CA3042067C - Implants and biodegradable fiducial markers - Google Patents
Implants and biodegradable fiducial markers Download PDFInfo
- Publication number
- CA3042067C CA3042067C CA3042067A CA3042067A CA3042067C CA 3042067 C CA3042067 C CA 3042067C CA 3042067 A CA3042067 A CA 3042067A CA 3042067 A CA3042067 A CA 3042067A CA 3042067 C CA3042067 C CA 3042067C
- Authority
- CA
- Canada
- Prior art keywords
- hydrogel
- hydrogel implant
- implant according
- precursors
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
- A61K49/0414—Particles, beads, capsules or spheres
- A61K49/0419—Microparticles, microbeads, microcapsules, microspheres, i.e. having a size or diameter higher or equal to 1 micrometer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Dispersion Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Prostheses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA3149284A CA3149284C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28645009P | 2009-12-15 | 2009-12-15 | |
| US61/286450 | 2009-12-15 | ||
| CA2782899A CA2782899C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2782899A Division CA2782899C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3149284A Division CA3149284C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3042067A1 CA3042067A1 (en) | 2011-07-14 |
| CA3042067C true CA3042067C (en) | 2022-10-18 |
Family
ID=44143217
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3042067A Active CA3042067C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
| CA3149284A Active CA3149284C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
| CA2782899A Active CA2782899C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3149284A Active CA3149284C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
| CA2782899A Active CA2782899C (en) | 2009-12-15 | 2010-12-15 | Implants and biodegradable fiducial markers |
Country Status (8)
| Country | Link |
|---|---|
| US (12) | US8383161B2 (enExample) |
| EP (3) | EP3960215B1 (enExample) |
| JP (1) | JP5820815B2 (enExample) |
| CN (1) | CN102844054B (enExample) |
| AU (1) | AU2010340067B2 (enExample) |
| CA (3) | CA3042067C (enExample) |
| IN (1) | IN2012DN05177A (enExample) |
| WO (1) | WO2011084465A2 (enExample) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10675298B2 (en) * | 2006-07-27 | 2020-06-09 | Boston Scientific Scimed Inc. | Particles |
| EP3960215B1 (en) | 2009-12-15 | 2024-10-16 | Incept, LLC | Implants and biodegradable fiducial markers |
| US10226417B2 (en) | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
| US9205150B2 (en) | 2011-12-05 | 2015-12-08 | Incept, Llc | Medical organogel processes and compositions |
| CA2861048C (en) * | 2012-01-24 | 2021-01-12 | Lifecell Corporation | Elongated tissue matrices |
| US9798856B2 (en) * | 2012-03-21 | 2017-10-24 | Koninklijke Philips N.V. | Clinical workstation integrating medical imaging and biopsy data and methods using same |
| US9226797B2 (en) * | 2012-11-04 | 2016-01-05 | Miba Medical Inc. | Computer aided implantation of body implants |
| WO2014169301A1 (en) * | 2013-04-12 | 2014-10-16 | Bui The Duy | Systems and methods for delivering cross-linked halyuronic acid into a patient |
| WO2014152488A2 (en) | 2013-03-15 | 2014-09-25 | Dreher Matthew R | Imageable embolic microsphere |
| WO2014145397A1 (en) * | 2013-03-15 | 2014-09-18 | Herskovic Arnold M | Device and method for delivering medicaments |
| CA2913100C (en) * | 2013-05-24 | 2021-10-26 | Danmarks Tekniske Universitet | Gel formulations for guiding radiotherapy |
| WO2014202738A1 (en) * | 2013-06-20 | 2014-12-24 | Nanobiotix | Compositions and methods for use in oncology |
| AU2014283217A1 (en) * | 2013-06-20 | 2015-12-24 | Nanobiotix | Compositions and methods for use in medical diagnosis |
| US10842969B2 (en) | 2013-10-25 | 2020-11-24 | Mercator Medsystems, Inc. | Systems and methods of treating malacia by local delivery of hydrogel to augment tissue |
| US12144519B2 (en) * | 2014-04-03 | 2024-11-19 | Corbin Clinical Resources, Llc | Transperineal prostate biopsy and treatment methods |
| US10743909B2 (en) | 2014-04-03 | 2020-08-18 | Corbin Clinical Resources, Llc | Transperineal prostate biopsy device, systems, and methods of use |
| US9561095B1 (en) * | 2015-10-12 | 2017-02-07 | Phi Nguyen | Body augmentation device |
| US10022475B2 (en) * | 2014-05-01 | 2018-07-17 | Bao Tran | Body augmentation device |
| US9636210B2 (en) | 2014-05-19 | 2017-05-02 | Mentor Worldwide Llc | Injection zone markers for biomedical implants |
