CA2972662A1 - Natural killer cells and uses thereof - Google Patents
Natural killer cells and uses thereof Download PDFInfo
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- CA2972662A1 CA2972662A1 CA2972662A CA2972662A CA2972662A1 CA 2972662 A1 CA2972662 A1 CA 2972662A1 CA 2972662 A CA2972662 A CA 2972662A CA 2972662 A CA2972662 A CA 2972662A CA 2972662 A1 CA2972662 A1 CA 2972662A1
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201462098560P | 2014-12-31 | 2014-12-31 | |
| US62/098,560 | 2014-12-31 | ||
| PCT/US2015/068055 WO2016109661A1 (en) | 2014-12-31 | 2015-12-30 | Natural killer cells and uses thereof |
Publications (1)
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| CA2972662A1 true CA2972662A1 (en) | 2016-07-07 |
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| CA2972662A Pending CA2972662A1 (en) | 2014-12-31 | 2015-12-30 | Natural killer cells and uses thereof |
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| EP (1) | EP3240552A4 (enExample) |
| JP (3) | JP2018502115A (enExample) |
| KR (2) | KR20230146101A (enExample) |
| CN (1) | CN107405364A (enExample) |
| AU (2) | AU2015374055A1 (enExample) |
| BR (1) | BR112017014269A2 (enExample) |
| CA (1) | CA2972662A1 (enExample) |
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| IL (1) | IL253248A0 (enExample) |
| NZ (1) | NZ733213A (enExample) |
| WO (1) | WO2016109661A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3898951A4 (en) * | 2018-12-21 | 2022-08-31 | Stemcell Technologies Canada Inc. | MATERIALS AND METHODS FOR DIFFERENTIATING NATURAL KILLER CELLS |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014117121A1 (en) | 2013-01-28 | 2014-07-31 | St. Jude Children's Research Hospital, Inc. | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| CA2948462A1 (en) | 2014-05-15 | 2015-11-19 | National University Of Singapore | Modified natural killer cells and uses thereof |
| ES2980858T3 (es) * | 2015-09-15 | 2024-10-03 | Stichting Radboud Univ Medisch Centrum | Método mejorado para la expansión ex vivo de HSPC CD34+ en células NK usando un antagonista del receptor de aril hidrocarburos |
| JP2018535666A (ja) * | 2015-10-15 | 2018-12-06 | セルラリティ インコーポレイテッド | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
| US20200179341A1 (en) * | 2016-11-04 | 2020-06-11 | Ohio State Innovation Foundation | Methods and compositions for treating multiple myeloma and increasing antibody dependent cell cytotoxicity by targeting the aryl hydrocarbon receptor |
| US20180273903A1 (en) * | 2016-12-30 | 2018-09-27 | Celularity, Inc. | Genetically modified natural killer cells |
| EP3600356A4 (en) | 2017-03-27 | 2020-12-23 | National University of Singapore | TRUNCATED NKG2D CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLER CELL IMMUNOTHERAPY |
| KR102624509B1 (ko) | 2017-03-27 | 2024-01-12 | 싱가포르국립대학교 | 자연 살해 세포의 ex vivo 확장 및 활성화를 위한 자극성 세포주 |
| JP7269917B2 (ja) * | 2017-08-17 | 2023-05-09 | イケナ オンコロジー， インコーポレイテッド | Ａｈｒ阻害剤およびその使用 |
| KR102167548B1 (ko) * | 2017-09-21 | 2020-10-19 | 한국생명공학연구원 | 자연살해세포의 제조방법 및 그의 용도 |
| WO2019059713A2 (ko) * | 2017-09-21 | 2019-03-28 | 한국생명공학연구원 | 자연살해세포의 제조방법 및 그의 용도 |
| JP7360174B2 (ja) | 2018-02-09 | 2023-10-12 | ナショナル ユニヴァーシティー オブ シンガポール | ナチュラルキラー細胞免疫療法における活性化キメラ受容体及びその使用 |
| CA3091865A1 (en) | 2018-02-20 | 2019-08-29 | Universite De Montreal | Expansion of nk and dc cells in vivo mediating immune response |
| JP7334985B2 (ja) | 2018-04-02 | 2023-08-29 | ナショナル ユニヴァーシティー オブ シンガポール | 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和 |
| US12304962B2 (en) | 2018-05-30 | 2025-05-20 | Glycostem Therapeutics B.V. | CAR NK cells |
| CN112601758A (zh) | 2018-08-29 | 2021-04-02 | 新加坡国立大学 | 特异性刺激经基因修饰免疫细胞的存活和扩增的方法 |
| CA3112951A1 (en) * | 2018-10-01 | 2020-04-09 | Universiteit Gent | Accelerated human hematopoietic stem cell differentiation towards mature natural killer cells with enhanced antibody-dependent cytotoxic activity |
| CN109294985B (zh) * | 2018-10-25 | 2022-02-18 | 江苏普瑞康生物医药科技有限公司 | 一种用于nk细胞体外扩增的培养基体系及nk细胞体外扩增的方法 |
