CN104198709A - 肺癌生物标记及其用途 - Google Patents

肺癌生物标记及其用途 Download PDF

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Publication number
CN104198709A
CN104198709A CN201410477840.7A CN201410477840A CN104198709A CN 104198709 A CN104198709 A CN 104198709A CN 201410477840 A CN201410477840 A CN 201410477840A CN 104198709 A CN104198709 A CN 104198709A
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China
Prior art keywords
biomarker
biomarkers
individual
lung cancer
sample
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Pending
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CN201410477840.7A
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English (en)
Chinese (zh)
Inventor
L·戈尔德
M·斯坦顿
E·N·布罗迪
R·M·奥斯特罗夫
D·济奇
A·A·E·斯图尔特
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Somalogic Inc
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Somalogic Inc
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Publication of CN104198709A publication Critical patent/CN104198709A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • Organic Chemistry (AREA)
  • Mathematical Physics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Pure & Applied Mathematics (AREA)
  • Algebra (AREA)
  • Biophysics (AREA)
  • Mathematical Analysis (AREA)
  • Software Systems (AREA)
  • Databases & Information Systems (AREA)
  • Computational Mathematics (AREA)
  • Mathematical Optimization (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201410477840.7A 2008-09-09 2009-09-09 肺癌生物标记及其用途 Pending CN104198709A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9559308P 2008-09-09 2008-09-09
US61/095,593 2008-09-09
US15283709P 2009-02-16 2009-02-16
US61/152,837 2009-02-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200980144620.XA Division CN102209968B (zh) 2008-09-09 2009-09-09 肺癌生物标记蛋白的捕获剂在制备试剂盒中的用途

Publications (1)

Publication Number Publication Date
CN104198709A true CN104198709A (zh) 2014-12-10

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN201410477840.7A Pending CN104198709A (zh) 2008-09-09 2009-09-09 肺癌生物标记及其用途
CN200980144620.XA Active CN102209968B (zh) 2008-09-09 2009-09-09 肺癌生物标记蛋白的捕获剂在制备试剂盒中的用途

Family Applications After (1)

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CN200980144620.XA Active CN102209968B (zh) 2008-09-09 2009-09-09 肺癌生物标记蛋白的捕获剂在制备试剂盒中的用途

Country Status (14)

Country Link
EP (1) EP2340506B1 (enExample)
JP (1) JP5701212B2 (enExample)
KR (1) KR101658347B1 (enExample)
CN (2) CN104198709A (enExample)
AU (2) AU2009291811B2 (enExample)
CA (3) CA3011730C (enExample)
DK (1) DK2340506T3 (enExample)
ES (1) ES2559758T3 (enExample)
GB (1) GB2478441B (enExample)
HK (1) HK1204062A1 (enExample)
HR (1) HRP20160127T1 (enExample)
MX (1) MX2011002322A (enExample)
SI (1) SI2340506T1 (enExample)
WO (1) WO2010030697A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109073527A (zh) * 2016-04-15 2018-12-21 巴黎高等物理化学工业区 从乳液中回收产物的方法和系统
CN111630602A (zh) * 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
CN112638845A (zh) * 2018-06-22 2021-04-09 私募蛋白质体公司 改进的蛋白质组学多重测定