| US9678022B2 (en) * | 2014-09-05 | 2017-06-13 | The Boeing Company | Nonaqueous radiopaque fluid and associated imaging system and method |
| KR101555358B1 (ko) * | 2014-10-21 | 2015-09-24 | 사회복지법인 삼성생명공익재단 | 생분해성 다중블록 공중합체를 이용한 표적 표지자 |
| US10550187B2 (en) | 2014-10-24 | 2020-02-04 | Incept, Llc | Extra luminal scaffold |
| AU2015360469B2 (en) | 2014-12-10 | 2021-03-25 | Incept, Llc | Hydrogel drug delivery implants |
| MX2017007873A (es) | 2014-12-15 | 2017-11-06 | Univ Johns Hopkins | Formulaciones de sunitinib y metodos para uso de las mismas en el tratamiento de trastornos oculares. |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| EP3288626B8 (en) | 2015-04-27 | 2025-12-10 | Tulavi Therapeutics, Inc. | Substances and compositions for use in blocking nerve regeneration |
| WO2016183296A1 (en) | 2015-05-12 | 2016-11-17 | Incept, Llc | Drug delivery from hydrogels |
| JP2018516256A (ja) | 2015-05-28 | 2018-06-21 | ナノビオティックスNanobiotix | 治療用ワクチンとしての使用のためのナノ粒子 |
| US20170103184A1 (en) * | 2015-10-12 | 2017-04-13 | Phi Nguyen | Injectable filler |
| US10441548B2 (en) | 2015-11-12 | 2019-10-15 | Graybug Vision, Inc. | Aggregating microparticles for medical therapy |
| US20170136144A1 (en) | 2015-11-12 | 2017-05-18 | John C. Herr | Compositions and methods for vas-occlusive contraception |
| AU2016361579B2 (en) | 2015-11-25 | 2022-08-04 | Incept, Llc | Shape changing drug delivery devices and methods |
| WO2017139487A1 (en) | 2016-02-09 | 2017-08-17 | Northwind Medical, Inc. | Methods, agents, and devices for local neuromodulation of autonomic nerves |
| AU2017290353B2 (en) | 2016-06-29 | 2023-05-18 | Tulavi Therapeutics, Inc. | Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system |
| US12702639B2 (en) * | 2016-07-07 | 2026-08-11 | University Of Virginia Patent Foundation | Thiol-michael addition hydrogel-based brachytherapy system and methods comprising the same |
| CA3029806A1 (en) * | 2016-07-07 | 2018-01-11 | University Of Virginia Patent Foundation | Thiol-michael addition hydrogel-based brachytherapy system and methods comprising the same |
| CN106334213B (zh) * | 2016-08-31 | 2019-07-26 | 安疗生命科学(武汉)有限公司 | 一种血管栓塞材料、其制备方法及在药物制备中的用途 |
| KR102814241B1 (ko) | 2016-09-23 | 2025-05-29 | 인셉트, 엘엘씨 | 전안방내 약물 전달 데포 |
| ES2905695T3 (es) * | 2016-11-23 | 2022-04-11 | Hologic Inc | Marcador de sitio de biopsia |
| EP3565484B1 (en) | 2017-01-05 | 2024-04-03 | Contraline, Inc. | Compositions for implanting and reversing stimuli-responsive implants |
| US12383421B2 (en) | 2017-01-05 | 2025-08-12 | Contraline, Inc. | Contraceptive devices |
| US20180289467A1 (en) * | 2017-04-05 | 2018-10-11 | Ernesto Andrade | Dispensing device, kit, and method for tissue augmentation |
| MX2019013363A (es) | 2017-05-10 | 2020-01-13 | Graybug Vision Inc | Microparticulas de liberacion extendida y suspensiones de las mismas para terapia medica. |
| CN107307922A (zh) * | 2017-07-06 | 2017-11-03 | 刘志光 | 一种人体植入填充颗粒的制作方法 |
| WO2019010007A1 (en) * | 2017-07-07 | 2019-01-10 | Hindsite, Llc | SYSTEM AND METHOD FOR MARKING AND FOLLOWING LOCATION OF BIOPSY SITES USING RFID TECHNOLOGY |
| KR102673196B1 (ko) | 2017-09-05 | 2024-06-10 | 삼성전자주식회사 | 유기금속 화합물, 이를 포함한 유기 발광 소자 및 이를 포함한 진단용 조성물 |
| EP3691618A1 (en) | 2017-10-06 | 2020-08-12 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| US10426424B2 (en) | 2017-11-21 | 2019-10-01 | General Electric Company | System and method for generating and performing imaging protocol simulations |
| CN116650732A (zh) | 2018-01-08 | 2023-08-29 | 铸造疗法股份有限公司 | 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法 |
| JP2021517165A (ja) | 2018-03-07 | 2021-07-15 | マージン−クリア ピーティーワイ リミテッド | 局所小線源療法装置及び悪性がん細胞の治療の方法 |
| US12458589B2 (en) | 2018-05-12 | 2025-11-04 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| US11730865B2 (en) | 2018-05-15 | 2023-08-22 | Incept, Llc | Embolic compositions and methods |
| AU2019299519B2 (en) | 2018-07-02 | 2025-03-06 | Incept Llc | Methods and devices for in situ formed nerve cap |
| US20210315587A1 (en) | 2018-07-02 | 2021-10-14 | Tulavi Therapeutics, Inc. | Methods and devices for in situ formed nerve cap with rapid release |
| EP3843710A1 (en) | 2018-08-28 | 2021-07-07 | Foundry Therapeutics, Inc. | Polymer implants |
| CA3112634A1 (en) | 2018-09-13 | 2020-03-19 | Allergan, Inc. | Tissue expansion device |
| USD896383S1 (en) | 2018-09-13 | 2020-09-15 | Allergan, Inc. | Tissue expansion device |
| AU2019380413B2 (en) | 2018-11-13 | 2025-04-17 | Contraline, Inc. | Systems and methods for delivering biomaterials |
