MX2021008797A - Tratamiento de afecciones oftalmicas con inhibidores de proteinas relacionadas a angiopoyetina 7 (angptl7). - Google Patents
Tratamiento de afecciones oftalmicas con inhibidores de proteinas relacionadas a angiopoyetina 7 (angptl7).Info
- Publication number
- MX2021008797A MX2021008797A MX2021008797A MX2021008797A MX2021008797A MX 2021008797 A MX2021008797 A MX 2021008797A MX 2021008797 A MX2021008797 A MX 2021008797A MX 2021008797 A MX2021008797 A MX 2021008797A MX 2021008797 A MX2021008797 A MX 2021008797A
- Authority
- MX
- Mexico
- Prior art keywords
- angptl7
- variant
- angiopoietin
- inhibitors
- treatment
- Prior art date
Links
- 102100034598 Angiopoietin-related protein 7 Human genes 0.000 title 1
- 101000924546 Homo sapiens Angiopoietin-related protein 7 Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000009840 Angiopoietins Human genes 0.000 abstract 1
- 108010009906 Angiopoietins Proteins 0.000 abstract 1
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
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- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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- C12Q2600/00—Oligonucleotides characterized by their use
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- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
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- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962795665P | 2019-01-23 | 2019-01-23 | |
| US201962880609P | 2019-07-30 | 2019-07-30 | |
| US201962902683P | 2019-09-19 | 2019-09-19 | |
| US201962909573P | 2019-10-02 | 2019-10-02 | |
| PCT/US2020/014373 WO2020154268A2 (en) | 2019-01-23 | 2020-01-21 | Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021008797A true MX2021008797A (es) | 2022-01-31 |
Family
ID=69591771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021008797A MX2021008797A (es) | 2019-01-23 | 2020-01-21 | Tratamiento de afecciones oftalmicas con inhibidores de proteinas relacionadas a angiopoyetina 7 (angptl7). |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11767526B2 (https=) |
| EP (1) | EP3914711A2 (https=) |
| JP (2) | JP2022523301A (https=) |
| KR (1) | KR20210132045A (https=) |
| CN (1) | CN113646432A (https=) |
| AU (1) | AU2020210630C1 (https=) |
| CA (1) | CA3126476A1 (https=) |
| IL (1) | IL284700B2 (https=) |
| MX (1) | MX2021008797A (https=) |
| SG (1) | SG11202107497XA (https=) |
| WO (1) | WO2020154268A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11845989B2 (en) | 2019-01-23 | 2023-12-19 | Regeneron Pharmaceuticals, Inc. | Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors |
| JP2022523301A (ja) | 2019-01-23 | 2022-04-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | アンジオポエチン様7(angptl7)阻害剤による眼疾患の治療 |
| KR20220024153A (ko) | 2019-05-24 | 2022-03-03 | 엠피리코 인크. | 안지오포이에틴 유사 7(angptl7) 관련 질환의 치료 |
| WO2022072356A1 (en) * | 2020-09-29 | 2022-04-07 | Empirico Inc. | Compositions and methods for the treatment of angiopoietin like 7 (angptl7) related diseases |
| EP4251753A4 (en) * | 2020-11-24 | 2025-08-06 | Empirico Inc | TREATMENT OF DISEASES AND DISORDERS RELATED TO SOS2 |
| WO2022182768A1 (en) * | 2021-02-26 | 2022-09-01 | Regeneron Pharmaceuticals, Inc. | Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors |
| EP4408535A1 (en) * | 2021-09-30 | 2024-08-07 | Regeneron Pharmaceuticals, Inc. | Treatment of glaucoma with rho guanine nucleotide exchange factor 12 (arhgef12) inhibitors |
| US20240409943A1 (en) * | 2021-10-01 | 2024-12-12 | Alnylam Pharmaceuticals, Inc. | iRNA Compositions and Methods for Targeting ANGPTL7 |
| IL313191A (en) * | 2021-12-22 | 2024-07-01 | Regeneron Pharma | Treatment of kidney diseases using angiopoietin-like inhibitors 3 |
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| US20100028875A1 (en) | 2006-07-05 | 2010-02-04 | Mun-Gan Rhyu | Method for diagnosing cancer by detecting the methylation of transitional zones |
| AU2010247800A1 (en) | 2009-05-11 | 2011-12-15 | Berg Llc | Methods for the diagnosis of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers |
| CN102497884A (zh) | 2009-07-27 | 2012-06-13 | 巴克斯特国际公司 | 凝血蛋白缀合物 |
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| JP2018164442A (ja) * | 2017-03-28 | 2018-10-25 | 国立大学法人 熊本大学 | 皮膚有棘細胞癌の判定、予防又は治療方法 |
| JP6779164B2 (ja) * | 2017-03-28 | 2020-11-04 | ヤンマーパワーテクノロジー株式会社 | 作業車両の自律走行システム |
| CA3065317A1 (en) | 2017-05-31 | 2018-12-06 | Commonwealth Scientific And Industrial Research Organisation | Trait selection in avians |
| WO2019140380A1 (en) | 2018-01-12 | 2019-07-18 | Kymera Therapeutics, Inc. | Protein degraders and uses thereof |
| EP3740224A4 (en) | 2018-01-18 | 2022-05-04 | Adanate, Inc. | ANTI-LILRB ANTIBODIES AND THEIR USES |
| GB201806118D0 (en) | 2018-04-13 | 2018-05-30 | Univ Edinburgh | Macrophage use |
| JP2022523301A (ja) | 2019-01-23 | 2022-04-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | アンジオポエチン様7(angptl7)阻害剤による眼疾患の治療 |
| KR20220024153A (ko) | 2019-05-24 | 2022-03-03 | 엠피리코 인크. | 안지오포이에틴 유사 7(angptl7) 관련 질환의 치료 |
| WO2022072356A1 (en) | 2020-09-29 | 2022-04-07 | Empirico Inc. | Compositions and methods for the treatment of angiopoietin like 7 (angptl7) related diseases |
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| CA3126476A1 (en) | 2020-07-30 |
| IL284700B2 (en) | 2025-10-01 |
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| SG11202107497XA (en) | 2021-08-30 |
| IL284700A (en) | 2021-08-31 |
| AU2020210630A1 (en) | 2021-08-05 |
| WO2020154268A2 (en) | 2020-07-30 |
| US11512309B2 (en) | 2022-11-29 |
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| WO2020154268A9 (en) | 2021-09-16 |
| IL284700B1 (en) | 2025-06-01 |
| WO2020154268A3 (en) | 2020-09-24 |
| KR20210132045A (ko) | 2021-11-03 |
| US20210277391A1 (en) | 2021-09-09 |
| AU2020210630C1 (en) | 2026-04-09 |
| CN113646432A (zh) | 2021-11-12 |
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