CA3034649A1 - Methods for the detection of genomic copy changes in dna samples - Google Patents

Methods for the detection of genomic copy changes in dna samples Download PDF

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Publication number
CA3034649A1
CA3034649A1 CA3034649A CA3034649A CA3034649A1 CA 3034649 A1 CA3034649 A1 CA 3034649A1 CA 3034649 A CA3034649 A CA 3034649A CA 3034649 A CA3034649 A CA 3034649A CA 3034649 A1 CA3034649 A1 CA 3034649A1
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region
dna
sample
adaptors
genomic dna
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French (fr)
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Christopher K. Raymond
Lee P. Lim
Jennifer Hernandez
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Resolution Bioscience Inc
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Resolution Bioscience Inc
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
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    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
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    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/16—Assays for determining copy number or wherein the copy number is of special importance
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
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    • C40B40/04—Libraries containing only organic compounds
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    • C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3034649A 2016-08-25 2017-08-24 Methods for the detection of genomic copy changes in dna samples Pending CA3034649A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662379593P 2016-08-25 2016-08-25
US62/379,593 2016-08-25
US201762481538P 2017-04-04 2017-04-04
US62/481,538 2017-04-04
PCT/US2017/048434 WO2018039463A1 (en) 2016-08-25 2017-08-24 Methods for the detection of genomic copy changes in dna samples

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CA3034649A1 true CA3034649A1 (en) 2018-03-01

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CA3034649A Pending CA3034649A1 (en) 2016-08-25 2017-08-24 Methods for the detection of genomic copy changes in dna samples

Country Status (13)

Country Link
US (2) US11319594B2 (https=)
EP (2) EP3504347B1 (https=)
JP (4) JP7217224B2 (https=)
KR (2) KR102505122B1 (https=)
CN (2) CN109804080B (https=)
AU (2) AU2017315769B2 (https=)
CA (1) CA3034649A1 (https=)
ES (1) ES3053343T3 (https=)
IL (2) IL312894A (https=)
MX (2) MX2019002093A (https=)
RU (1) RU2019108294A (https=)
SG (1) SG11201901371XA (https=)
WO (1) WO2018039463A1 (https=)

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US11319594B2 (en) * 2016-08-25 2022-05-03 Resolution Bioscience, Inc. Methods for the detection of genomic copy changes in DNA samples
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CA3118304A1 (en) * 2018-11-02 2020-05-07 The Regents Of The University Of California Methods to diagnose and treat cancer using non-human nucleic acids
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MX2021013834A (es) * 2019-05-17 2022-06-29 Univ Johns Hopkins Detección rápida de aneuploidía.
CA3147613A1 (en) * 2019-08-19 2021-02-25 Chang-Seok Ki Method for detecting chromosomal abnormality by using information about distance between nucleic acid fragments
KR102452413B1 (ko) * 2019-08-19 2022-10-11 주식회사 지씨지놈 핵산 단편간 거리 정보를 이용한 염색체 이상 검출 방법
KR102184277B1 (ko) * 2020-01-16 2020-11-30 성균관대학교산학협력단 초음파 진단 및 dna 검사 일체형 ai 자가 건강 관리 장치 및 이를 이용한 원격 의료 진단 방법
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US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
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CN113113085B (zh) * 2021-03-15 2022-08-19 杭州杰毅生物技术有限公司 基于智能宏基因组测序数据肿瘤检测的分析系统及方法
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