| AU2020269368B2 (en) * | 2019-05-03 | 2025-07-10 | Palette Life Sciences, Inc. | Improved tissue spacers |
| ES2963356T3 (es) * | 2019-06-12 | 2024-03-26 | Nouryon Chemicals Int Bv | Método para aislar ácido carboxílico a partir de una corriente lateral acuosa |
| US11976035B2 (en) | 2019-06-12 | 2024-05-07 | Nouryon Chemicals International B.V. | Process for the production of diacyl peroxides |
| JP7335362B2 (ja) | 2019-06-12 | 2023-08-29 | ヌーリオン ケミカルズ インターナショナル ベスローテン フェノーツハップ | 過酸化ジアシルを生成するためのプロセス |
| JP7281564B2 (ja) | 2019-06-12 | 2023-05-25 | ヌーリオン ケミカルズ インターナショナル ベスローテン フェノーツハップ | 過酸化ジアシルを生成するためのプロセス |
| JP7281563B2 (ja) | 2019-06-12 | 2023-05-25 | ヌーリオン ケミカルズ インターナショナル ベスローテン フェノーツハップ | ペルオキシエステルを生成するためのプロセス |
| CN114269393A (zh) | 2019-08-28 | 2022-04-01 | 波士顿科学医学有限公司 | 具有支化端基的反应性多臂聚合物 |
| AU2020337329B2 (en) | 2019-08-28 | 2024-07-11 | Boston Scientific Scimed, Inc. | Radiopaque multi-armed polymers and compositions, systems and methods pertaining to the same |
| WO2021041222A1 (en) | 2019-08-28 | 2021-03-04 | Boston Scientific Scimed, Inc. | Multi-armed polyoxazolines and compositions, systems and methods pertaining to the same |
| US11326022B2 (en) | 2019-08-28 | 2022-05-10 | Boston Scientific Scimed, Inc. | Multi-armed polymers comprising free-radical-polymerizable monomers and compositions, systems and methods pertaining to the same |
| US11878092B2 (en) | 2019-08-28 | 2024-01-23 | Boston Scientific Scimed, Inc. | Medical compositions based on crosslinkable hydrophilic polymers |
| US11820868B2 (en) | 2019-08-28 | 2023-11-21 | Boston Scientific Scimed, Inc. | Multifunctional nitroxide-mediated polymerization initiators and multi-armed polymers and hydrogels formed therefrom |
| AU2021206966A1 (en) * | 2020-01-14 | 2022-08-04 | Mochida Pharmaceutical Co., Ltd. | Combination and method for treating subject using alginic acid salt |
| CN115052641A (zh) | 2020-02-04 | 2022-09-13 | 波士顿科学国际有限公司 | 用作软组织填充物的可注射体内交联材料 |
| WO2021207181A1 (en) * | 2020-04-06 | 2021-10-14 | Corbin Clinical Resources, Llc | Transperineal prostate biopsy and treatment methods |
| CN111905155B (zh) * | 2020-07-23 | 2021-10-15 | 北京诺康达医药科技股份有限公司 | 一种封闭水凝胶及其制备方法和应用 |
| US12343454B2 (en) | 2020-11-12 | 2025-07-01 | Pramand LLC | Hydrogels formed in situ and composition design for intrauterine use |
| US20220142653A1 (en) | 2020-11-12 | 2022-05-12 | Pramand LLC | Transcervical access systems for intrauterine fluid exchange, such as placement of hydrogels formed in situ |
| EP4312983A4 (en) * | 2021-03-30 | 2025-01-22 | Tulavi Therapeutics, Inc. | METHODS AND COMPOSITIONS FOR ABLATION OF NERVES |
| EP4422596A1 (en) | 2021-10-25 | 2024-09-04 | Boston Scientific Scimed Inc. | Iodine labeled hydrogels and precursors thereof with improved radiopacity |
| EP4464339A4 (en) * | 2022-01-13 | 2026-08-05 | Nat Cancer Ct | BIOCOMPATIBLE COMPOSITION FOR MARKING A TARGET LESION, AND ITS PREPARATION PROCESS |
| JP7744528B2 (ja) | 2022-02-02 | 2025-09-25 | ボストン サイエンティフィック サイムド,インコーポレイテッド | ヨウ素化化合物及びこれから形成されるヒドロゲル |
| CN114344554A (zh) * | 2022-02-11 | 2022-04-15 | 上海益思妙医疗器械有限公司 | 一种peg化合物作为制备栓塞剂的应用 |
| US11701451B1 (en) | 2022-03-11 | 2023-07-18 | Carbon Medical Technologies, Inc. | Soft tissue filler and methods |
| US12251466B2 (en) | 2022-04-20 | 2025-03-18 | Pramand LLC | Single solution hydrogels with covalent bonding formed in situ, composition design and medical procedures using the hydrogels |
| US12440599B2 (en) | 2022-05-06 | 2025-10-14 | Pramand LLC | Water activated hydrogel-based medical patches, and methods of making and using such patches |
| US20250360172A1 (en) * | 2022-05-25 | 2025-11-27 | Cedars-Sinai Medical Center | Microgel-encapsulated ipsc-derived notochordal cells for treatment of intervertebral disc degeneration and discogenic pain |
| CN119731240A (zh) | 2022-08-17 | 2025-03-28 | 波士顿科学医学有限公司 | 具有改进性能的碘标记水凝胶及其前体 |
| EP4623020A1 (en) | 2022-11-21 | 2025-10-01 | Boston Scientific Scimed Inc. | Iodine labeled hydrogels and crosslinking agents for forming the same |
| US20240181139A1 (en) * | 2022-12-06 | 2024-06-06 | Pramand LLC | Chemical tissue ablation with hydrogel matrix and corresponding medical applications |
| US20240301179A1 (en) | 2023-03-02 | 2024-09-12 | Boston Scientific Scimed, Inc. | Polyamino iodinated compounds and radiopaque hydrogels formed therefrom |
| WO2024182523A1 (en) | 2023-03-02 | 2024-09-06 | Boston Scientific Scimed, Inc. | Therapeutic-agent-releasing hydrogels and precursors thereof |
| DE102023108039A1 (de) | 2023-03-29 | 2024-10-02 | Dwi - Leibniz-Institut Für Interaktive Materialien E.V. | Ein System zur Herstellung eines degradierbaren Hydrogels |