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US10359425B2 (en) 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
ES2703714T3 (es) 2009-03-12 2019-03-12 Cancer Prevention & Cure Ltd Métodos de identificación, evaluación, prevención y terapia de enfermedades pulmonares y kits de los mismos, incluida la identificación, evaluación, prevención y terapia de enfermedades en base al género
CA2801110C (en) * 2010-07-09 2021-10-05 Somalogic, Inc. Lung cancer biomarkers and uses thereof
CN106198980B (zh) 2010-08-13 2018-09-07 私募蛋白质体公司 胰腺癌生物标记及其用途
RU2612017C2 (ru) * 2011-04-07 2017-03-01 Де Скриппс Рисерч Инститьют Высокопроизводительный скрининг соединений, модулирующих экспрессию клеточных макромолекул
EP2702411A4 (en) * 2011-04-29 2015-07-22 Cancer Prevention & Cure Ltd METHOD FOR IDENTIFICATION AND DIAGNOSIS OF LUNG DISEASES USING CLASSIFICATION SYSTEMS AND KITS THEREFOR
JP5986638B2 (ja) * 2011-10-24 2016-09-06 ソマロジック・インコーポレーテッド 肺癌バイオマーカーおよびその使用
CA2860298A1 (en) 2011-12-21 2013-06-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
US9304137B2 (en) 2011-12-21 2016-04-05 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US11913957B2 (en) 2011-12-21 2024-02-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
EP2815343A2 (en) * 2012-02-17 2014-12-24 Koninklijke Philips N.V. Acute lung injury (ali)/acute respiratory distress syndrome (ards) assessment and monitoring
CN104812913B (zh) 2012-11-07 2019-03-15 私募蛋白质体公司 慢性阻塞性肺疾病(copd)生物标记及其用途
BR112016010322A2 (pt) * 2013-11-07 2017-08-08 Medial Res Ltd Método computadorizado de avaliação de risco de câncer de pulmão, meio legível por computador, sistema de avaliação de câncer de pulmão, e método de geração de um classificador para avaliação de risco de câncer de pulmão
JP6857185B2 (ja) * 2015-09-11 2021-04-14 アプタマー サイエンス インコーポレイテッドＡｐｔａｍｅｒ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． 非小細胞肺癌診断用タンパク質バイオマーカーパネル及びこれを用いた非小細胞肺癌診断方法
CN105823665A (zh) * 2016-05-13 2016-08-03 北京九州柏林生物科技有限公司 生物组织样本制备套液
CA3026809A1 (en) 2016-06-21 2017-12-28 The Wistar Institute Of Anatomy And Biology Compositions and methods for diagnosing lung cancers using gene expression profiles
JP6280997B1 (ja) * 2016-10-31 2018-02-14 株式会社Preferred Networks 疾患の罹患判定装置、疾患の罹患判定方法、疾患の特徴抽出装置及び疾患の特徴抽出方法
CN110709936A (zh) 2017-04-04 2020-01-17 肺癌蛋白质组学有限责任公司 用于早期肺癌预后的基于血浆的蛋白质概况分析
EP3676393A4 (en) 2017-09-01 2021-10-13 Venn Biosciences Corporation IDENTIFICATION AND USE OF GLYCOPEPTIDES AS BIOMARKERS FOR DIAGNOSIS AND TREATMENT MONITORING
EP3728630A4 (en) 2017-12-19 2021-11-17 The Wistar Institute Of Anatomy And Biology COMPOSITIONS AND METHODS OF DIAGNOSING LUNG CANCER USING GENE EXPRESSION PROFILES
WO2020256640A1 (en) * 2019-06-21 2020-12-24 National University Of Singapore Methods for determining the likelihood of lung cancer
CN110579611B (zh) * 2019-09-18 2023-01-31 郑州大学 一种用于肺癌早期筛查和诊断的联合检测血清标志物、试剂盒及检测方法
CN111047609B (zh) * 2020-03-13 2020-07-24 北京深睿博联科技有限责任公司 肺炎病灶分割方法和装置
CN113960235B (zh) * 2020-10-10 2023-03-14 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 生物标志物在制备肺癌检测试剂中的用途和方法
CN112557514B (zh) * 2020-12-22 2021-09-21 中国海洋大学 手持式海底沉积物样品剖面声学全自动测量装置
WO2025137139A1 (en) * 2023-12-18 2025-06-26 Caris Mpi, Inc. Dynamic tissue typing

