CA2981979A1 - Egfr-directed car therapy for glioblastoma - Google Patents
Egfr-directed car therapy for glioblastoma Download PDFInfo
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- CA2981979A1 CA2981979A1 CA2981979A CA2981979A CA2981979A1 CA 2981979 A1 CA2981979 A1 CA 2981979A1 CA 2981979 A CA2981979 A CA 2981979A CA 2981979 A CA2981979 A CA 2981979A CA 2981979 A1 CA2981979 A1 CA 2981979A1
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| CN108261426B (zh) * | 2017-01-04 | 2019-04-05 | 杭州康万达医药科技有限公司 | 药物组合物及其在治疗肿瘤和/或癌症的药物中的应用 |
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| WO2018182511A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| CN107354199A (zh) * | 2017-07-04 | 2017-11-17 | 武汉波睿达生物科技有限公司 | 一种检测靶向cd30的cart细胞中car表达的荧光定量试剂盒 |
| CN107759701B (zh) * | 2017-10-27 | 2021-07-02 | 杭州优善生物科技有限公司 | 嵌合抗原受体、其修饰的NK细胞、编码DNA、mRNA、表达载体、制备方法和应用 |
| CN109836497A (zh) * | 2017-11-25 | 2019-06-04 | 深圳宾德生物技术有限公司 | 一种靶向egfr的单链抗体、嵌合抗原受体t细胞及其制备方法和应用 |
| CN108315305B (zh) * | 2017-12-26 | 2020-11-06 | 沣潮医药科技（上海）有限公司 | 携带嵌合抗原受体的免疫细胞外泌体的制备方法及其应用 |
| AU2019219454A1 (en) | 2018-02-09 | 2020-08-27 | National University Of Singapore | Activating chimeric receptors and uses thereof in natural killer cell immunotherapy |
| SG11202008976YA (en) | 2018-04-02 | 2020-10-29 | Nat Univ Singapore | Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells |
| JP7560882B2 (ja) | 2018-08-29 | 2024-10-03 | ナショナル ユニヴァーシティー オブ シンガポール | 遺伝子修飾免疫細胞の生存及び増加を特異的に刺激するための方法 |
| CN109568351B (zh) * | 2018-11-30 | 2020-02-21 | 武汉波睿达生物科技有限公司 | 溶瘤病毒和car-t联合应用针对实体肿瘤的治疗 |
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| CN110592024A (zh) * | 2019-09-12 | 2019-12-20 | 广东食品药品职业学院 | 以tEGFR与CD19为双靶点的CAR-NK细胞制备方法及其应用 |
| CN110845623B (zh) * | 2019-10-11 | 2021-07-09 | 厦门大学 | 一种egfr特异性嵌合抗原受体及其应用 |
| JP7727326B6 (ja) * | 2020-01-19 | 2025-09-08 | 北京▲峠▼替医療技術有限公司 | 免疫細胞の機能を向上させる強化受容体 |
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| CN111925448B (zh) * | 2020-08-03 | 2022-06-21 | 山东大学 | 在体生成car-巨噬细胞的制备方法及肿瘤免疫治疗中的应用 |
| MX2023002887A (es) * | 2020-09-10 | 2023-08-16 | Mustang Bio Inc | Terapia combinada que comprende células t del receptor de antígenos quiméricos (car) dirigidas al cáncer y un método para utilizar las mismas para un tratamiento para el cáncer. |
| WO2022068870A1 (zh) * | 2020-09-30 | 2022-04-07 | 中国科学院动物研究所 | 靶向egfr的嵌合抗原受体 |
| WO2023034758A1 (en) * | 2021-08-30 | 2023-03-09 | Cytoimmune Therapeutics, Inc. | Methods and compositions for cell expansion |
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| CA3205751A1 (en) | 2012-02-22 | 2013-08-29 | The Trustees Of The University Of Pennsylvania | Use of icos-based cars to enhance antitumor activity and car persistence |
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| US20140302037A1 (en) | 2013-03-15 | 2014-10-09 | Amgen Inc. | BISPECIFIC-Fc MOLECULES |