| WO2024227165A1 (en) * | 2023-04-28 | 2024-10-31 | Boston Scientific Scimed, Inc. | Suspensions of radiopaque crosslinked hydrogel particles in carrier fluids containing biocompatible hydrophilic polymers |
| WO2025059725A1 (en) | 2023-09-20 | 2025-03-27 | Margin-Clear Pty Ltd | Improved brachytherapy device |
| CN122122219A (zh) | 2023-11-01 | 2026-05-29 | 波士顿科学医学有限公司 | 基于氨基酸和氨基醇的多胺化合物以及由其形成的医用水凝胶 |
| US20250228774A1 (en) * | 2024-01-11 | 2025-07-17 | Boston Scientific Scimed, Inc. | Systems and methods for accelerated hydrolysis of polysaccharide-based hydrogels |
Family Cites Families (156)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3640741A (en) | 1970-02-24 | 1972-02-08 | Hollister Inc | Composition containing gel |
| US3865108A (en) | 1971-05-17 | 1975-02-11 | Ortho Pharma Corp | Expandable drug delivery device |
| US3872856A (en) | 1971-06-09 | 1975-03-25 | Ralph S Clayton | Apparatus for treating the walls and floor of the pelvic cavity with radiation |
| US4002173A (en) | 1974-07-23 | 1977-01-11 | International Paper Company | Diester crosslinked polyglucan hydrogels and reticulated sponges thereof |
| DE2437629C3 (de) | 1974-08-05 | 1978-09-21 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von unlöslichen in Wasser nur wenig quellbaren Polymerisaten von N-Vinyllactamen |
| US4014335A (en) | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
| US4193813A (en) | 1976-09-07 | 1980-03-18 | Medi-Coll, Inc. | Method for making collagen sponge |
| US4207893A (en) | 1977-08-29 | 1980-06-17 | Alza Corporation | Device using hydrophilic polymer for delivering drug to biological environment |
| IL74715A0 (en) | 1984-03-27 | 1985-06-30 | Univ New Jersey Med | Biodegradable matrix and methods for producing same |
| US4697575A (en) | 1984-11-21 | 1987-10-06 | Henry Ford Hospital | Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member |
| US4674488A (en) | 1985-03-04 | 1987-06-23 | American Hospital Supply Corporation | Method of treating bone fractures to reduce formation of fibrous adhesions |
| US4714074A (en) | 1985-06-28 | 1987-12-22 | Centre National De La Recherche Scientifique | Method for protecting human or animal organs against radiation |
| US4706652A (en) | 1985-12-30 | 1987-11-17 | Henry Ford Hospital | Temporary radiation therapy |
| US5160745A (en) | 1986-05-16 | 1992-11-03 | The University Of Kentucky Research Foundation | Biodegradable microspheres as a carrier for macromolecules |
| US4741872A (en) | 1986-05-16 | 1988-05-03 | The University Of Kentucky Research Foundation | Preparation of biodegradable microspheres useful as carriers for macromolecules |
| IL82834A (en) | 1987-06-09 | 1990-11-05 | Yissum Res Dev Co | Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US5304595A (en) | 1988-11-21 | 1994-04-19 | Collagen Corporation | Collagen-polymer conjugates |
| US5550187A (en) | 1988-11-21 | 1996-08-27 | Collagen Corporation | Method of preparing crosslinked biomaterial compositions for use in tissue augmentation |
| US5306500A (en) | 1988-11-21 | 1994-04-26 | Collagen Corporation | Method of augmenting tissue with collagen-polymer conjugates |
| US5162430A (en) | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
| IL90193A (en) | 1989-05-04 | 1993-02-21 | Biomedical Polymers Int | Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same |
| US5324519A (en) | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US5529914A (en) | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
| US5410016A (en) | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
| CA2094908C (en) | 1990-12-06 | 2000-02-08 | Byron Kent Hayes | Implantable bioabsorbable article |
| FR2672713A1 (fr) * | 1991-02-13 | 1992-08-14 | Inst Nat Polytech Grenoble | Composant d'alimentation du type carte de credit. |
| US6537574B1 (en) | 1992-02-11 | 2003-03-25 | Bioform, Inc. | Soft tissue augmentation material |
| US5629008A (en) | 1992-06-02 | 1997-05-13 | C.R. Bard, Inc. | Method and device for long-term delivery of drugs |
| US5514379A (en) | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
| US6592859B1 (en) | 1992-08-20 | 2003-07-15 | Ethicon, Inc. | Controlled expansion sphincter augmentation media |
| DE69331387T2 (de) | 1992-09-10 | 2002-08-22 | Childrens Medical Center | Biodegradierbare polymeren matrizen mit verzoegerter freisetzung von lokalanaesthetika |
| DE69412474T2 (de) | 1993-04-28 | 1998-12-17 | Focal, Inc., Lexington, Mass. | Vorrichtung, produkt und verwendung betreffend die intraluminale photothermoformgebung |
