CA2975568A1 - Antibody-mediated disruption of quorum sensing in bacteria - Google Patents
Antibody-mediated disruption of quorum sensing in bacteria Download PDFInfo
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- CA2975568A1 CA2975568A1 CA2975568A CA2975568A CA2975568A1 CA 2975568 A1 CA2975568 A1 CA 2975568A1 CA 2975568 A CA2975568 A CA 2975568A CA 2975568 A CA2975568 A CA 2975568A CA 2975568 A1 CA2975568 A1 CA 2975568A1
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Classifications
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
-
- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
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- Mycology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98259307P | 2007-10-25 | 2007-10-25 | |
| US60/982,593 | 2007-10-25 | ||
| CA2703133A CA2703133C (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2703133A Division CA2703133C (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| CA2975568A1 true CA2975568A1 (en) | 2009-04-30 |
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| CA2975568A Abandoned CA2975568A1 (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
| CA2703133A Active CA2703133C (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2703133A Active CA2703133C (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
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| US (2) | US9394371B2 (OSRAM) |
| EP (2) | EP2842565B1 (OSRAM) |
| JP (3) | JP5581490B2 (OSRAM) |
| KR (1) | KR101557173B1 (OSRAM) |
| CN (2) | CN101835484B (OSRAM) |
| AU (1) | AU2008317331B2 (OSRAM) |
| CA (2) | CA2975568A1 (OSRAM) |
| ES (1) | ES2603061T3 (OSRAM) |
| WO (1) | WO2009055054A2 (OSRAM) |
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| EP2911694A4 (en) | 2012-10-26 | 2016-07-13 | Sorrento Therapeutics Inc | ANTI-INFECTIOUS BINDING PROTEINS THAT BIND TO AIP2 |
| DE102013211850A1 (de) * | 2013-06-21 | 2014-12-24 | Gilupi Gmbh | Schnelltest zum Nachweisen von Erregermaterial, insbesondere zur Unterstützung der Diagnose einer Sepsis, sowie Kit und Vorrichtung zur Durchführung eines Sepsistests |
| SG10201800889SA (en) * | 2013-08-01 | 2018-03-28 | Univ Catholique Louvain | Anti-garp protein and uses thereof |
| WO2015100225A1 (en) | 2013-12-27 | 2015-07-02 | Novus International Inc. | Ethoxylated surfactants |
| PT3101132T (pt) * | 2014-01-29 | 2021-12-31 | Km Biologics Co Ltd | Anticorpo humano anti-transtirretina |
| CN106574258B (zh) | 2014-01-29 | 2021-03-30 | Km生物医药股份公司 | 抗-运甲状腺素蛋白人源化抗体 |
| EP3103808B1 (en) * | 2014-02-07 | 2018-08-22 | Miyarisan Pharmaceutical Co., Ltd. | Peptide having activity of inhibiting production of toxin by bacterium belonging to genus clostridium |
| US10821167B2 (en) * | 2016-02-02 | 2020-11-03 | Unm Rainforest Innovations | VLP-based vaccines for targeting Staphylococcus aureus secreted virulence factors |
| JP7058638B2 (ja) * | 2016-08-11 | 2022-04-22 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | ホスホグリセリン酸ムターゼのペプチド阻害剤および使用方法 |
| AU2018221172A1 (en) * | 2017-02-17 | 2019-09-05 | Adimab, Llc | Monoclonal antibodies and cocktails for treatment of Ebola infections |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