| AU2014259675B2 (en) * | 2013-05-03 | 2019-05-02 | Ohio State Innovation Foundation | CS1-specific chimeric antigen receptor engineered immune effector cells |
| US9517276B2 (en) * | 2013-06-04 | 2016-12-13 | Cytomx Therapeutics, Inc. | Compositions and methods for conjugating activatable antibodies |
| AU2014337367B2 (en) | 2013-10-15 | 2020-04-30 | The Scripps Research Institute | Peptidic chimeric antigen receptor T cell switches and uses thereof |
| EP3831398A1 (en) | 2013-10-25 | 2021-06-09 | PsiOxus Therapeutics Limited | Oncolytic adenoviruses armed with heterologous genes |
| WO2015142675A2 (en) | 2014-03-15 | 2015-09-24 | Novartis Ag | Treatment of cancer using chimeric antigen receptor |
| JP7054622B2 (ja) | 2014-07-21 | 2022-04-14 | ノバルティス アーゲー | ヒト化抗ｂｃｍａキメラ抗原受容体を使用した癌の処置 |
| US10973914B2 (en) | 2015-02-20 | 2021-04-13 | Ohio State Innovation Foundation | Bivalent antibody directed against NKG2D and tumor associated antigens |
| EP3270937A4 (en) | 2015-03-26 | 2018-09-12 | The Trustees Of Dartmouth College | Anti-mica antigen binding fragments, fusion molecules, cells which express and methods of using |
| MA44314A (fr) | 2015-11-05 | 2018-09-12 | Juno Therapeutics Inc | Récepteurs chimériques contenant des domaines induisant traf, et compositions et méthodes associées |
| EP3504245A4 (en) | 2016-08-23 | 2020-04-22 | The Regents of The University of California | PROTEOLYTICLY CLEAVABLE CHIMERAL POLYPEPTIDES AND METHOD FOR USE THEREOF |
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2016
- 2016-04-05 JP JP2017553189A patent/JP6879932B2/ja not_active Expired - Fee Related
- 2016-04-05 WO PCT/US2016/026057 patent/WO2016164370A1/en not_active Ceased
- 2016-04-05 HK HK18110330.8A patent/HK1250918A1/zh unknown
- 2016-04-05 CN CN201680025143.5A patent/CN108367057B/zh not_active Expired - Fee Related
- 2016-04-05 KR KR1020177031930A patent/KR20180012749A/ko not_active Ceased
- 2016-04-05 AU AU2016246457A patent/AU2016246457B2/en not_active Ceased
- 2016-04-05 US US15/564,166 patent/US11045543B2/en not_active Expired - Fee Related
- 2016-04-05 EP EP16777143.5A patent/EP3280437A4/en not_active Withdrawn
- 2016-04-05 CA CA2981979A patent/CA2981979A1/en active Pending
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2020
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2021
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|---|---|
| EP3280437A1 (en) | 2018-02-14 |
| CN108367057A (zh) | 2018-08-03 |
| EP3280437A4 (en) | 2018-09-12 |
| US11045543B2 (en) | 2021-06-29 |
| KR20180012749A (ko) | 2018-02-06 |
| AU2016246457A1 (en) | 2017-10-26 |
| JP2020156522A (ja) | 2020-10-01 |
| AU2016246457B2 (en) | 2020-10-15 |
| HK1250918A1 (zh) | 2019-01-18 |
| US20180117146A1 (en) | 2018-05-03 |
| WO2016164370A1 (en) | 2016-10-13 |
| JP6879932B2 (ja) | 2021-06-02 |
| CN108367057B (zh) | 2022-11-22 |
| US20210308261A1 (en) | 2021-10-07 |
| JP2018513687A (ja) | 2018-05-31 |
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