tem ou não câncer, método implementado por computador, produto de programa de computador
WO2013096845A2 (en) 2011-12-21 2013-06-27 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US9304137B2 (en) 2011-12-21 2016-04-05 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US11913957B2 (en) 2011-12-21 2024-02-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
RU2629799C2 (ru) * 2012-02-17 2017-09-04 Конинклейке Филипс Н.В. Оценка и наблюдение острого повреждения легких (ali)/синдрома острой дыхательной недостаточности (ards)
WO2014074682A1 (en) 2012-11-07 2014-05-15 Somalogic, Inc. Chronic obstructive pulmonary disease (copd) biomarkers and uses thereof
RU2677742C2 (ru) 2013-11-07 2019-01-21 Медиал Рисеч Лтд. Способы и системы оценки риска развития злокачественной опухоли легкого
CN108026584B (zh) * 2015-09-11 2021-12-10 适体科学株式会社 非小细胞肺癌诊断用蛋白质生物标志物组及利用其的非小细胞肺癌诊断方法
FR3050269B1 (fr) 2016-04-15 2018-05-11 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris (Espci) Procede de selection et de recuperation de produits et systeme associe
CN105823665A (zh) * 2016-05-13 2016-08-03 北京九州柏林生物科技有限公司 生物组织样本制备套液
RU2018145532A (ru) 2016-06-21 2020-07-23 Зе Уистар Инститьют Оф Анатоми Энд Байолоджи Композиции и способы диагностирования раковых заболеваний легких с помощью профилей экспрессии генов
JP6280997B1 (ja) * 2016-10-31 2018-02-14 株式会社Preferred Networks 疾患の罹患判定装置、疾患の罹患判定方法、疾患の特徴抽出装置及び疾患の特徴抽出方法
CN110709936A (zh) 2017-04-04 2020-01-17 肺癌蛋白质组学有限责任公司 用于早期肺癌预后的基于血浆的蛋白质概况分析
AU2018324195B2 (en) 2017-09-01 2024-12-12 Venn Biosciences Corporation Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring
AU2018373154B2 (en) * 2017-11-22 2025-08-07 Seattle Project Corp. Reducing junction epitope presentation for neoantigens
WO2019126343A1 (en) 2017-12-19 2019-06-27 The Wistar Institute Of Anatomy And Biology Compositions and methods for diagnosing lung cancers using gene expression profiles
US20210247387A1 (en) * 2018-06-22 2021-08-12 Somalogic, Inc. Improved proteomic multiplex assays
CN114026424B (zh) * 2019-06-21 2026-04-10 新加坡国立大学 用于确定肺癌的可能性的方法
CN110579611B (zh) * 2019-09-18 2023-01-31 郑州大学 一种用于肺癌早期筛查和诊断的联合检测血清标志物、试剂盒及检测方法
CN111047609B (zh) * 2020-03-13 2020-07-24 北京深睿博联科技有限责任公司 肺炎病灶分割方法和装置
CN113960235B (zh) * 2020-10-10 2023-03-14 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 生物标志物在制备肺癌检测试剂中的用途和方法
CN112557514B (zh) * 2020-12-22 2021-09-21 中国海洋大学 手持式海底沉积物样品剖面声学全自动测量装置
TW202242146A (zh) * 2021-01-13 2022-11-01 比利時商比利時意志有限公司 肺癌的檢測方法
IL330052A (en) * 2023-12-18 2026-08-01 Caris Mpi Inc Dynamic tissue classification

