CA2943478A1 - A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using - Google Patents

A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using Download PDF

Info

Publication number
CA2943478A1
CA2943478A1 CA2943478A CA2943478A CA2943478A1 CA 2943478 A1 CA2943478 A1 CA 2943478A1 CA 2943478 A CA2943478 A CA 2943478A CA 2943478 A CA2943478 A CA 2943478A CA 2943478 A1 CA2943478 A1 CA 2943478A1
Authority
CA
Canada
Prior art keywords
prrsv
nucleic acid
seq
con
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2943478A
Other languages
English (en)
French (fr)
Inventor
William W. LAEGREID
Hiep Lai Xuan VU
Fernando Osorio
Asit K. Pattnaik
Fangrui MA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NuTech Ventures Inc
University of Illinois System
Original Assignee
NuTech Ventures Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NuTech Ventures Inc filed Critical NuTech Ventures Inc
Publication of CA2943478A1 publication Critical patent/CA2943478A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2943478A 2014-03-21 2015-03-25 A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using Abandoned CA2943478A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461968465P 2014-03-21 2014-03-21
US61/968,465 2014-03-21
PCT/IB2015/052214 WO2015140774A1 (en) 2014-03-21 2015-03-25 A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using

Publications (1)

Publication Number Publication Date
CA2943478A1 true CA2943478A1 (en) 2015-09-24

Family

ID=54143830

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2943478A Abandoned CA2943478A1 (en) 2014-03-21 2015-03-25 A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using

Country Status (11)

Country Link
US (3) US10072046B2 (https=)
EP (1) EP3119429A4 (https=)
JP (1) JP6538071B2 (https=)
KR (1) KR20170002393A (https=)
CN (1) CN107635579A (https=)
CA (1) CA2943478A1 (https=)
HK (1) HK1247128A1 (https=)
MX (1) MX378873B (https=)
PH (2) PH12016501854B1 (https=)
RU (1) RU2687150C2 (https=)
WO (1) WO2015140774A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107635579A (zh) * 2014-03-21 2018-01-26 纽泰克温图斯公司 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法
TWI704225B (zh) * 2016-02-18 2020-09-11 美商益農美國公司 豬繁殖與呼吸綜合症疫苗病毒
US20240189418A1 (en) * 2021-03-31 2024-06-13 The Industry & Academic Cooperation In Chungnam National University (Iac) Virus vaccine based on virus surface engineering providing increased immunity
CN118791578B (zh) * 2024-07-29 2024-12-27 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 猪繁殖与呼吸综合征病毒nsp12蛋白的抗原表位、单克隆抗体及应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
KR100388257B1 (ko) 1997-05-06 2003-06-19 스티칭 디엔스트 랜드보위쿤디그 온데조에크 백신 또는 진단방법에서 사용하기 위한 피알알에스 바이러스의 피알알에스브이 항원부위 인식성 펩타이드 서열
DK2251419T3 (da) 1999-04-22 2012-07-02 Us Agriculture Porcint reproduktions- og respirations-syndrom-vaccine baseret på isolat JA-142
US20020012670A1 (en) * 2000-01-26 2002-01-31 Knut Elbers Recombinant attenuation of porcine reproductive and respiratory syndrome (PRRSV)
AR027291A1 (es) * 2000-01-26 2003-03-19 Boehringer Ingelheim Vetmed Atenuacion recombinante de prrsv
ES2343371T3 (es) * 2005-08-30 2010-07-29 Board Of Regents Of The University Of Nebraska Procedimientos y composiciones para la vacunacion de animales con antigenos de vsrrp con una inmunogenicidad mejorada.
CA2630648C (en) * 2005-11-29 2016-01-19 Iowa State University Research Foundation, Inc. Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus (prrsv) and uses thereof
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
US9187731B2 (en) * 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) * 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
EP2620446A1 (en) * 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
CN107635579A (zh) * 2014-03-21 2018-01-26 纽泰克温图斯公司 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法

