CA3149309A1 - Bispecific antibody - Google Patents
Bispecific antibody Download PDFInfo
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- CA3149309A1 CA3149309A1 CA3149309A CA3149309A CA3149309A1 CA 3149309 A1 CA3149309 A1 CA 3149309A1 CA 3149309 A CA3149309 A CA 3149309A CA 3149309 A CA3149309 A CA 3149309A CA 3149309 A1 CA3149309 A1 CA 3149309A1
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C—CHEMISTRY; METALLURGY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
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- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019-139751 | 2019-07-30 | ||
| JP2019139751 | 2019-07-30 | ||
| PCT/JP2020/028972 WO2021020416A1 (ja) | 2019-07-30 | 2020-07-29 | 二重特異性抗体 |
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| Publication Number | Publication Date |
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| CA3149309A1 true CA3149309A1 (en) | 2021-02-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3149309A Pending CA3149309A1 (en) | 2019-07-30 | 2020-07-29 | Bispecific antibody |
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| EP (1) | EP4008348A4 (enExample) |
| JP (2) | JP6856183B1 (enExample) |
| KR (1) | KR20220039720A (enExample) |
| CN (1) | CN114174343A (enExample) |
| AU (1) | AU2020322765A1 (enExample) |
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| CA (1) | CA3149309A1 (enExample) |
| IL (1) | IL290050A (enExample) |
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| TW (1) | TW202118790A (enExample) |
| WO (1) | WO2021020416A1 (enExample) |
| ZA (1) | ZA202201247B (enExample) |
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| TWI804572B (zh) * | 2018-02-09 | 2023-06-11 | 日商小野藥品工業股份有限公司 | 雙特異性抗體 |
| CN120752054A (zh) | 2023-03-16 | 2025-10-03 | 小野药品工业株式会社 | 抗体制剂 |
Family Cites Families (49)
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| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4801687A (en) | 1986-10-27 | 1989-01-31 | Bioprobe International, Inc. | Monoclonal antibody purification process using protein A |
| FI884924L (fi) | 1987-10-28 | 1989-04-29 | Oncogen | Humanimmuglobulin som producerats med hybrid-dna-teknik. |
| US5476996A (en) | 1988-06-14 | 1995-12-19 | Lidak Pharmaceuticals | Human immune system in non-human animal |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5151504A (en) | 1989-11-17 | 1992-09-29 | E. R. Squibb & Sons, Inc. | Method for purification of monoclonal antibodies |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
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| JP2004072286A (ja) | 2002-08-05 | 2004-03-04 | Nippon Telegr & Teleph Corp <Ntt> | 構造変化検出方法および通信網異常状態検出方法、並びに、その装置およびプログラム |
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| US10358492B2 (en) | 2012-09-27 | 2019-07-23 | Merus N.V. | Bispecific IgG antibodies as T cell engagers |
| EP3345928B1 (en) * | 2015-07-10 | 2020-06-24 | Merus N.V. | Human cd3 binding antibody |
| EP3353210B8 (en) * | 2015-09-25 | 2024-12-18 | F. Hoffmann-La Roche AG | Anti-tigit antibodies and methods of use |
| MX2019014577A (es) * | 2017-06-05 | 2020-07-29 | Janssen Biotech Inc | Anticuerpos que se unen especificamente a pd-1 y metodos de uso. |
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| TWI804572B (zh) * | 2018-02-09 | 2023-06-11 | 日商小野藥品工業股份有限公司 | 雙特異性抗體 |
-
2020
- 2020-07-29 BR BR112022001473A patent/BR112022001473A2/pt not_active IP Right Cessation
- 2020-07-29 CA CA3149309A patent/CA3149309A1/en active Pending
- 2020-07-29 US US17/630,426 patent/US20220281977A1/en active Pending
- 2020-07-29 CN CN202080054077.0A patent/CN114174343A/zh active Pending
- 2020-07-29 WO PCT/JP2020/028972 patent/WO2021020416A1/ja not_active Ceased
- 2020-07-29 AU AU2020322765A patent/AU2020322765A1/en not_active Abandoned
- 2020-07-29 MX MX2022000971A patent/MX2022000971A/es unknown
- 2020-07-29 KR KR1020227003026A patent/KR20220039720A/ko not_active Abandoned
- 2020-07-29 PH PH1/2022/550190A patent/PH12022550190A1/en unknown
- 2020-07-29 TW TW109125604A patent/TW202118790A/zh unknown
- 2020-07-29 JP JP2020570992A patent/JP6856183B1/ja active Active
- 2020-07-29 EP EP20846826.4A patent/EP4008348A4/en active Pending
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2021
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2022
- 2022-01-23 IL IL290050A patent/IL290050A/en unknown
- 2022-01-26 ZA ZA2022/01247A patent/ZA202201247B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2021020416A1 (ja) | 2021-09-13 |
| CN114174343A (zh) | 2022-03-11 |
| WO2021020416A1 (ja) | 2021-02-04 |
| JP6856183B1 (ja) | 2021-04-07 |
| EP4008348A1 (en) | 2022-06-08 |
| JP2021075580A (ja) | 2021-05-20 |
| AU2020322765A1 (en) | 2022-02-24 |
| BR112022001473A2 (pt) | 2022-03-22 |
| US20220281977A1 (en) | 2022-09-08 |
| ZA202201247B (en) | 2023-08-30 |
| TW202118790A (zh) | 2021-05-16 |
| MX2022000971A (es) | 2022-02-14 |
| JP7574692B2 (ja) | 2024-10-29 |
| PH12022550190A1 (en) | 2022-11-21 |
| KR20220039720A (ko) | 2022-03-29 |
| IL290050A (en) | 2022-03-01 |
| EP4008348A4 (en) | 2023-11-15 |
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