| CN113454207A (zh) * | 2018-11-30 | 2021-09-28 | 细胞结构公司 | 用新型芳香族化合物扩增自然杀伤细胞和ilc3细胞 |
| JP7335001B2 (ja) * | 2019-01-18 | 2023-08-29 | アセポディア バイオテクノロジーズ リミテッド | 新規ｃｄ１６＋ナチュラルキラーおよびｃｄ１６＋ナチュラルキラー細胞の培養方法 |
| CN118546959A (zh) | 2019-03-05 | 2024-08-27 | 恩卡尔塔公司 | Cd19定向性嵌合抗原受体及其在免疫疗法中的用途 |
| KR102298640B1 (ko) * | 2019-03-28 | 2021-09-07 | 한국생명공학연구원 | Car 유전자가 도입된 nk 세포의 제조방법 및 그의 용도 |
| CN110079529A (zh) * | 2019-04-28 | 2019-08-02 | 成都美杰赛尔生物科技有限公司 | 用于靶向敲除人NKG2A/KLRC1基因的sgRNA、表达载体、试剂盒及其用途 |
| US20220265712A1 (en) * | 2019-06-14 | 2022-08-25 | Celularity Inc. | Populations of natural killer cells for treating cancers |
| CN113652393B (zh) * | 2020-05-12 | 2023-08-15 | 内蒙古大学 | 一种提高牛胚胎干细胞多能性的方法 |
| US11591381B2 (en) | 2020-11-30 | 2023-02-28 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| CN113046314B (zh) * | 2021-03-30 | 2022-11-25 | 中国科学技术大学 | 一种人脐血或骨髓造血干细胞体外诱导扩增蜕膜样自然杀伤细胞的方法 |
| CN113337466B (zh) * | 2021-07-13 | 2023-03-24 | 杭州原生生物科技有限公司 | 一种无血清nk分化培养基及其制备方法 |
| CN115381959A (zh) * | 2022-09-30 | 2022-11-25 | 上海纳米技术及应用国家工程研究中心有限公司 | 一种治疗肝癌的联合用药 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3358007A1 (en) * | 2010-07-13 | 2018-08-08 | Celularity, Inc. | Methods of generating natural killer cells |
| KR102098122B1 (ko) * | 2012-01-27 | 2020-04-07 | 유니버시떼 드 몬트리얼 | 피리미도[4,5-b]인돌 유도체 및 조혈 줄기 세포의 증식에서의 이의 용도 |
| PL2812011T3 (pl) * | 2012-02-08 | 2020-06-29 | Glycostem Therapeutics B.V. | Różnicowanie komórek NK z komórek hematopoetycznych CD34<sup>+</sup> ex vivo |
| US9175266B2 (en) * | 2012-07-23 | 2015-11-03 | Gamida Cell Ltd. | Enhancement of natural killer (NK) cell proliferation and activity |
| CN105008516A (zh) * | 2012-08-13 | 2015-10-28 | 人类起源公司 | 自然杀伤细胞及其用途 |
-
2015
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- 2015-12-30 BR BR112017014269A patent/BR112017014269A2/pt not_active Application Discontinuation
- 2015-12-30 NZ NZ733213A patent/NZ733213A/en not_active IP Right Cessation
- 2015-12-30 CN CN201580077231.5A patent/CN107405364A/zh active Pending
- 2015-12-30 JP JP2017534937A patent/JP2018502115A/ja active Pending
- 2015-12-30 KR KR1020237033327A patent/KR20230146101A/ko not_active Ceased
- 2015-12-30 CA CA2972662A patent/CA2972662A1/en active Pending
- 2015-12-30 AU AU2015374055A patent/AU2015374055A1/en not_active Abandoned
- 2015-12-30 WO PCT/US2015/068055 patent/WO2016109661A1/en not_active Ceased
- 2015-12-30 KR KR1020177021038A patent/KR20170098938A/ko not_active Ceased
- 2015-12-30 US US15/541,004 patent/US20180008637A1/en not_active Abandoned
- 2015-12-30 EP EP15876255.9A patent/EP3240552A4/en not_active Withdrawn
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2017
- 2017-06-29 IL IL253248A patent/IL253248A0/en unknown
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2020
- 2020-05-18 US US16/876,979 patent/US20200330516A1/en not_active Abandoned
- 2020-12-23 JP JP2020213684A patent/JP2021072786A/ja active Pending
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2021
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2022
- 2022-11-04 JP JP2022176993A patent/JP2023022037A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3898951A4 (en) * | 2018-12-21 | 2022-08-31 | Stemcell Technologies Canada Inc. | MATERIALS AND METHODS FOR DIFFERENTIATING NATURAL KILLER CELLS |
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| US20200330516A1 (en) | 2020-10-22 |
| NZ733213A (en) | 2022-10-28 |
| KR20230146101A (ko) | 2023-10-18 |
| JP2023022037A (ja) | 2023-02-14 |
| WO2016109661A1 (en) | 2016-07-07 |
| KR20170098938A (ko) | 2017-08-30 |
| AU2021282387A1 (en) | 2021-12-23 |
| EA201791443A1 (ru) | 2018-01-31 |
| EP3240552A1 (en) | 2017-11-08 |
| JP2018502115A (ja) | 2018-01-25 |
| JP2021072786A (ja) | 2021-05-13 |
| US20180008637A1 (en) | 2018-01-11 |
| IL253248A0 (en) | 2017-08-31 |
| AU2015374055A1 (en) | 2017-07-20 |
| BR112017014269A2 (pt) | 2018-03-27 |
| CN107405364A (zh) | 2017-11-28 |
| EP3240552A4 (en) | 2018-06-20 |
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