CA3079697A1 - Transdermal therapeutic system for the transdermal administration of guanfacine comprising at least one additive - Google Patents
Transdermal therapeutic system for the transdermal administration of guanfacine comprising at least one additive Download PDFInfo
- Publication number
- CA3079697A1 CA3079697A1 CA3079697A CA3079697A CA3079697A1 CA 3079697 A1 CA3079697 A1 CA 3079697A1 CA 3079697 A CA3079697 A CA 3079697A CA 3079697 A CA3079697 A CA 3079697A CA 3079697 A1 CA3079697 A1 CA 3079697A1
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- CA
- Canada
- Prior art keywords
- guanfacine
- weight
- containing layer
- amount
- silicone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762570745P | 2017-10-11 | 2017-10-11 | |
US62/570,745 | 2017-10-11 | ||
EP17205546.9 | 2017-12-05 | ||
EP17205546 | 2017-12-05 | ||
PCT/EP2018/077792 WO2019072998A1 (en) | 2017-10-11 | 2018-10-11 | TRANSDERMAL THERAPEUTIC SYSTEM FOR TRANSDERMAL DELIVERY OF GUANFACIN HAVING AT LEAST ONE ADDITIVE |
Publications (1)
Publication Number | Publication Date |
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CA3079697A1 true CA3079697A1 (en) | 2019-04-18 |
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CA3079697A Pending CA3079697A1 (en) | 2017-10-11 | 2018-10-11 | Transdermal therapeutic system for the transdermal administration of guanfacine comprising at least one additive |
Country Status (11)
Country | Link |
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US (1) | US20200397715A1 (ko) |
EP (1) | EP3694498A1 (ko) |
JP (1) | JP7445218B2 (ko) |
KR (1) | KR20200070306A (ko) |
CN (1) | CN111447926B (ko) |
AU (1) | AU2018348802A1 (ko) |
BR (1) | BR112020007011A2 (ko) |
CA (1) | CA3079697A1 (ko) |
MX (1) | MX2020003665A (ko) |
TW (1) | TWI829654B (ko) |
WO (1) | WO2019072998A1 (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3079696A1 (en) | 2017-10-11 | 2019-04-18 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system for the transdermal administration of guanfacine comprising a silicone polymer |
EP4395749A1 (en) * | 2021-08-30 | 2024-07-10 | LTS Lohmann Therapie-Systeme AG | Transdermal therapeutic system for the transdermal administration of guanfacine comprising guanfacine and a mono-carboxylic acid |
WO2024040897A1 (zh) * | 2022-08-24 | 2024-02-29 | 新领医药技术(深圳)有限公司 | 沙利度胺或其类似物透皮贴剂及其制备方法 |
Family Cites Families (14)
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JPS62289514A (ja) * | 1986-04-03 | 1987-12-16 | ハ−コン ラボラトリ−ズ コ−ポレ−シヨン | 薬理活性物質を経皮、経口又は皮下移植により投与する為の製品 |
JPH01265021A (ja) * | 1987-10-29 | 1989-10-23 | Hercon Lab Corp | 薬理学的活性物質を含有する組成物を動物組織に制御放出および供給するための物品 |
US5028431A (en) * | 1987-10-29 | 1991-07-02 | Hercon Laboratories Corporation | Article for the delivery to animal tissue of a pharmacologically active agent |
US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
US5762952A (en) * | 1993-04-27 | 1998-06-09 | Hercon Laboratories Corporation | Transdermal delivery of active drugs |
JPH07145048A (ja) * | 1993-11-25 | 1995-06-06 | Sekisui Chem Co Ltd | 医療用貼付剤 |
DE69922257T2 (de) * | 1998-07-29 | 2005-11-10 | Teijin Ltd. | Druckempfindliche klebstoffzusammensetzung und feuchtigkeitsdurchlässiges, druckempfindliches klebeband, druckempfindliche, pharmazeutische klebstoffzusammensetzung und herstellung eines druckempfindlichen klebebandes welches diese zusammensetzung enthält |
CN100411692C (zh) * | 2004-01-13 | 2008-08-20 | 北京康倍得医药技术开发有限公司 | 丙烯酸基粘合剂组合物及其药物组合物和透皮治疗系统 |
KR101432698B1 (ko) | 2006-06-06 | 2014-08-22 | 다우 코닝 코포레이션 | 실리콘 아크릴레이트 하이브리드 조성물 |
BRPI1014886B1 (pt) | 2009-04-24 | 2020-02-11 | Henkel IP & Holding GmbH | Polímeros acrílicos de silicone híbridos, seus métodos de preparação, adesivos e soluções de uma composição adesiva sensível à pressão compreendendo os mesmos. |
JP2013139554A (ja) | 2011-11-29 | 2013-07-18 | Dow Corning Corp | シリコーンアクリレートハイブリッド組成物及び該組成物の製造方法 |
CA2896055C (en) * | 2012-12-28 | 2021-02-16 | Noven Pharmaceuticals, Inc. | Compositions and methods for transdermal delivery of amphetamine and clonidine |
WO2016130408A1 (en) | 2015-02-09 | 2016-08-18 | Dow Corning Corporation | Multi-phase silicone acrylic hybrid visco-elastic compositions and methods of making same |
EP3349737A4 (en) * | 2015-09-14 | 2019-05-15 | Amneal Pharmaceuticals LLC | SYSTEM FOR TRANSDERING |
-
2018
- 2018-10-11 CA CA3079697A patent/CA3079697A1/en active Pending
- 2018-10-11 MX MX2020003665A patent/MX2020003665A/es unknown
- 2018-10-11 EP EP18788719.5A patent/EP3694498A1/en active Pending
- 2018-10-11 US US16/755,049 patent/US20200397715A1/en active Pending
- 2018-10-11 AU AU2018348802A patent/AU2018348802A1/en active Pending
- 2018-10-11 BR BR112020007011-4A patent/BR112020007011A2/pt unknown
- 2018-10-11 WO PCT/EP2018/077792 patent/WO2019072998A1/en unknown
- 2018-10-11 TW TW107135749A patent/TWI829654B/zh active
- 2018-10-11 KR KR1020207013347A patent/KR20200070306A/ko not_active Application Discontinuation
- 2018-10-11 CN CN201880066613.1A patent/CN111447926B/zh active Active
- 2018-10-11 JP JP2020519801A patent/JP7445218B2/ja active Active
Also Published As
Publication number | Publication date |
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EP3694498A1 (en) | 2020-08-19 |
JP2020536882A (ja) | 2020-12-17 |
CN111447926B (zh) | 2024-04-30 |
AU2018348802A1 (en) | 2020-04-16 |
JP7445218B2 (ja) | 2024-03-07 |
US20200397715A1 (en) | 2020-12-24 |
BR112020007011A2 (pt) | 2020-10-06 |
TW201927295A (zh) | 2019-07-16 |
KR20200070306A (ko) | 2020-06-17 |
RU2020115562A3 (ko) | 2022-02-10 |
CN111447926A (zh) | 2020-07-24 |
RU2020115562A (ru) | 2021-11-15 |
TWI829654B (zh) | 2024-01-21 |
MX2020003665A (es) | 2020-10-01 |
WO2019072998A1 (en) | 2019-04-18 |
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