CA3113147C - Hemoglobines recombinantes et leurs procedes de preparation et d'utilisation - Google Patents
Hemoglobines recombinantes et leurs procedes de preparation et d'utilisation Download PDFInfo
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- CA3113147C CA3113147C CA3113147A CA3113147A CA3113147C CA 3113147 C CA3113147 C CA 3113147C CA 3113147 A CA3113147 A CA 3113147A CA 3113147 A CA3113147 A CA 3113147A CA 3113147 C CA3113147 C CA 3113147C
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Psychology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cardiology (AREA)
Abstract
L'invention concerne des hémoglobines recombinantes ayant une capacité de transport d'oxygène améliorée et des procédés de préparation et d'utilisation de celles-ci. L'invention concerne également une composition pharmaceutique comprenant l'hémoglobine recombinante utile pour traiter des maladies ou des états liés à une déficience en oxygène, tels qu'un accident vasculaire cérébral, un choc hémorragique, une maladie artérielle périphérique (PAD), le mal de montagne aigu (AMS), le cancer et la maladie de Parkinson (PD).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962799829P | 2019-02-01 | 2019-02-01 | |
| US62/799,829 | 2019-02-01 | ||
| PCT/CN2020/074173 WO2020156556A1 (fr) | 2019-02-01 | 2020-02-03 | Hémoglobines recombinantes et leurs procédés de préparation et d'utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3113147A1 CA3113147A1 (fr) | 2020-08-06 |
| CA3113147C true CA3113147C (fr) | 2022-03-08 |
Family
ID=71837799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3113147A Active CA3113147C (fr) | 2019-02-01 | 2020-02-03 | Hemoglobines recombinantes et leurs procedes de preparation et d'utilisation |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10752672B1 (fr) |
| EP (1) | EP3837280A4 (fr) |
| JP (1) | JP7066067B2 (fr) |
| KR (1) | KR102436043B1 (fr) |
| CN (1) | CN113166230A (fr) |
| AU (1) | AU2020214952B2 (fr) |
| CA (1) | CA3113147C (fr) |
| NZ (1) | NZ774144A (fr) |
| WO (1) | WO2020156556A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114786705B (zh) * | 2019-12-06 | 2023-05-12 | 环喜有限公司 | 治疗炎症性肠病的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6022849A (en) * | 1987-05-16 | 2000-02-08 | Baxter Biotech Technology Saarl | Mutant recombinant hemoglobins containing heme pocket mutations |
| IL94361A (en) * | 1989-05-10 | 1995-07-31 | Somatogenetics Int | Polypeptides, recombinant AND molecules and a method for the production of human hemoglobin-like protein |
| US5545727A (en) * | 1989-05-10 | 1996-08-13 | Somatogen, Inc. | DNA encoding fused di-alpha globins and production of pseudotetrameric hemoglobin |
| US5599907A (en) * | 1989-05-10 | 1997-02-04 | Somatogen, Inc. | Production and use of multimeric hemoglobins |
| EP0979279B1 (fr) | 1997-05-02 | 2008-03-19 | Baxter Biotech Technology S.A.R.L. | Mutants d'hemoglobine avec evacuation reduite d'oxyde nitrique |
| EP1950298A3 (fr) * | 1997-05-02 | 2008-12-24 | Baxter Biotech Technology S.A.R.L. | Mutants d'hémoglobine dotés d'une expression soluble accrue et/ou d'une évacuation réduite de l'oxyde nitrique |
| AU784195B2 (en) * | 1999-11-12 | 2006-02-16 | Baxter Biotech Technology S.A.R.L. | Reduced side-effect hemoglobin compositions |
| US9814759B2 (en) * | 2014-07-02 | 2017-11-14 | Cheer Global Ltd. | Pharmaceutical composition comprising recombinant hemoglobin protein or subunit-based therapeutic agent for cancer targeting treatment |
| US10946099B2 (en) | 2017-06-27 | 2021-03-16 | Vision Global Holdings Limited | Compositions for photodynamic therapy and fluorescence diagnosis of cancers and other diseases |
-
2020
- 2020-01-31 US US16/777,932 patent/US10752672B1/en active Active
- 2020-02-03 WO PCT/CN2020/074173 patent/WO2020156556A1/fr unknown
- 2020-02-03 NZ NZ774144A patent/NZ774144A/en unknown
- 2020-02-03 KR KR1020217024807A patent/KR102436043B1/ko active IP Right Grant
- 2020-02-03 CN CN202080006276.4A patent/CN113166230A/zh active Pending
- 2020-02-03 EP EP20747899.1A patent/EP3837280A4/fr active Pending
- 2020-02-03 JP JP2021544764A patent/JP7066067B2/ja active Active
- 2020-02-03 AU AU2020214952A patent/AU2020214952B2/en active Active
- 2020-02-03 CA CA3113147A patent/CA3113147C/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2020214952B2 (en) | 2022-03-03 |
| KR102436043B1 (ko) | 2022-08-23 |
| CN113166230A (zh) | 2021-07-23 |
| EP3837280A4 (fr) | 2022-05-18 |
| JP7066067B2 (ja) | 2022-05-12 |
| US10752672B1 (en) | 2020-08-25 |
| KR20210130712A (ko) | 2021-11-01 |
| NZ774144A (en) | 2022-02-25 |
| WO2020156556A1 (fr) | 2020-08-06 |
| EP3837280A1 (fr) | 2021-06-23 |
| JP2022515560A (ja) | 2022-02-18 |
| US20200247877A1 (en) | 2020-08-06 |
| AU2020214952A1 (en) | 2021-08-19 |
| CA3113147A1 (fr) | 2020-08-06 |
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