Also Published As

Publication number Publication date
PH12020550204A1 (en) 2021-01-11
MX378873B (es) 2025-03-11
HK1247128A1 (zh) 2018-09-21
US20170198016A1 (en) 2017-07-13
PH12016501854A1 (en) 2017-01-09
US10072046B2 (en) 2018-09-11
RU2016141287A (ru) 2018-04-26
RU2016141287A3 (https=) 2018-06-07
KR20170002393A (ko) 2017-01-06
PH12016501854B1 (en) 2017-01-09
US11136355B2 (en) 2021-10-05
EP3119429A4 (en) 2018-04-04
JP2017510276A (ja) 2017-04-13
US20200331970A1 (en) 2020-10-22
CN107635579A (zh) 2018-01-26
JP6538071B2 (ja) 2019-07-03
US10738088B2 (en) 2020-08-11
US20190048042A1 (en) 2019-02-14
RU2687150C2 (ru) 2019-05-07
WO2015140774A1 (en) 2015-09-24
EP3119429A1 (en) 2017-01-25
MX2016012276A (es) 2017-06-12

Similar Documents

Publication Publication Date Title
US11136355B2 (en) Non-naturally occurring porcine reproductive and respiratory syndrome virus (PRRSV) and methods of using
RU2519210C2 (ru) Вакцины, содержащие генетические варианты парвовируса собак
CN110551695A (zh) 非洲猪瘟病毒四基因缺失弱毒株及其应用
Kanai et al. Long‐term shedding of hepatitis E virus in the feces of pigs infected naturally, born to sows with and without maternal antibodies
CN112245568B (zh) E184l基因缺失减毒非洲猪瘟病毒株的构建及其作为疫苗的应用
CA2626489C (en) Materials and methods for respiratory disease control in canines
CN103451158B (zh) 用于犬科动物中呼吸系统疾病控制的物质和方法
JP2012519471A (ja) 北米のイヌにおいて広まっているイヌジステンパーウイルスに基づく免疫原性組成物、ワクチンおよび診断法
Yan et al. Insights on genetic characterization and pathogenesis of a GI-19 (QX-like) infectious bronchitis virus isolated in China
JP7703030B2 (ja) 安定細胞株において効率的な増殖を可能にする、アフリカ豚熱ワクチンにおけるゲノム欠失
CN111925994B (zh) 一种dp71l基因缺失的重组非洲猪瘟病毒及其制备方法和应用
KR20150137085A (ko) 안정화된 ｆｍｄｖ 캡시드
Inayoshi et al. Bacterial artificial chromosome-based reverse genetics system for cloning and manipulation of the full-length genome of infectious bronchitis virus
ZA200610012B (en) Reverse genetic system for Rift Valley fever virus and uses thereof
US8063195B2 (en) Mutations in a toll-like receptor motif in the NS4B of classical swine fever virus strain brescia influences virulence in swine
CN112111467B (zh) 一种基因vii型新城疫标记疫苗株及其制备方法与应用
Lai Xuan Vu et al. NON-NATURALLY OCCURRING PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) AND METHODS OF USING
Xuan Vu et al. NON-NATURALLY OCCURRING PORCINE REPRODUCTION AND RESPIRATORY SYNDROME VIRUS (PRRSV) AND METHODS OF USING
KR20220061636A (ko) 신규한 돼지 유행성 설사병 바이러스 및 이를 이용한 돼지 유행성 설사병 예방용 백신 조성물
TWI328039B (https=)
KR102774153B1 (ko) 돼지 유행성 설사병 바이러스의 병원성 부위 및 이를 이용한 병원성 예측 방법
Muniraju Establishment of reverse genetics system for PPR virus to develop recombinant vaccines
CN108642019A (zh) 一种耐胃肠道降解的重组狂犬病口服疫苗毒株及其制备方法
서태영 Clonal Selection of African Swine Fever Virus through Vero Cell Adaptation for Development of a Live Attenuated Vaccine
KR101493613B1 (ko) Ｈ3 말 인플루엔자 ａ 바이러스

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20180201

FZDE Discontinued

Effective date: 20220927