KR101658347B1 - 폐암 바이오마커 및 그것들의 용도 - Google Patents

폐암 바이오마커 및 그것들의 용도 Download PDF

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KR101658347B1
KR101658347B1 KR1020117005305A KR20117005305A KR101658347B1 KR 101658347 B1 KR101658347 B1 KR 101658347B1 KR 1020117005305 A KR1020117005305 A KR 1020117005305A KR 20117005305 A KR20117005305 A KR 20117005305A KR 101658347 B1 KR101658347 B1 KR 101658347B1
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biomarker
biomarkers
lung cancer
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rti
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KR20110063753A (ko
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래리 골드
마티 스탠튼
에드워드 엔. 브로디
레이첼 엠. 오스트로프
도미닉 지흐
알렉스 에이. 이. 스튜어트
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소마로직, 인크.
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
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    • G06F17/00Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10Complex mathematical operations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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KR1020117005305A 2008-09-09 2009-09-09 폐암 바이오마커 및 그것들의 용도 Active KR101658347B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9559308P 2008-09-09 2008-09-09
US61/095,593 2008-09-09
US15283709P 2009-02-16 2009-02-16
US61/152,837 2009-02-16
PCT/US2009/056399 WO2010030697A1 (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof

Publications (2)

Publication Number Publication Date
KR20110063753A KR20110063753A (ko) 2011-06-14
KR101658347B1 true KR101658347B1 (ko) 2016-09-21

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EP (1) EP2340506B1 (enExample)
JP (1) JP5701212B2 (enExample)
KR (1) KR101658347B1 (enExample)
CN (2) CN102209968B (enExample)
AU (2) AU2009291811B2 (enExample)
CA (3) CA3011730C (enExample)
DK (1) DK2340506T3 (enExample)
ES (1) ES2559758T3 (enExample)
GB (1) GB2478441B (enExample)
HK (1) HK1204062A1 (enExample)
HR (1) HRP20160127T1 (enExample)
MX (1) MX2011002322A (enExample)
SI (1) SI2340506T1 (enExample)
WO (1) WO2010030697A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10359425B2 (en) 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
EP3444359A1 (en) 2009-03-12 2019-02-20 Cancer Prevention And Cure, Ltd. Methods of identification of non-small cell lung cancer
MX355020B (es) * 2010-07-09 2018-04-02 Somalogic Inc Biomarcadores de cancer de pulmon y usos de los mismos.
JP5931874B2 (ja) 2010-08-13 2016-06-08 ソマロジック・インコーポレーテッド 膵癌バイオマーカーおよびその使用
EP2694964B1 (en) * 2011-04-07 2019-06-26 The Scripps Research Institute High-throughput screening for compounds modulating levels of cellular macromolecules
AU2012249288C1 (en) 2011-04-29 2017-12-21 Lung Cancer Proteomics Llc Methods of identification and diagnosis of lung diseases using classification systems and kits thereof
KR101921945B1 (ko) * 2011-10-24 2018-11-26 소마로직, 인크. 폐암 바이오마커 및 그것의 용도
US11913957B2 (en) 2011-12-21 2024-02-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
US9304137B2 (en) 2011-12-21 2016-04-05 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
CA2860298A1 (en) * 2011-12-21 2013-06-27 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
CN104115150B (zh) * 2012-02-17 2018-05-04 皇家飞利浦有限公司 急性肺损伤(ali)/急性呼吸窘迫整合征(ards)评估和监测
WO2014074682A1 (en) 2012-11-07 2014-05-15 Somalogic, Inc. Chronic obstructive pulmonary disease (copd) biomarkers and uses thereof
RU2677742C2 (ru) * 2013-11-07 2019-01-21 Медиал Рисеч Лтд. Способы и системы оценки риска развития злокачественной опухоли легкого
KR102087373B1 (ko) * 2015-09-11 2020-03-10 주식회사 압타머사이언스 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법
FR3050269B1 (fr) * 2016-04-15 2018-05-11 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris (Espci) Procede de selection et de recuperation de produits et systeme associe
CN105823665A (zh) * 2016-05-13 2016-08-03 北京九州柏林生物科技有限公司 生物组织样本制备套液
CN109715830A (zh) * 2016-06-21 2019-05-03 威斯塔解剖学和生物学研究所 用于使用基因表达谱诊断肺癌的组合物和方法
JP6280997B1 (ja) * 2016-10-31 2018-02-14 株式会社Preferred Networks 疾患の罹患判定装置、疾患の罹患判定方法、疾患の特徴抽出装置及び疾患の特徴抽出方法
WO2018187496A2 (en) 2017-04-04 2018-10-11 Lung Cancer Proteomics, Llc Plasma based protein profiling for early stage lung cancer prognosis
WO2019046814A1 (en) 2017-09-01 2019-03-07 Venn Biosciences Corporation IDENTIFICATION AND USE OF GLYCOPEPTIDES AS BIOMARKERS FOR THE DIAGNOSIS AND MONITORING OF TREATMENT
EP3714275A4 (en) * 2017-11-22 2021-10-27 Gritstone bio, Inc. REDUCTION OF JUNCTION EPITOPIC PRESENTATION FOR NEOANTIGENS
WO2019126343A1 (en) 2017-12-19 2019-06-27 The Wistar Institute Of Anatomy And Biology Compositions and methods for diagnosing lung cancers using gene expression profiles
CA3104041A1 (en) * 2018-06-22 2019-12-26 Somalogic, Inc. Improved proteomic multiplex assays
SG11202113075WA (en) * 2019-06-21 2021-12-30 Nat Univ Singapore Methods for determining the likelihood of lung cancer
CN110579611B (zh) * 2019-09-18 2023-01-31 郑州大学 一种用于肺癌早期筛查和诊断的联合检测血清标志物、试剂盒及检测方法
CN111047609B (zh) * 2020-03-13 2020-07-24 北京深睿博联科技有限责任公司 肺炎病灶分割方法和装置
WO2022073502A1 (zh) * 2020-10-10 2022-04-14 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 生物标志物在制备肺癌检测试剂中的用途和方法
CN112557514B (zh) * 2020-12-22 2021-09-21 中国海洋大学 手持式海底沉积物样品剖面声学全自动测量装置
WO2025137139A1 (en) * 2023-12-18 2025-06-26 Caris Mpi, Inc. Dynamic tissue typing