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596503B1 (en) * 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
US20030190602A1 (en) * 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
KR20030094281A (ko) * 2001-03-12 2003-12-11 모노젠, 인크. 세포에 기초한 질병상태의 검출 및 질병상태의 구별
CA2444691A1 (en) * 2001-04-18 2002-10-31 Protein Design Labs, Inc. Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
EP1739185A1 (en) * 2002-12-18 2007-01-03 Ciphergen Biosystems, Inc. Serum biomarkers in lung cancer
CN1225477C (zh) * 2003-03-28 2005-11-02 上海市疾病预防控制中心 肺癌早期血清特异蛋白及其应用
CN1455257A (zh) * 2003-05-23 2003-11-12 北京师范大学 一种利用表面修饰蛋白芯片进行肺癌诊断方法
EP2343384A3 (en) * 2004-03-23 2012-01-04 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancer
JP2005304497A (ja) * 2004-03-25 2005-11-04 Joji Inasawa 特定の癌関連遺伝子を用いる癌の検出方法及び癌の抑制方法
WO2005113798A2 (en) * 2004-04-15 2005-12-01 University Of Florida Research Foundation, Inc. Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining
US20060204951A1 (en) * 2004-04-26 2006-09-14 Judah Folkman Platelet biomarkers for the detection of disease
EP1778856A4 (en) * 2004-08-02 2008-05-28 Childrens Medical Center BLOOD BIOMARKER FOR CANCER
CN1873417A (zh) * 2005-06-02 2006-12-06 中国医学科学院肿瘤医院肿瘤研究所 一种用于诊断肺癌的蛋白质芯片
EP3147665A1 (en) * 2005-12-22 2017-03-29 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US7908091B2 (en) * 2006-03-17 2011-03-15 Prometheus Laboratories Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy
WO2008048120A2 (en) * 2006-10-17 2008-04-24 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
US20110119776A1 (en) * 2007-02-05 2011-05-19 Wong Kwok-Kin Methods of diagnosing and prognosing lung cancer
KR100846354B1 (ko) * 2007-03-21 2008-07-15 (주) 프로탄바이오 혈청 당단백질부터 분리한 폐암 진단용 마커
AU2008254786A1 (en) * 2007-05-18 2008-11-27 University Of Southern California Germline polymorphisms in the angiogenic pathway predict tumor recurrence in cancer therapy
US7888051B2 (en) * 2007-09-11 2011-02-15 Cancer Prevention And Cure, Ltd. Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues
WO2010003772A1 (en) * 2008-06-16 2010-01-14 Siemens Medical Solutions Diagnostics Gmbh Method for predicting adverse response to erythropoietin in breast cancer treatment
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
JP6114035B2 (ja) * 2010-02-10 2017-04-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 肺癌検出用唾液バイオマーカー

Also Published As

Publication number Publication date
EP2340506B1 (en) 2015-11-11
ES2559758T3 (es) 2016-02-15
JP5701212B2 (ja) 2015-04-15
KR101658347B1 (ko) 2016-09-21
CN102209968B (zh) 2016-05-04
CA3152591A1 (en) 2010-03-18
CN104198709A (zh) 2014-12-10
CA3011730A1 (en) 2010-03-18
EP2340506A4 (en) 2012-02-15
GB2478441A (en) 2011-09-07
CA3011730C (en) 2022-05-17
CA2734535A1 (en) 2010-03-18
HRP20160127T1 (hr) 2016-03-11
HK1204062A1 (en) 2015-11-06
HK1153834A1 (en) 2012-04-05
SI2340506T1 (sl) 2016-02-29
GB2478441B (en) 2013-03-27
AU2015249113A1 (en) 2015-11-12
EP2340506A1 (en) 2011-07-06
MX2011002322A (es) 2011-05-10
CA2734535C (en) 2018-08-28
AU2015249113B2 (en) 2017-09-07
AU2009291811B2 (en) 2015-10-29
JP2012502281A (ja) 2012-01-26
DK2340506T3 (en) 2016-02-08
CN102209968A (zh) 2011-10-05
KR20110063753A (ko) 2011-06-14
AU2009291811A1 (en) 2010-03-18
GB201106053D0 (en) 2011-05-25
WO2010030697A1 (en) 2010-03-18

Similar Documents

Publication Publication Date Title
CA2734535C (en) Lung cancer biomarkers and uses thereof
CA2801110C (en) Lung cancer biomarkers and uses thereof
US10359425B2 (en) Lung cancer biomarkers and uses thereof
CA2847188C (en) Non-small cell lung cancer biomarkers and uses thereof
US20100221752A2 (en) Ovarian Cancer Biomarkers and Uses Thereof
US20120143805A1 (en) Cancer Biomarkers and Uses Thereof
US20120165217A1 (en) Cancer Biomarkers and Uses Thereof
EP2748356A2 (en) Renal cell carcinoma biomarkers and uses thereof
EP2350917A1 (en) Ovarian cancer biomarkers and uses thereof
US20220065872A1 (en) Lung Cancer Biomarkers and Uses Thereof
HK1153834B (en) Lung cancer biomarkers and uses thereof
HK1196429B (en) Lung cancer biomarkers and uses thereof
HK1196429A (en) Lung cancer biomarkers and uses thereof

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220317

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 15TH ANNIV.) - STANDARD

Year of fee payment: 15

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20240830

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20240830

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20240830

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 16TH ANNIV.) - STANDARD

Year of fee payment: 16

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250905

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250909