CA3040025C - Conserved hbv and hcv sequences useful for gene silencing - Google Patents
Conserved hbv and hcv sequences useful for gene silencing Download PDFInfo
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- CA3040025C CA3040025C CA3040025A CA3040025A CA3040025C CA 3040025 C CA3040025 C CA 3040025C CA 3040025 A CA3040025 A CA 3040025A CA 3040025 A CA3040025 A CA 3040025A CA 3040025 C CA3040025 C CA 3040025C
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| EP2514758B2 (en) | 2004-03-15 | 2021-06-23 | City of Hope | Methods and compositions for the specific inhibition of gene expression by double-stranded RNA |
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| ES2362670T3 (es) | 2004-09-24 | 2011-07-11 | Alnylam Pharmaceuticals, Inc | Orientación a intermedios de replicación de hebra no codificante de virus monocatenarios por arni. |
| EP2316942B1 (en) * | 2004-12-22 | 2021-04-21 | Alnylam Pharmaceuticals, Inc. | Conserved hbv and hcv sequences useful for gene silencing |
| WO2011103394A2 (en) * | 2010-02-19 | 2011-08-25 | Agave Pharma Inc. | Methods for gene inhibition |
| AU2011223820B2 (en) * | 2010-03-01 | 2016-01-14 | The Children's Hospital Of Philadelphia | Nucleic acids for targeting multiple regions of the HCV genome |
| HUE044815T2 (hu) * | 2010-08-17 | 2019-11-28 | Sirna Therapeutics Inc | Hepatitisz B vírus (HBV) génexpressziójának RNS-interferencia közvetített gátlása, rövid interferáló nukleinsav (SINS) alkalmazásával |
| UA118951C2 (uk) | 2011-04-21 | 2019-04-10 | Айоніс Фармасьютікалз, Інк. | Модулювання експресії вірусу гепатиту b (hbv) |
| TWI620568B (zh) | 2012-08-30 | 2018-04-11 | 雷普利可公司 | 用於治療ｂ型肝炎及ｄ型肝炎感染之方法 |
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| MX374530B (es) | 2013-12-12 | 2025-03-06 | Broad Inst Inc | Suministro, uso y aplicaciones terapeuticas de los sistemas y composiciones crispr-cas para actuar sobre hbv y trastornos y enfermedades virales. |
| JOP20200092A1 (ar) | 2014-11-10 | 2017-06-16 | Alnylam Pharmaceuticals Inc | تركيبات iRNA لفيروس الكبد B (HBV) وطرق لاستخدامها |
| HK1251010A1 (zh) * | 2015-05-06 | 2019-01-18 | Benitec IP Holdings Inc. | 用於治疗乙型肝炎病毒(hbv)感染的试剂及用途 |
| US20170016000A1 (en) | 2015-07-17 | 2017-01-19 | Arcturus Therapeutics, Inc. | Compositions and agents against hepatitis b virus and uses thereof |
| US20170137821A1 (en) | 2015-07-17 | 2017-05-18 | Arcturus Therapeutics, Inc. | Molecules and agents for treating hepatitis b virus |
| PT3430141T (pt) | 2016-03-14 | 2021-02-25 | Hoffmann La Roche | Oligonucleótidos para redução da expressão de pd-l1 |
| MA45496A (fr) | 2016-06-17 | 2019-04-24 | Hoffmann La Roche | Molécules d'acide nucléique pour la réduction de l'arnm de padd5 ou pad7 pour le traitement d'une infection par l'hépatite b |
| JP2019535839A (ja) | 2016-11-29 | 2019-12-12 | ピュアテック ヘルス エルエルシー | 治療剤の送達のためのエクソソーム |
| US11324820B2 (en) | 2017-04-18 | 2022-05-10 | Alnylam Pharmaceuticals, Inc. | Methods for the treatment of subjects having a hepatitis b virus (HBV) infection |
| WO2019051812A1 (zh) * | 2017-09-15 | 2019-03-21 | 深圳华大智造科技有限公司 | 确定预定染色体保守区域的方法、确定样本基因组中是否存在拷贝数变异的方法、系统和计算机可读介质 |
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| RU2020135289A (ru) | 2018-04-05 | 2022-05-05 | Ф. Хоффманн-Ля Рош Аг | Применение ингибиторов fubp1 для лечения инфекции вирусом гепатита в |
| SG11202012759XA (en) | 2018-07-03 | 2021-01-28 | Hoffmann La Roche | Oligonucleotides for modulating tau expression |
| KR20210033004A (ko) | 2018-07-13 | 2021-03-25 | 에프. 호프만-라 로슈 아게 | Rtel1의 발현을 조절하기 위한 올리고뉴클레오티드 |
| AU2019321375A1 (en) | 2018-08-13 | 2021-03-11 | Alnylam Pharmaceuticals, Inc. | Hepatitis B virus (HBV) dsRNA agent compositions and methods of use thereof |
| EP4077670A1 (en) | 2019-12-19 | 2022-10-26 | F. Hoffmann-La Roche AG | Use of cops3 inhibitors for treating hepatitis b virus infection |
| WO2021122993A1 (en) | 2019-12-19 | 2021-06-24 | F. Hoffmann-La Roche Ag | Use of saraf inhibitors for treating hepatitis b virus infection |
| WO2021122910A1 (en) | 2019-12-19 | 2021-06-24 | F. Hoffmann-La Roche Ag | Use of sbds inhibitors for treating hepatitis b virus infection |
| EP4077667A1 (en) | 2019-12-19 | 2022-10-26 | F. Hoffmann-La Roche AG | Use of sept9 inhibitors for treating hepatitis b virus infection |
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| CN116157522A (zh) | 2020-08-21 | 2023-05-23 | 豪夫迈·罗氏有限公司 | A1cf抑制剂用于治疗乙型肝炎病毒感染的用途 |
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| CN1836042A (zh) | 2006-09-20 |
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| JP2011224013A (ja) | 2011-11-10 |
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