CA3126476A1 - Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors - Google Patents

Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors Download PDF

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Publication number
CA3126476A1
CA3126476A1 CA3126476A CA3126476A CA3126476A1 CA 3126476 A1 CA3126476 A1 CA 3126476A1 CA 3126476 A CA3126476 A CA 3126476A CA 3126476 A CA3126476 A CA 3126476A CA 3126476 A1 CA3126476 A1 CA 3126476A1
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Prior art keywords
seq
angptl7
nucleic acid
position corresponding
acid molecule
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Pending
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CA3126476A
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English (en)
French (fr)
Inventor
Kavita PRAVEEN
Claudia SCHURMANN
Lauren GURSKI
Tanya Teslovich Dostal
Goncalo Abecasis
Aris BARAS
Giovanni Coppola
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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Publication of CA3126476A1 publication Critical patent/CA3126476A1/en
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3126476A 2019-01-23 2020-01-21 Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors Pending CA3126476A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962795665P 2019-01-23 2019-01-23
US62/795,665 2019-01-23
US201962880609P 2019-07-30 2019-07-30
US62/880,609 2019-07-30
US201962902683P 2019-09-19 2019-09-19
US62/902,683 2019-09-19
US201962909573P 2019-10-02 2019-10-02
US62/909,573 2019-10-02
PCT/US2020/014373 WO2020154268A2 (en) 2019-01-23 2020-01-21 Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors

Publications (1)

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CA3126476A1 true CA3126476A1 (en) 2020-07-30

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CA3126476A Pending CA3126476A1 (en) 2019-01-23 2020-01-21 Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors

Country Status (11)

Country Link
US (2) US11767526B2 (https=)
EP (1) EP3914711A2 (https=)
JP (2) JP2022523301A (https=)
KR (1) KR20210132045A (https=)
CN (1) CN113646432A (https=)
AU (1) AU2020210630C1 (https=)
CA (1) CA3126476A1 (https=)
IL (1) IL284700B2 (https=)
MX (1) MX2021008797A (https=)
SG (1) SG11202107497XA (https=)
WO (1) WO2020154268A2 (https=)

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JP2022523301A (ja) 2022-04-22
US11767526B2 (en) 2023-09-26
SG11202107497XA (en) 2021-08-30
IL284700A (en) 2021-08-31
AU2020210630A1 (en) 2021-08-05
WO2020154268A2 (en) 2020-07-30
US11512309B2 (en) 2022-11-29
US20200231965A1 (en) 2020-07-23
WO2020154268A9 (en) 2021-09-16
IL284700B1 (en) 2025-06-01
WO2020154268A3 (en) 2020-09-24
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KR20210132045A (ko) 2021-11-03
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AU2020210630C1 (en) 2026-04-09
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