CA2982873A1 - Arenaviruses for use in the treatment and/or prevention of tumors - Google Patents
Arenaviruses for use in the treatment and/or prevention of tumorsInfo
- Publication number
- CA2982873A1 CA2982873A1 CA2982873A CA2982873A CA2982873A1 CA 2982873 A1 CA2982873 A1 CA 2982873A1 CA 2982873 A CA2982873 A CA 2982873A CA 2982873 A CA2982873 A CA 2982873A CA 2982873 A1 CA2982873 A1 CA 2982873A1
- Authority
- CA
- Canada
- Prior art keywords
- arenavirus
- virus
- carcinoma
- tumor
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| DE102015207036.0 | 2015-04-17 | ||
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| PCT/EP2016/058347 WO2016166285A1 (de) | 2015-04-17 | 2016-04-15 | Arenaviren zur anwendung bei der behandlung und/oder vorbeugung von tumoren sowie verfahren zur herstellung von arenaviren mit (verbesserten) tumorregressiven eigenschaften |
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| EP3218504B1 (en) | 2014-11-13 | 2020-07-22 | Université de Genève | Tri-segmented arenaviruses as vaccine vectors |
| DE102015207036A1 (de) | 2015-04-17 | 2016-10-20 | Karl Sebastian Lang | Arenaviren zur Anwendung bei der Behandlung und/oder Vorbeugung von Tumoren sowie Verfahren zur Herstellung von Arenaviren mit (verbesserten) tumorregressiven Eigenschaften |
| CA2987155A1 (en) | 2015-06-10 | 2016-12-15 | Hookipa Biotech Ag | Hpv vaccines |
| CA3003557A1 (en) | 2015-11-04 | 2017-05-11 | Hookipa Biotech Ag | Vaccines against hepatitis b virus |
| US11266727B2 (en) | 2015-11-12 | 2022-03-08 | Hookipa Biotech Gmbh | Arenavirus particles as cancer vaccines |
| EP3606549A1 (en) * | 2017-04-07 | 2020-02-12 | Hookipa Biotech GmbH | Arenavirus particles to treat solid tumors |
| DE102018215551A1 (de) * | 2018-09-12 | 2020-03-12 | Virolutions Biotech Gmbh | Verfahren zur Herstellung eines antitumoralen Arenavirus sowie Arenavirusmutanten |
| WO2022180203A1 (en) | 2021-02-26 | 2022-09-01 | Abalos Therapeutics Gmbh | New virus particles for therapeutic purposes |
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| DE102004034461B4 (de) | 2004-07-16 | 2008-02-07 | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus | Gentherapie solider Tumore durch retrovirale, mit Arenavirus-Glykoprotein pseudotypisierte Vektoren |
| US7994221B2 (en) | 2004-12-06 | 2011-08-09 | Siga Technologies, Inc. | Sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses |
| CN103255169A (zh) | 2007-12-27 | 2013-08-21 | 苏黎士大学 | 复制缺陷型沙粒病毒载体 |
| WO2011056993A1 (en) * | 2009-11-04 | 2011-05-12 | Yale University | Compositions and methods for treating cancer with attenuated oncolytic viruses |
| DE102015207036A1 (de) | 2015-04-17 | 2016-10-20 | Karl Sebastian Lang | Arenaviren zur Anwendung bei der Behandlung und/oder Vorbeugung von Tumoren sowie Verfahren zur Herstellung von Arenaviren mit (verbesserten) tumorregressiven Eigenschaften |
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| CN108025054A (zh) | 2018-05-11 |
| US12409217B2 (en) | 2025-09-09 |
| EP3283104A1 (de) | 2018-02-21 |
| JP7273102B2 (ja) | 2023-05-12 |
| DE102015207036A1 (de) | 2016-10-20 |
| CN108025054B (zh) | 2022-12-23 |
| US20190151436A1 (en) | 2019-05-23 |
| ES3017684T3 (en) | 2025-05-13 |
| JP7039037B2 (ja) | 2022-03-22 |
| EP3283104C0 (de) | 2024-12-11 |
| US20180117137A1 (en) | 2018-05-03 |
| WO2016166285A1 (de) | 2016-10-20 |
| BR112017022022A8 (pt) | 2023-03-07 |
| JP2021129589A (ja) | 2021-09-09 |
| BR112017022022A2 (pt) | 2019-01-22 |
| US11801294B2 (en) | 2023-10-31 |
| JP2018515130A (ja) | 2018-06-14 |
| US20240252611A1 (en) | 2024-08-01 |
| EP3283104B1 (de) | 2024-12-11 |
| HK1251168A1 (zh) | 2019-01-25 |
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