CA3012791C - Use of gabaa receptor modulators for treatment of itch - Google Patents
Use of gabaa receptor modulators for treatment of itch Download PDFInfo
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- CA3012791C CA3012791C CA3012791A CA3012791A CA3012791C CA 3012791 C CA3012791 C CA 3012791C CA 3012791 A CA3012791 A CA 3012791A CA 3012791 A CA3012791 A CA 3012791A CA 3012791 C CA3012791 C CA 3012791C
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- itch
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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| CA3222584A CA3222584A1 (en) | 2016-01-27 | 2017-01-27 | Use of gabaa receptor modulators for treatment of itch |
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| EP16153035.7 | 2016-01-27 | ||
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| EP16178824.5 | 2016-07-11 | ||
| PCT/EP2017/051866 WO2017129801A1 (en) | 2016-01-27 | 2017-01-27 | Use of gabaa receptor modulators for treatment of itch |
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| CA3222584A Division CA3222584A1 (en) | 2016-01-27 | 2017-01-27 | Use of gabaa receptor modulators for treatment of itch |
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| CA3012791A1 CA3012791A1 (en) | 2017-08-03 |
| CA3012791C true CA3012791C (en) | 2024-01-23 |
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| MX388862B (es) | 2016-01-27 | 2025-03-20 | Univ Zuerich | Uso de moduladores de receptores de gabaa para el tratamiento de picor. |
| JP7449272B2 (ja) | 2018-04-18 | 2024-03-13 | ニューロサイクル・セラピューティクス・インコーポレイテッド | Ｇａｂａａ陽性アロステリックモジュレーター化合物、その作製の方法および使用 |
| EP3796907A4 (en) | 2018-05-22 | 2021-11-03 | Neurocycle Therapeutics, Inc. | GABAA POSITIVE ALLOSTERIC MODULATING COMPOUNDS FOR THE TREATMENT OF PRURITUS AND / OR DERMATITIS |
| LT3849976T (lt) | 2018-09-13 | 2023-02-10 | Saniona A/S | Gaba a receptoriaus ligandas |
| CA3132810A1 (en) * | 2019-03-18 | 2020-09-24 | Neurocycle Therapeutics, Inc. | Use of gabaa receptor modulators for treatment of fybromyalgia |
| CN110004118B (zh) * | 2019-03-29 | 2023-03-28 | 中国科学院武汉物理与数学研究所 | 用于辅助重组狂犬病毒在神经细胞高效逆向跨单级突触的rAAV病毒的包装方法及其应用 |
| CA3155618A1 (en) * | 2019-10-23 | 2021-04-29 | Jed Hubbs | Treatment of epileptic conditions with gabaa receptor modulators |
| US12233070B2 (en) * | 2020-06-30 | 2025-02-25 | University Of Mississippi Medical Center | Methods for treating benzodiazepine misuse/use disorder |
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| IL127911A0 (en) | 1996-07-25 | 1999-11-30 | Merck Sharp & Dohme | Substituted triazolo-pyridazine derivatives as ligands for gaba receptors |
| FR2767692B1 (fr) * | 1997-09-01 | 2000-03-03 | Oreal | Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles |
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| PT2054416E (pt) | 2006-08-04 | 2011-04-06 | Merz Pharma Gmbh & Co Kgaa | Pirazolopirimidinas substituídas, um processo para a sua preparação e a sua utilização como medicamento |
| EP2497470B8 (en) | 2006-11-22 | 2015-12-02 | Incyte Holdings Corporation | Imidazotriazines and imidazopyrimidines as kinase inhibitors |
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| NZ589622A (en) | 2008-05-21 | 2012-10-26 | Incyte Corp | Salts of 2-fluoro-N-methyl-4-[7-(quinolin-6-yl-methyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same |
| WO2010063487A1 (en) | 2008-12-05 | 2010-06-10 | Merz Pharma Gmbh & Co. Kgaa | Pyrazolopyrimidines, a process for their preparation and their use as medicine |
| RU2549547C2 (ru) | 2009-04-22 | 2015-04-27 | Янссен Фармацевтика Нв | Азетидинилдиамиды в качестве ингибиторов моноацилглицерин-липазы |
| EP2456311A4 (en) | 2009-07-24 | 2013-01-23 | Concert Pharmaceuticals Inc | SUBSTITUTED IMIDASOTRIAZINES |
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| MX353336B (es) * | 2013-02-19 | 2018-01-09 | Ono Pharmaceutical Co | Compuesto inhibidor de cinasa del receptor de tropomiosina (trk). |
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| WO2016154031A1 (en) | 2015-03-20 | 2016-09-29 | Uwm Research Foundation, Inc. | Gabaergic ligands and their uses |
| MX388862B (es) | 2016-01-27 | 2025-03-20 | Univ Zuerich | Uso de moduladores de receptores de gabaa para el tratamiento de picor. |
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| BR112018015386A2 (pt) | 2019-03-19 |
| UA125463C2 (uk) | 2022-03-16 |
| US12433898B2 (en) | 2025-10-07 |
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| CA3222584A1 (en) | 2017-08-03 |
| WO2017129801A1 (en) | 2017-08-03 |
| AU2017213154B2 (en) | 2023-02-02 |
| CA3012791A1 (en) | 2017-08-03 |
| AU2017213154A1 (en) | 2018-08-16 |
| IL260775B (en) | 2021-09-30 |
| JP2022088620A (ja) | 2022-06-14 |
| US20250268912A1 (en) | 2025-08-28 |
| MX2018009252A (es) | 2019-01-21 |
| MX388862B (es) | 2025-03-20 |
| CL2018002023A1 (es) | 2019-02-01 |
| US10786513B2 (en) | 2020-09-29 |
| RU2018128905A (ru) | 2020-02-27 |
| EP3407886A1 (en) | 2018-12-05 |
| US20210100814A1 (en) | 2021-04-08 |
| JP2019507736A (ja) | 2019-03-22 |
| JP7115746B2 (ja) | 2022-08-09 |
| CN108697694B (zh) | 2022-12-09 |
| KR102482200B1 (ko) | 2022-12-27 |
| CN108697694A (zh) | 2018-10-23 |
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