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CN1455257A (zh) * 2003-05-23 2003-11-12 北京师范大学 一种利用表面修饰蛋白芯片进行肺癌诊断方法
CN1534045A (zh) * 2003-03-28 2004-10-06 上海市疾病预防控制中心 肺癌早期血清特异蛋白及其应用
US20050260697A1 (en) * 2004-04-15 2005-11-24 University Of Florida Research Foundation, Inc. Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining
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CN1873417A (zh) * 2005-06-02 2006-12-06 中国医学科学院肿瘤医院肿瘤研究所 一种用于诊断肺癌的蛋白质芯片
CN1977052A (zh) * 2004-03-23 2007-06-06 肿瘤疗法科学股份有限公司 用于诊断非小细胞肺癌的方法
US20070178504A1 (en) * 2005-12-22 2007-08-02 Tracey Colpitts Methods and marker combinations for screening for predisposition to lung cancer

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CA2419270A1 (en) * 2000-08-18 2002-02-28 East Carolina University Monoclonal antibody ds6, tumor-associated antigen ca6, and methods of use thereof
WO2002086443A2 (en) * 2001-04-18 2002-10-31 Protein Design Labs, Inc Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US20060223127A1 (en) * 2002-12-18 2006-10-05 Ciphergen Biosystems, Inc. Serum biomarkers in lung cancer
CN1534045A (zh) * 2003-03-28 2004-10-06 上海市疾病预防控制中心 肺癌早期血清特异蛋白及其应用
CN1455257A (zh) * 2003-05-23 2003-11-12 北京师范大学 一种利用表面修饰蛋白芯片进行肺癌诊断方法
CN1977052A (zh) * 2004-03-23 2007-06-06 肿瘤疗法科学股份有限公司 用于诊断非小细胞肺癌的方法
US20050260697A1 (en) * 2004-04-15 2005-11-24 University Of Florida Research Foundation, Inc. Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining
CN1873417A (zh) * 2005-06-02 2006-12-06 中国医学科学院肿瘤医院肿瘤研究所 一种用于诊断肺癌的蛋白质芯片
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109073527A (zh) * 2016-04-15 2018-12-21 巴黎高等物理化学工业区 从乳液中回收产物的方法和系统
US11396017B2 (en) 2016-04-15 2022-07-26 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris Method and system for recovering products from an emulsion
CN111630602A (zh) * 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
US11885815B2 (en) 2017-11-22 2024-01-30 Gritstone Bio, Inc. Reducing junction epitope presentation for neoantigens
CN112638845A (zh) * 2018-06-22 2021-04-09 私募蛋白质体公司 改进的蛋白质组学多重测定

Also Published As

Publication number Publication date
EP2340506A4 (en) 2012-02-15
WO2010030697A1 (en) 2010-03-18
HK1153834A1 (en) 2012-04-05
GB201106053D0 (en) 2011-05-25
CA3152591A1 (en) 2010-03-18
KR101658347B1 (ko) 2016-09-21
MX2011002322A (es) 2011-05-10
KR20110063753A (ko) 2011-06-14
CN102209968B (zh) 2016-05-04
HRP20160127T1 (hr) 2016-03-11
AU2015249113A1 (en) 2015-11-12
CA3011730A1 (en) 2010-03-18
AU2009291811B2 (en) 2015-10-29
AU2009291811A1 (en) 2010-03-18
HK1204062A1 (en) 2015-11-06
EP2340506A1 (en) 2011-07-06
CA3152591C (en) 2023-08-29
ES2559758T3 (es) 2016-02-15
GB2478441A (en) 2011-09-07
JP5701212B2 (ja) 2015-04-15
CA3011730C (en) 2022-05-17
GB2478441B (en) 2013-03-27
SI2340506T1 (sl) 2016-02-29
DK2340506T3 (en) 2016-02-08
JP2012502281A (ja) 2012-01-26
EP2340506B1 (en) 2015-11-11
CA2734535A1 (en) 2010-03-18
CN102209968A (zh) 2011-10-05
CA2734535C (en) 2018-08-28
AU2015249113B2 (en) 2017-09-07

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