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596503B1 (en) * 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
US20030190602A1 (en) * 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
IL157872A0 (en) * 2001-03-12 2004-03-28 Monogen Inc A panel for detecting a generic disease state containing a plurality of probes and using cell-based diagnosis
AU2002309583A1 (en) * 2001-04-18 2002-11-05 Protein Desing Labs, Inc. Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
EP1573044A4 (en) * 2002-12-18 2006-07-05 Ciphergen Biosystems Inc SERUM BIOMARKERS IN LUNG CANCER
CN1225477C (zh) * 2003-03-28 2005-11-02 上海市疾病预防控制中心 肺癌早期血清特异蛋白及其应用
CN1455257A (zh) * 2003-05-23 2003-11-12 北京师范大学 一种利用表面修饰蛋白芯片进行肺癌诊断方法
JP4938451B2 (ja) * 2004-03-23 2012-05-23 オンコセラピー・サイエンス株式会社 非小細胞肺癌の診断のための方法
JP2005304497A (ja) * 2004-03-25 2005-11-04 Joji Inasawa 特定の癌関連遺伝子を用いる癌の検出方法及び癌の抑制方法
WO2005113798A2 (en) * 2004-04-15 2005-12-01 University Of Florida Research Foundation, Inc. Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining
WO2005103281A2 (en) * 2004-04-26 2005-11-03 Children's Medical Center Corporation Platelet biomarkers for the detection of disease
KR20070043868A (ko) * 2004-08-02 2007-04-25 칠드런'즈 메디컬 센터 코포레이션 암에 대한 혈소판 바이오마커
CN1873417A (zh) * 2005-06-02 2006-12-06 中国医学科学院肿瘤医院肿瘤研究所 一种用于诊断肺癌的蛋白质芯片
ES2606015T3 (es) * 2005-12-22 2017-03-17 Abbott Molecular Inc. Métodos y combinaciones de marcadores para la detección de la predisposición al cáncer de pulmón
US7908091B2 (en) * 2006-03-17 2011-03-15 Prometheus Laboratories Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy
WO2008048119A2 (en) * 2006-10-17 2008-04-24 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
WO2008097908A2 (en) * 2007-02-05 2008-08-14 Dana-Farber Cancer Institute, Inc. Methods of diagnosing and prognosing lung cancer
KR100846354B1 (ko) * 2007-03-21 2008-07-15 (주) 프로탄바이오 혈청 당단백질부터 분리한 폐암 진단용 마커
CA2684945A1 (en) * 2007-05-18 2008-11-27 University Of Southern California Germline polymorphisms in the angiogenic pathway predict tumor recurrence in cancer therapy
US7888051B2 (en) * 2007-09-11 2011-02-15 Cancer Prevention And Cure, Ltd. Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues
WO2010003772A1 (en) * 2008-06-16 2010-01-14 Siemens Medical Solutions Diagnostics Gmbh Method for predicting adverse response to erythropoietin in breast cancer treatment
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
JP6114035B2 (ja) * 2010-02-10 2017-04-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 肺癌検出用唾液バイオマーカー

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Publication number Publication date
KR20110063753A (ko) 2011-06-14
SI2340506T1 (sl) 2016-02-29
GB201106053D0 (en) 2011-05-25
CN102209968B (zh) 2016-05-04
GB2478441A (en) 2011-09-07
CA2734535C (en) 2018-08-28
CA3152591C (en) 2023-08-29
WO2010030697A1 (en) 2010-03-18
AU2015249113B2 (en) 2017-09-07
CA3011730A1 (en) 2010-03-18
CN104198709A (zh) 2014-12-10
AU2009291811B2 (en) 2015-10-29
AU2015249113A1 (en) 2015-11-12
GB2478441B (en) 2013-03-27
HK1153834A1 (en) 2012-04-05
HK1204062A1 (zh) 2015-11-06
HRP20160127T1 (hr) 2016-03-11
CA3152591A1 (en) 2010-03-18
JP5701212B2 (ja) 2015-04-15
EP2340506A4 (en) 2012-02-15
CA3011730C (en) 2022-05-17
CN102209968A (zh) 2011-10-05
CA2734535A1 (en) 2010-03-18
ES2559758T3 (es) 2016-02-15
EP2340506B1 (en) 2015-11-11
JP2012502281A (ja) 2012-01-26
MX2011002322A (es) 2011-05-10
AU2009291811A1 (en) 2010-03-18
EP2340506A1 (en) 2011-07-06
DK2340506T3 (en) 2016-02-08

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