CA3005158A1 - Anti-pro/latent-myostatin antibodies and uses thereof - Google Patents
Anti-pro/latent-myostatin antibodies and uses thereof Download PDFInfo
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- CA3005158A1 CA3005158A1 CA3005158A CA3005158A CA3005158A1 CA 3005158 A1 CA3005158 A1 CA 3005158A1 CA 3005158 A CA3005158 A CA 3005158A CA 3005158 A CA3005158 A CA 3005158A CA 3005158 A1 CA3005158 A1 CA 3005158A1
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| US201562100361P | 2015-01-06 | 2015-01-06 | |
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| US201562187348P | 2015-07-01 | 2015-07-01 | |
| US62/187,348 | 2015-07-01 | ||
| US201562219094P | 2015-09-15 | 2015-09-15 | |
| US62/219,094 | 2015-09-15 | ||
| PCT/US2015/059468 WO2016073853A1 (en) | 2014-11-06 | 2015-11-06 | Anti-pro/latent-myostatin antibodies and uses thereof |
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| BRPI0817294A2 (pt) | 2007-09-26 | 2015-03-17 | Chugai Pharmaceutical Co Ltd | Método de modificação do ponto isoelétrico de anticorpo via substituição de aminoácido em cdr. |
| EP3056513A1 (en) | 2008-04-11 | 2016-08-17 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| KR102568454B1 (ko) | 2010-11-30 | 2023-08-18 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복해서 결합하는 항원 결합 분자 |
| EP2889376A4 (en) | 2012-08-24 | 2016-11-02 | Chugai Pharmaceutical Co Ltd | MOUSE FC RII SPECIFIC FC ANTIBODY |
| TW202237660A (zh) | 2012-08-24 | 2022-10-01 | 日商中外製藥股份有限公司 | FcγRIIb特異性Fc區域變異體 |
| WO2014163101A1 (ja) | 2013-04-02 | 2014-10-09 | 中外製薬株式会社 | Ｆｃ領域改変体 |
| PL2981822T3 (pl) * | 2013-05-06 | 2021-07-12 | Scholar Rock, Inc. | Kompozycje i sposoby modulacji czynnika wzrostu |
| US10307480B2 (en) | 2014-11-06 | 2019-06-04 | Scholar Rock, Inc. | Anti-pro/latent-myostatin antibodies and uses thereof |
| EP4600372A3 (en) | 2014-12-19 | 2025-11-19 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
| KR102605798B1 (ko) | 2015-02-05 | 2023-11-23 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용 |
| PT3653221T (pt) | 2015-02-19 | 2022-11-08 | Compugen Ltd | Anticorpos anti-pvrig e métodos de utilização |
| HRP20250666T1 (hr) | 2015-09-15 | 2025-08-01 | Scholar Rock, Inc. | Anti-pro/latentna miostatinska protutijela i njihove uporabe |
| KR101820637B1 (ko) * | 2015-12-18 | 2018-01-19 | 추가이 세이야쿠 가부시키가이샤 | 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법 |
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| CN109071645A (zh) | 2016-01-08 | 2018-12-21 | 供石公司 | 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法 |
| DK3368069T3 (da) * | 2016-06-13 | 2020-11-02 | Scholar Rock Inc | Anvendelse af myostatininhibitorer og kombinationsterapier |
| CN109311969B (zh) * | 2016-06-17 | 2022-09-27 | 中外制药株式会社 | 抗-肌肉生长抑制因子抗体及使用方法 |
| US11053308B2 (en) | 2016-08-05 | 2021-07-06 | Chugai Seiyaku Kabushiki Kaisha | Method for treating IL-8-related diseases |
| DK3565592T5 (da) * | 2017-01-06 | 2024-09-02 | Scholar Rock Inc | Behandling af stofskiftesygdomme ved inhibering af myostatinaktivering |
| PT3565592T (pt) | 2017-01-06 | 2023-05-31 | Scholar Rock Inc | Tratamento de doenças metabólicas através da inibição da ativação da miostatina |
| MA52165A (fr) | 2018-07-11 | 2021-06-02 | Scholar Rock Inc | Inhibiteurs sélectifs de l'isoforme tgfbeta1 et utilisation associée |
| CN112996535A (zh) | 2018-07-11 | 2021-06-18 | 供石公司 | 高亲和性、亚型选择性TGFβ1抑制剂及其用途 |
| WO2022204581A2 (en) | 2021-03-26 | 2022-09-29 | Scholar Rock, Inc. | Tgf-beta inhibitors and use thereof |
| WO2022256723A2 (en) | 2021-06-03 | 2022-12-08 | Scholar Rock, Inc. | Tgf-beta inhibitors and therapeutic use thereof |
| JP2024524159A (ja) | 2021-06-23 | 2024-07-05 | スカラー ロック インコーポレイテッド | 代謝障害の治療における使用のためのｇｌｐ－１経路活性化剤と組み合わせたミオスタチン経路阻害剤 |
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