| US5709854A (en) | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US5565215A (en) * | 1993-07-23 | 1996-10-15 | Massachusettes Institute Of Technology | Biodegradable injectable particles for imaging |
| US5499994A (en) | 1993-07-30 | 1996-03-19 | American Medical Systems, Inc. | Dilation device for the urethra |
| CA2188464C (en) | 1994-04-27 | 2006-08-08 | Michael Roreger | Collagen preparation for the controlled release of active substances |
| DE4414755C2 (de) | 1994-04-27 | 2000-11-16 | Lohmann Therapie Syst Lts | Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung |
| BR9607977A (pt) | 1995-03-23 | 1998-01-13 | Univ Texas | Sistemas de preparação fotoiniciados e redox para a obtenção de aderência melhorada de géis a substratos |
| US5900245A (en) | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
| US6214331B1 (en) | 1995-06-06 | 2001-04-10 | C. R. Bard, Inc. | Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained |
| US6129761A (en) | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
| AU6403196A (en) | 1995-06-30 | 1997-02-05 | Baylor University | Polyester/carboxylic acid composite materials |
| US5827937A (en) | 1995-07-17 | 1998-10-27 | Q Med Ab | Polysaccharide gel composition |
| WO1997005185A2 (en) | 1995-07-28 | 1997-02-13 | Focal, Inc. | Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatment agents |
| RU2177332C2 (ru) | 1995-08-29 | 2001-12-27 | Фидиа Адвансд Биополимерз, С.Р.Л. | Биоматериал для предотвращения послеоперационных спаек, включающий производные гиалуроновой кислоты (варианты) и способ предотвращения послеоперационных спаек ткани |
| US5759583A (en) | 1995-08-30 | 1998-06-02 | Syntex (U.S.A.) Inc. | Sustained release poly (lactic/glycolic) matrices |
| US5733316A (en) | 1995-10-27 | 1998-03-31 | Dornier Medical Systems, Inc. | Organ separation for thermal therapy |
| US5863984A (en) | 1995-12-01 | 1999-01-26 | Universite Laval, Cite Universitaire | Biostable porous material comprising composite biopolymers |
| WO1997022371A1 (en) | 1995-12-18 | 1997-06-26 | Collagen Corporation | Crosslinked polymer compositions and methods for their use |
| US5752974A (en) | 1995-12-18 | 1998-05-19 | Collagen Corporation | Injectable or implantable biomaterials for filling or blocking lumens and voids of the body |
| US6060534A (en) * | 1996-07-11 | 2000-05-09 | Scimed Life Systems, Inc. | Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties |
| US7049346B1 (en) | 1996-08-20 | 2006-05-23 | Menlo Care Div Of Ethicon, Inc. | Swollen hydrogel for sphincter augmentation |
| US6063061A (en) | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
| US20020064546A1 (en) * | 1996-09-13 | 2002-05-30 | J. Milton Harris | Degradable poly(ethylene glycol) hydrogels with controlled half-life and precursors therefor |
| ZA978537B (en) | 1996-09-23 | 1998-05-12 | Focal Inc | Polymerizable biodegradable polymers including carbonate or dioxanone linkages. |
| WO1998012274A1 (en) | 1996-09-23 | 1998-03-26 | Chandrashekar Pathak | Methods and devices for preparing protein concentrates |
| US7009034B2 (en) | 1996-09-23 | 2006-03-07 | Incept, Llc | Biocompatible crosslinked polymers |
| US6214966B1 (en) | 1996-09-26 | 2001-04-10 | Shearwater Corporation | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution |
| US5932539A (en) | 1996-10-15 | 1999-08-03 | The Board Of Trustees Of The University Of Illinois | Biodegradable polymer matrix for tissue repair |
| JP3092530B2 (ja) | 1996-11-05 | 2000-09-25 | 日本油脂株式会社 | コハク酸イミジル基置換ポリオキシアルキレン誘導体の製造方法 |
| JP3092531B2 (ja) | 1996-11-05 | 2000-09-25 | 日本油脂株式会社 | コハク酸イミジル基置換ポリオキシアルキレン誘導体の製造方法 |
| US6371975B2 (en) | 1998-11-06 | 2002-04-16 | Neomend, Inc. | Compositions, systems, and methods for creating in situ, chemically cross-linked, mechanical barriers |
| US6224893B1 (en) | 1997-04-11 | 2001-05-01 | Massachusetts Institute Of Technology | Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering |
| US6271278B1 (en) | 1997-05-13 | 2001-08-07 | Purdue Research Foundation | Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties |
| IL121861A (en) | 1997-09-29 | 2003-07-31 | Moshe Ein Gal | Prostate radiotherapy apparatus |
| JP2001519203A (ja) | 1997-10-10 | 2001-10-23 | ジョン・ディ・コービット・ジュニア | 胸部インプラント |
| US8288745B2 (en) | 1997-10-10 | 2012-10-16 | Senorx, Inc. | Method of utilizing an implant for targeting external beam radiation |
| IL135800A0 (en) | 1997-10-27 | 2001-05-20 | Univ California | Methods and pharmaceutical compositions for the closure of retinal breaks |