| BR112020003508A2 (pt) * | 2017-08-31 | 2020-09-01 | The Regents Of The University Of California | polipeptídeo purificado, formulação tópica, polinucleotídeo isolado, vetor, microrganismo recombinante, composição probiótica tópica, composição medicamentosa, e, métodos de tratamento de um transtorno dermatológico, de tratamento de uma doença ou transtorno de pele e para liberação de fármacos através da pele. |
| US10501539B2 (en) | 2017-09-15 | 2019-12-10 | Lentigen Technology Inc. | Compositions and methods for treating cancer with anti-CD19 immunotherapy |
| US10774135B2 (en) | 2017-12-22 | 2020-09-15 | Sorrento Therapeutics, Inc. | Variant antibodies that bind AIP2 |
| WO2019159864A1 (ja) | 2018-02-13 | 2019-08-22 | 住友化学株式会社 | 組成物および成形体 |
| WO2021030550A1 (en) | 2019-08-13 | 2021-02-18 | Mccord Darlene E | NON-ACTIVATED, AMORPHOUS, pH NEUTRAL, TWO-PART BEDSIDE-READY CLAY DELIVERY SYSTEM THAT TREATS PATHOGEN INFECTIONS IN HUMANS AND ANIMALS |
| CN111573853B (zh) * | 2020-05-29 | 2020-11-20 | 南京大学 | 一种削减生物法处理废水毒性的方法 |
| EP4423197A4 (en) | 2021-10-25 | 2025-08-27 | Darlene E Mccord | COATED MEDICINAL CLAY COMPOSITIONS, PHARMACEUTICAL COMPOSITIONS AND DELIVERY OF CATION SOURCES AND METHODS OF USE THEREOF |
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| DE69732709T2 (de) * | 1996-05-22 | 2006-06-29 | New York University | Expressionsblockierung von virulenten faktoren in s. aureus |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| JP2003532698A (ja) * | 2000-05-10 | 2003-11-05 | プリンストン ユニバーシティ | 細菌の増殖および病理発生を調節するための化合物ならびに方法 |
| US7786257B2 (en) * | 2000-12-18 | 2010-08-31 | University Of Kansas | Signal-1/signal-2 bifunctional peptide inhibitors |
| US6463632B2 (en) * | 2001-02-07 | 2002-10-15 | Hans Oetiker Ag Maschinen-Und Apparatefabrik | Guide arrangement for tightening tool emplacement in hose clamps provided with plastically deformable ears |
| CN1164612C (zh) | 2001-09-11 | 2004-09-01 | 四川新泰克控股有限责任公司 | 人工组合的抗菌工程多肽及其制备方法 |
| ES2382075T3 (es) * | 2002-08-13 | 2012-06-05 | Haptogen Ltd | Procedimientos para el tratamiento de una enfermedad bacteriana infecciosa con un anticuerpo contra las moléculas señal derivadas de una antilactona o una lactona |
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2008
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2014
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2017
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2211889B1 (en) | 2014-08-20 |
| EP2842565B1 (en) | 2016-08-24 |
| US20100291093A1 (en) | 2010-11-18 |
| EP2211889A4 (en) | 2012-01-11 |
| US20170043020A1 (en) | 2017-02-16 |
| KR20100102100A (ko) | 2010-09-20 |
| US9394371B2 (en) | 2016-07-19 |
| WO2009055054A3 (en) | 2009-09-03 |
| EP2842565A1 (en) | 2015-03-04 |
| KR101557173B1 (ko) | 2015-10-05 |
| JP6183910B2 (ja) | 2017-08-23 |
| ES2603061T3 (es) | 2017-02-23 |
| CA2703133A1 (en) | 2009-04-30 |
| CN101835484B (zh) | 2014-07-16 |
| WO2009055054A2 (en) | 2009-04-30 |
| AU2008317331B2 (en) | 2013-08-29 |
| CN104211775A (zh) | 2014-12-17 |
| JP2014221774A (ja) | 2014-11-27 |
| JP5581490B2 (ja) | 2014-09-03 |
| JP2018021021A (ja) | 2018-02-08 |
| CN101835484A (zh) | 2010-09-15 |
| EP2211889A2 (en) | 2010-08-04 |
| AU2008317331A1 (en) | 2009-04-30 |
| JP2011500814A (ja) | 2011-01-06 |
| CA2703133C (en) | 2017-09-19 |
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| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20170802 |
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| FZDE | Discontinued |
Effective date: 20191024 |