CA3147770A1 - Analogue d'exenatide et son utilisation - Google Patents
Analogue d'exenatide et son utilisation Download PDFInfo
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- CA3147770A1 CA3147770A1 CA3147770A CA3147770A CA3147770A1 CA 3147770 A1 CA3147770 A1 CA 3147770A1 CA 3147770 A CA3147770 A CA 3147770A CA 3147770 A CA3147770 A CA 3147770A CA 3147770 A1 CA3147770 A1 CA 3147770A1
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- aci
- exenati
- anal
- ami
- agm
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- A—HUMAN NECESSITIES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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Abstract
La présente invention concerne un analogue d'exénatide glycosylé en un résidu spécifique et son utilisation. La présente invention concerne une nouvelle substance pour le traitement du diabète, la nouvelle substance présentant une stabilité in vivo améliorée par comparaison avec des exénatides classiques et leurs analogues. La présente invention concerne un analogue de dimère d'exénatide et son utilisation. La présente invention concerne une nouvelle substance pour le traitement du diabète et de l'obésité, la nouvelle substance présentant une stabilité in vivo significativement améliorée par comparaison avec des exénatides classiques et leurs analogues.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20190098911 | 2019-08-13 | ||
| KR10-2019-0098911 | 2019-08-13 | ||
| KR1020200101087A KR102493143B1 (ko) | 2019-08-13 | 2020-08-12 | 당쇄화 엑세나타이드 유사체 및 이의 용도 |
| KR10-2020-0101087 | 2020-08-12 | ||
| KR1020200101088A KR102419566B1 (ko) | 2019-08-13 | 2020-08-12 | 엑세나타이드 이량 유사체 및 이의 용도 |
| KR10-2020-0101088 | 2020-08-12 | ||
| PCT/KR2020/010751 WO2021029698A1 (fr) | 2019-08-13 | 2020-08-13 | Analogue d'exénatide et son utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3147770A1 true CA3147770A1 (fr) | 2021-02-18 |
Family
ID=74569484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3147770A Pending CA3147770A1 (fr) | 2019-08-13 | 2020-08-13 | Analogue d'exenatide et son utilisation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220323548A1 (fr) |
| EP (1) | EP4015528A4 (fr) |
| JP (1) | JP7425855B2 (fr) |
| CN (1) | CN115380043A (fr) |
| CA (1) | CA3147770A1 (fr) |
| WO (1) | WO2021029698A1 (fr) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5107713B2 (ja) * | 2004-10-07 | 2012-12-26 | ノヴォ ノルディスク アー／エス | 遅延性のエキセンディン−４化合物 |
| JP2008533104A (ja) * | 2005-03-18 | 2008-08-21 | ノボ ノルディスク アクティーゼルスカブ | Ｇｌｐ−１受容体の二量体ペプチドアゴニスト |
| TWI423821B (zh) * | 2007-06-19 | 2014-01-21 | Glucose-containing glucagon-like peptide-1 peptide | |
| US8703701B2 (en) * | 2009-12-18 | 2014-04-22 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
| EP2528618A4 (fr) * | 2010-01-27 | 2015-05-27 | Univ Indiana Res & Tech Corp | Conjugués d'antagoniste du glucagon et d'agoniste du gip et compositions pour le traitement de troubles métaboliques et de l'obésité |
| CA2792663A1 (fr) * | 2010-03-26 | 2011-09-29 | Novo Nordisk A/S | Nouveaux analogues du glucagon |
| UA116217C2 (uk) * | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| US10077319B2 (en) | 2014-02-21 | 2018-09-18 | Medimmune, Llc | Anti-PCSK9-GLP-1 fusions and methods for use |
| KR101768446B1 (ko) | 2014-03-21 | 2017-08-17 | 애니젠 주식회사 | 신규한 엑세나타이드 유사체 및 그의 용도 |
| CN107106680A (zh) | 2014-11-13 | 2017-08-29 | 江苏奥赛康药业股份有限公司 | 具备双受体激动剂活性的融合蛋白 |
| JP2019139182A (ja) | 2018-02-15 | 2019-08-22 | 株式会社ディスコ | 液晶パネルの製造方法 |
| KR20200101088A (ko) | 2019-02-19 | 2020-08-27 | (주) 엠센트 코리아 | 발향장치 |
| KR20200101087A (ko) | 2019-02-19 | 2020-08-27 | 김형구 | 조리용 집게 |
| CN111410686B (zh) * | 2020-03-18 | 2021-02-26 | 南京枫璟生物医药科技有限公司 | Glp-1r激活剂的分子改构及其二聚体在治疗代谢病中的应用 |
-
2020
- 2020-08-13 CA CA3147770A patent/CA3147770A1/fr active Pending
- 2020-08-13 WO PCT/KR2020/010751 patent/WO2021029698A1/fr unknown
- 2020-08-13 CN CN202080057405.2A patent/CN115380043A/zh active Pending
- 2020-08-13 EP EP20852849.7A patent/EP4015528A4/fr active Pending
- 2020-08-13 US US17/635,039 patent/US20220323548A1/en active Pending
- 2020-08-13 JP JP2022509115A patent/JP7425855B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20220323548A1 (en) | 2022-10-13 |
| EP4015528A4 (fr) | 2023-09-20 |
| JP2022544556A (ja) | 2022-10-19 |
| WO2021029698A1 (fr) | 2021-02-18 |
| EP4015528A1 (fr) | 2022-06-22 |
| JP7425855B2 (ja) | 2024-01-31 |
| CN115380043A (zh) | 2022-11-22 |
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