| JP4465105B2 (ja) * | 1997-11-07 | 2010-05-19 | ルトガーズ、ザ ステイト ユニバーシティ オブ ニュージャージー | 放射線不透過性ポリマー生体適合材料 |
| US6375634B1 (en) | 1997-11-19 | 2002-04-23 | Oncology Innovations, Inc. | Apparatus and method to encapsulate, kill and remove malignancies, including selectively increasing absorption of x-rays and increasing free-radical damage to residual tumors targeted by ionizing and non-ionizing radiation therapy |
| US6660301B1 (en) | 1998-03-06 | 2003-12-09 | Biosphere Medical, Inc. | Injectable microspheres for dermal augmentation and tissue bulking |
| US6428978B1 (en) | 1998-05-08 | 2002-08-06 | Cohesion Technologies, Inc. | Methods for the production of gelatin and full-length triple helical collagen in recombinant cells |
| US6066856A (en) | 1998-05-18 | 2000-05-23 | Children's Medical Center Corporation | Radiation protective device |
| US6280742B1 (en) * | 1998-06-17 | 2001-08-28 | Zonagen, Inc. | Methods and materials for the treatment of prostatic carcinoma |
| US6206930B1 (en) | 1998-08-10 | 2001-03-27 | Charlotte-Mecklenburg Hospital Authority | Absorbable tissue expander |
| US6632457B1 (en) | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
| ATE502670T1 (de) | 1998-08-14 | 2011-04-15 | Incept Llc | Apparat für die in-situ-bildung von hydrogelen |
| US6152943A (en) | 1998-08-14 | 2000-11-28 | Incept Llc | Methods and apparatus for intraluminal deposition of hydrogels |
| US6605294B2 (en) | 1998-08-14 | 2003-08-12 | Incept Llc | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels |
| US6703047B2 (en) | 2001-02-02 | 2004-03-09 | Incept Llc | Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use |
| US6514534B1 (en) | 1998-08-14 | 2003-02-04 | Incept Llc | Methods for forming regional tissue adherent barriers and drug delivery systems |
| US6818018B1 (en) | 1998-08-14 | 2004-11-16 | Incept Llc | In situ polymerizable hydrogels |
| US6179862B1 (en) | 1998-08-14 | 2001-01-30 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
| ES2219070T3 (es) | 1998-10-22 | 2004-11-16 | Bioniche Life Sciences Inc. | Uso de acido haluronico en el tratamiento de la cistitis por radiacion. |
| US8802146B2 (en) * | 1998-11-06 | 2014-08-12 | Neomend, Inc. | Systems, methods, and compositions for prevention of tissue adhesion |
| US6899889B1 (en) | 1998-11-06 | 2005-05-31 | Neomend, Inc. | Biocompatible material composition adaptable to diverse therapeutic indications |
| JP4551563B2 (ja) | 1998-11-10 | 2010-09-29 | 電気化学工業株式会社 | ヒアルロン酸ゲルの製造方法及び医用材料 |
| WO2000028919A1 (en) | 1998-11-12 | 2000-05-25 | Canadian Prostate Centre, Inc. | Apparatus and method of separating organs to enable aggressive thermal therapy |
| US6110484A (en) | 1998-11-24 | 2000-08-29 | Cohesion Technologies, Inc. | Collagen-polymer matrices with differential biodegradability |
| EP1137373A4 (en) | 1998-12-04 | 2004-05-19 | Chandrashekhar P Pathak | BIOCOMPATIBLE, CROSSLINKED POLYMERS |
| US20080114092A1 (en) | 1998-12-04 | 2008-05-15 | Incept Llc | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof |
| TW392930U (en) * | 1998-12-28 | 2000-06-01 | Hon Hai Prec Ind Co Ltd | Electric connector |
| US6958212B1 (en) | 1999-02-01 | 2005-10-25 | Eidgenossische Technische Hochschule Zurich | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds |
| US6862470B2 (en) | 1999-02-02 | 2005-03-01 | Senorx, Inc. | Cavity-filling biopsy site markers |
| AU780397B2 (en) | 1999-02-03 | 2005-03-17 | Powderject Research Limited | Hydrogel particle formulations |
| US6177514B1 (en) | 1999-04-09 | 2001-01-23 | Sulzer Carbomedics Inc. | Blocked functional reagants for cross-linking biological tissues |
| ES2298135T3 (es) | 1999-04-12 | 2008-05-16 | Cornell Research Foundation, Inc. | Sistema formador de hidrogel con componentes hidrofobos e hidrofilos. |
| US6312725B1 (en) | 1999-04-16 | 2001-11-06 | Cohesion Technologies, Inc. | Rapid gelling biocompatible polymer composition |
| US6268405B1 (en) | 1999-05-04 | 2001-07-31 | Porex Surgical, Inc. | Hydrogels and methods of making and using same |
| US6426145B1 (en) | 1999-05-20 | 2002-07-30 | Scimed Life Systems, Inc. | Radiopaque compositions for visualization of medical devices |
| US6428785B1 (en) | 1999-10-28 | 2002-08-06 | Immunolytics Inc. | Method and composition for treating prostate cancer |
| US6509031B1 (en) | 1999-11-15 | 2003-01-21 | Board Of Regents, Texas A&M University System | System for polymerizing collagen and collagen composites in situ for a tissue compatible wound sealant, delivery vehicle, binding agent and/or chemically modifiable matrix |
