CA3030208A1 - Novel alkaline stable immunoglobulin binding proteins - Google Patents

Novel alkaline stable immunoglobulin binding proteins Download PDF

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Publication number
CA3030208A1
CA3030208A1 CA3030208A CA3030208A CA3030208A1 CA 3030208 A1 CA3030208 A1 CA 3030208A1 CA 3030208 A CA3030208 A CA 3030208A CA 3030208 A CA3030208 A CA 3030208A CA 3030208 A1 CA3030208 A1 CA 3030208A1
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CA
Canada
Prior art keywords
amino acid
binding
seq
binding protein
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3030208A
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English (en)
French (fr)
Inventor
Paul KNICK
Erik Fiedler
Ulrich Haupts
Maren MEYSING
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Navigo Proteins GmbH
Original Assignee
Navigo Proteins GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Navigo Proteins GmbH filed Critical Navigo Proteins GmbH
Publication of CA3030208A1 publication Critical patent/CA3030208A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CA3030208A 2016-08-11 2017-08-07 Novel alkaline stable immunoglobulin binding proteins Pending CA3030208A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16183710.9 2016-08-11
EP16183710 2016-08-11
EP16205707 2016-12-21
EP16205707.9 2016-12-21
PCT/EP2017/069976 WO2018029157A1 (en) 2016-08-11 2017-08-07 Novel alkaline stable immunoglobulin-binding proteins

Publications (1)

Publication Number Publication Date
CA3030208A1 true CA3030208A1 (en) 2018-02-15

Family

ID=59631752

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3030208A Pending CA3030208A1 (en) 2016-08-11 2017-08-07 Novel alkaline stable immunoglobulin binding proteins
CA3031858A Pending CA3031858A1 (en) 2016-08-11 2017-08-07 Alkaline stable fc-binding proteins for affinity chromatography

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3031858A Pending CA3031858A1 (en) 2016-08-11 2017-08-07 Alkaline stable fc-binding proteins for affinity chromatography

Country Status (11)

Country Link
US (4) US11230576B2 (https=)
EP (4) EP3497117B1 (https=)
JP (3) JP7181612B2 (https=)
KR (3) KR102578256B1 (https=)
CN (4) CN109963864B (https=)
AU (2) AU2017311542B2 (https=)
CA (2) CA3030208A1 (https=)
DK (1) DK3497117T5 (https=)
LT (1) LT3497117T (https=)
SG (1) SG11201901066UA (https=)
WO (2) WO2018029158A1 (https=)

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Publication number Publication date
KR20190038560A (ko) 2019-04-08
US11230576B2 (en) 2022-01-25
EP3497118B1 (en) 2022-09-14
CA3031858A1 (en) 2018-02-15
JP2019527715A (ja) 2019-10-03
US20250051400A1 (en) 2025-02-13
AU2017311541B2 (en) 2020-08-13
SG11201901066UA (en) 2019-03-28
CN116333065A (zh) 2023-06-27
KR20190044059A (ko) 2019-04-29
US20190300568A1 (en) 2019-10-03
AU2017311542A1 (en) 2019-02-07
EP4324840A3 (en) 2024-04-24
KR20230133943A (ko) 2023-09-19
EP3497117B1 (en) 2024-01-24
CN109963864A (zh) 2019-07-02
AU2017311541A1 (en) 2019-02-21
JP2022160444A (ja) 2022-10-19
EP3497118A1 (en) 2019-06-19
WO2018029158A1 (en) 2018-02-15
EP4324840A2 (en) 2024-02-21
CN117736281A (zh) 2024-03-22
CN109476712A (zh) 2019-03-15
JP2019531055A (ja) 2019-10-31
JP6951417B2 (ja) 2021-10-20
AU2017311542B2 (en) 2021-06-24
US11014967B2 (en) 2021-05-25
KR102578256B1 (ko) 2023-09-15
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