CA2963327A1 - Method for modulating car-induced immune cells activity - Google Patents

Method for modulating car-induced immune cells activity Download PDF

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Publication number
CA2963327A1
CA2963327A1 CA2963327A CA2963327A CA2963327A1 CA 2963327 A1 CA2963327 A1 CA 2963327A1 CA 2963327 A CA2963327 A CA 2963327A CA 2963327 A CA2963327 A CA 2963327A CA 2963327 A1 CA2963327 A1 CA 2963327A1
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Prior art keywords
car
immune cell
imp
domain
inhibitory
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Abandoned
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CA2963327A
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English (en)
French (fr)
Inventor
Philippe Duchateau
Alexandre Juillerat
Laurent Poirot
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Cellectis SA
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Cellectis SA
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    • C12N5/10Cells modified by introduction of foreign genetic material
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    • A61K40/00Cellular immunotherapy
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    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/00Cellular immunotherapy
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    • A61K40/31Chimeric antigen receptors [CAR]
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61K2239/23On/off switch
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/622Single chain antibody (scFv)
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    • C12N2740/10011Retroviridae
    • C12N2740/10041Use of virus, viral particle or viral elements as a vector
    • C12N2740/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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CA2963327A 2014-10-07 2015-10-07 Method for modulating car-induced immune cells activity Abandoned CA2963327A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201470623 2014-10-07
DKPA201470623 2014-10-07
PCT/EP2015/073197 WO2016055551A1 (en) 2014-10-07 2015-10-07 Method for modulating car-induced immune cells activity

Publications (1)

Publication Number Publication Date
CA2963327A1 true CA2963327A1 (en) 2016-04-14

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CA2963327A Abandoned CA2963327A1 (en) 2014-10-07 2015-10-07 Method for modulating car-induced immune cells activity

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US (1) US10472613B2 (cg-RX-API-DMAC7.html)
EP (1) EP3204491A1 (cg-RX-API-DMAC7.html)
JP (1) JP2017531430A (cg-RX-API-DMAC7.html)
KR (1) KR20170068539A (cg-RX-API-DMAC7.html)
CN (1) CN107109368A (cg-RX-API-DMAC7.html)
AU (1) AU2015330017A1 (cg-RX-API-DMAC7.html)
BR (1) BR112017007003A2 (cg-RX-API-DMAC7.html)
CA (1) CA2963327A1 (cg-RX-API-DMAC7.html)
IL (1) IL251429A0 (cg-RX-API-DMAC7.html)
MX (1) MX2017004603A (cg-RX-API-DMAC7.html)
RU (1) RU2017115808A (cg-RX-API-DMAC7.html)
WO (1) WO2016055551A1 (cg-RX-API-DMAC7.html)

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