| US6479079B1 (en) | 1999-12-13 | 2002-11-12 | Sulzer Carbomedics Inc. | Anticalcification treatments for fixed biomaterials |
| JP2001192336A (ja) | 2000-01-11 | 2001-07-17 | Hironori Yamamoto | 高粘性物質を用いた内視鏡的粘膜切除術 |
| US6436424B1 (en) | 2000-03-20 | 2002-08-20 | Biosphere Medical, Inc. | Injectable and swellable microspheres for dermal augmentation |
| US9314339B2 (en) | 2000-03-27 | 2016-04-19 | Formae, Inc. | Implants for replacing cartilage, with negatively-charged hydrogel surfaces and flexible matrix reinforcement |
| EP1142535B1 (en) | 2000-04-07 | 2012-10-03 | Collagen Matrix, Inc. | Embolization device |
| US6599448B1 (en) * | 2000-05-10 | 2003-07-29 | Hydromer, Inc. | Radio-opaque polymeric compositions |
| US6383344B1 (en) | 2000-07-19 | 2002-05-07 | Genzyme Corporation | Molecular weight reduction of polymer using irradiation treatment |
| US6545097B2 (en) | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
| US6596471B2 (en) | 2000-12-21 | 2003-07-22 | Carbomedics Inc. | Method of cross-linking tissue with a bis-maleimide compound |
| CA2438193A1 (en) | 2001-02-26 | 2002-09-06 | Duke University | Novel dendritic polymers and their biomedical uses |
| JP4123856B2 (ja) | 2001-07-31 | 2008-07-23 | 日油株式会社 | 生体関連物質の修飾剤およびポリオキシアルキレン誘導体の製造方法 |
| CN1277805C (zh) | 2001-10-03 | 2006-10-04 | 大日本除虫菊株式会社 | 炔丙基苄基醇酯衍生物、其制备方法和含有其的杀虫·防虫剂 |
| US7008626B2 (en) | 2001-11-05 | 2006-03-07 | Seikagaku Corporation | Medical composition for protuberance of epithelium |
| US20070264227A1 (en) | 2001-11-07 | 2007-11-15 | Eidgenossische Technische Hochschule Zurich | Synthetic Matrix for Controlled Cell Ingrowth and Tissue Regeneration |
| US20040131582A1 (en) | 2002-02-26 | 2004-07-08 | Grinstaff Mark W. | Novel dendritic polymers and their biomedical uses |
| US7341716B2 (en) * | 2002-04-12 | 2008-03-11 | Boston Scientific Scimed, Inc. | Occlusive composition |
| WO2004000103A2 (en) | 2002-06-24 | 2003-12-31 | Noyes William R | Fillers and methods for displacing tissues to improve radiological outcomes |
| US7351430B2 (en) | 2002-11-06 | 2008-04-01 | Uluru Inc. | Shape-retentive hydrogel particle aggregates and their uses |
| US7129210B2 (en) | 2003-07-23 | 2006-10-31 | Covalent Medical, Inc. | Tissue adhesive sealant |
| US20050033157A1 (en) * | 2003-07-25 | 2005-02-10 | Klein Dean A. | Multi-modality marking material and method |
| US7790141B2 (en) * | 2003-08-11 | 2010-09-07 | Pathak Holdings, Llc | Radio-opaque compounds, compositions containing same and methods of their synthesis and use |
| RU2373958C2 (ru) | 2003-09-25 | 2009-11-27 | Рутгерс, Дзе Стейт Юниверсити | Полимерные по существу рентгеноконтрастные продукты для эмболотерапии |
| US20050226936A1 (en) | 2004-04-08 | 2005-10-13 | Q-Med Ab | Method of soft tissue augmentation |
| CA2571304A1 (en) | 2004-06-23 | 2006-01-05 | Bioprotect Ltd. | Device system and method for tissue displacement or separation |
| FR2872262B1 (fr) | 2004-06-29 | 2010-11-26 | Air Liquide | Procede et installation de fourniture de secours d'un gaz sous pression |
| WO2006031358A2 (en) | 2004-08-13 | 2006-03-23 | Hyperbranch Medical Technology, Inc. | Dendritic polymers, crosslinked gels, and their uses as ophthalmic sealants and lenses |
| RU2396289C2 (ru) | 2004-08-13 | 2010-08-10 | Рева Медикал, Инк. | Саморассасывающиеся рентгеноконтрастные по своей природе полимеры для многоцелевого использования |
| WO2006031388A2 (en) | 2004-08-20 | 2006-03-23 | Hyperbranch Medical Technology, Inc. | Dentritic polymers, crosslinked gels, and their uses in orthopedic applications |
| WO2006026325A2 (en) | 2004-08-26 | 2006-03-09 | Pathak Chandrashekhar P | Implantable tissue compositions and method |
| WO2006078770A2 (en) | 2005-01-21 | 2006-07-27 | Civco Medical Instruments Co., Inc. | Creating temporary space between body tissues |
| US7963287B2 (en) * | 2005-04-28 | 2011-06-21 | Boston Scientific Scimed, Inc. | Tissue-treatment methods |
| WO2007001926A2 (en) | 2005-06-24 | 2007-01-04 | Hyperbranch Medical Technology, Inc. | Low-swelling hydrogel sealants for wound repair |
| WO2007005249A2 (en) | 2005-06-29 | 2007-01-11 | Hyperbranch Medical Technology, Inc. | Nanoparticles and dendritic-polymer-based hydrogels comprising them |
| DE102005051366A1 (de) * | 2005-10-25 | 2007-04-26 | Degussa Gmbh | Drug Delivery Systeme |
| EP1996243B1 (en) | 2006-01-11 | 2014-04-23 | HyperBranch Medical Technology, Inc. | Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices |
| US8795709B2 (en) | 2006-03-29 | 2014-08-05 | Incept Llc | Superabsorbent, freeze dried hydrogels for medical applications |
| US7597882B2 (en) | 2006-04-24 | 2009-10-06 | Incept Llc | Protein crosslinkers, crosslinking methods and applications thereof |
| US7872068B2 (en) | 2006-05-30 | 2011-01-18 | Incept Llc | Materials formable in situ within a medical device |
| WO2008097581A1 (en) | 2007-02-06 | 2008-08-14 | Incept, Llc | Polymerization with precipitation of proteins for elution in physiological solution |
| WO2008101173A2 (en) | 2007-02-16 | 2008-08-21 | Cornell University | Biodegradable compositions and materials |
| US20080220047A1 (en) | 2007-03-05 | 2008-09-11 | Sawhney Amarpreet S | Low-swelling biocompatible hydrogels |
| US9987221B2 (en) | 2007-08-23 | 2018-06-05 | Boston Scientific Scimed, Inc. | Injectable hydrogel compositions |
| CA2707649A1 (en) | 2007-11-02 | 2009-05-07 | Genzyme Corporation | Methods of augmenting or repairing soft tissue |
| EP2247645B1 (en) | 2008-02-13 | 2017-12-06 | Hyperbranch Medical Technology, Inc. | Crosslinked polyalkyleneimine hydrogels with tunable degradation rates |
| JP5788326B2 (ja) | 2008-11-03 | 2015-09-30 | コーネル ユニバーシティー | ジヒドロキシアセトンのポリマー組成物およびその使用 |
| CN101724144A (zh) | 2008-11-03 | 2010-06-09 | 北京键凯科技有限公司 | 新型的多臂聚乙二醇及其制备方法和应用 |
| EP3960215B1 (en) * | 2009-12-15 | 2024-10-16 | Incept, LLC | Implants and biodegradable fiducial markers |
| US8734930B2 (en) | 2010-05-27 | 2014-05-27 | Covidien Lp | Hydrogel implants with varying degrees of crosslinking |
| US9789231B2 (en) | 2013-02-08 | 2017-10-17 | Endoshape, Inc. | Radiopaque polymers for medical devices |
| US9789073B2 (en) | 2013-03-14 | 2017-10-17 | Pathak Holdings, Llc | Compositions, methods and devices for local drug delivery |
| CN104448296B (zh) | 2013-12-02 | 2018-01-05 | 北京键凯科技股份有限公司 | 炔基多臂聚乙二醇衍生物 |
| CN106146325B (zh) | 2015-04-24 | 2019-01-29 | 北京键凯科技股份有限公司 | 一种y型多缩乙二醇衍生物及其制备方法 |
| EP3681934A1 (en) * | 2017-09-15 | 2020-07-22 | Université de Strasbourg | Injectable hybrid alginate hydrogels and uses thereof |
-
2010
- 2010-12-15 EP EP21203718.8A patent/EP3960215B1/en active Active
- 2010-12-15 CA CA3042067A patent/CA3042067C/en active Active
- 2010-12-15 CA CA3149284A patent/CA3149284C/en active Active
- 2010-12-15 JP JP2012544750A patent/JP5820815B2/ja active Active
- 2010-12-15 WO PCT/US2010/060474 patent/WO2011084465A2/en not_active Ceased
- 2010-12-15 AU AU2010340067A patent/AU2010340067B2/en active Active
- 2010-12-15 CN CN201080063960.2A patent/CN102844054B/zh active Active
- 2010-12-15 EP EP10842525.7A patent/EP2512540B1/en active Active
- 2010-12-15 US US12/968,527 patent/US8383161B2/en active Active
- 2010-12-15 IN IN5177DEN2012 patent/IN2012DN05177A/en unknown
- 2010-12-15 CA CA2782899A patent/CA2782899C/en active Active
- 2010-12-15 EP EP19185126.0A patent/EP3583960A1/en active Pending
-
2013
- 2013-01-25 US US13/750,570 patent/US8852646B2/en active Active
-
2014
- 2014-08-21 US US14/465,202 patent/US9308283B2/en active Active
-
2016
- 2016-03-10 US US15/066,707 patent/US9669117B2/en active Active
-
2017
- 2017-06-05 US US15/613,555 patent/US10272164B2/en active Active
-
2019
- 2019-03-08 US US16/296,795 patent/US10786581B2/en active Active
-
2020
- 2020-03-12 US US16/817,307 patent/US11154624B2/en active Active
- 2020-03-12 US US16/817,291 patent/US11083802B2/en active Active
- 2020-03-12 US US16/817,297 patent/US11160883B2/en active Active
- 2020-08-21 US US16/999,703 patent/US11786612B2/en active Active
-
2022
- 2022-01-07 US US17/571,168 patent/US12622982B2/en active Active
-
2025
- 2025-01-17 US US19/029,785 patent/US20250161497A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12622982B2 (en) | Implants and biodegradable tissue markers | |
| US20250177295A1 (en) | Single solution hydrogels with covalent bonding formed in situ, composition design and medical procedures using the hydrogels | |
| US20240091141A1 (en) | Methods and compositions for the ablation of nerves | |
| AU2020269368A1 (en) | Improved tissue spacers | |
| KR20240155241A (ko) | 시각화 첨가제가 포함된 개선된 조직 스페이서 | |
| HK40115702A (en) | Single solution hydrogels with covalent bonding formed in situ, composition design and medical procedures using the hydrogels | |
| Forster | Hydrogel microspheres for the treatment of tumours |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20191031 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 14TH ANNIV.) - STANDARD Year of fee payment: 14 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20241206 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20241206 |