CN107635579A - 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法 - Google Patents

非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法 Download PDF

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Publication number
CN107635579A
CN107635579A CN201580024217.9A CN201580024217A CN107635579A CN 107635579 A CN107635579 A CN 107635579A CN 201580024217 A CN201580024217 A CN 201580024217A CN 107635579 A CN107635579 A CN 107635579A
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Chinese (zh)
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H·L·X·乌
F·奥索里奥
W·W·莱格雷德
A·K·帕特奈克
马方瑞
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NuTech Ventures Inc
University of Illinois System
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NuTech Ventures Inc
University of Illinois System
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580024217.9A 2014-03-21 2015-03-25 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法 Pending CN107635579A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461968465P 2014-03-21 2014-03-21
PCT/IB2015/052214 WO2015140774A1 (en) 2014-03-21 2015-03-25 A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using

Publications (1)

Publication Number Publication Date
CN107635579A true CN107635579A (zh) 2018-01-26

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CN201580024217.9A Pending CN107635579A (zh) 2014-03-21 2015-03-25 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法

Country Status (11)

Country Link
US (3) US10072046B2 (https=)
EP (1) EP3119429A4 (https=)
JP (1) JP6538071B2 (https=)
KR (1) KR20170002393A (https=)
CN (1) CN107635579A (https=)
CA (1) CA2943478A1 (https=)
HK (1) HK1247128A1 (https=)
MX (1) MX378873B (https=)
PH (2) PH12016501854B1 (https=)
RU (1) RU2687150C2 (https=)
WO (1) WO2015140774A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118791578A (zh) * 2024-07-29 2024-10-18 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 猪繁殖与呼吸综合征病毒nsp12蛋白的抗原表位、单克隆抗体及应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107635579A (zh) * 2014-03-21 2018-01-26 纽泰克温图斯公司 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法
TWI704225B (zh) * 2016-02-18 2020-09-11 美商益農美國公司 豬繁殖與呼吸綜合症疫苗病毒
US20240189418A1 (en) * 2021-03-31 2024-06-13 The Industry & Academic Cooperation In Chungnam National University (Iac) Virus vaccine based on virus surface engineering providing increased immunity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101300363A (zh) * 2005-08-30 2008-11-05 内布拉斯加大学董事会 用于用具有改善的免疫原性的prrsv抗原免疫接种动物的方法和组合物
US20110104201A1 (en) * 1999-04-22 2011-05-05 Mengeling William L Porcine Reproductive and Respiratory Syndrome Vaccine Based on Isolate JA-142

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
KR100388257B1 (ko) 1997-05-06 2003-06-19 스티칭 디엔스트 랜드보위쿤디그 온데조에크 백신 또는 진단방법에서 사용하기 위한 피알알에스 바이러스의 피알알에스브이 항원부위 인식성 펩타이드 서열
US20020012670A1 (en) * 2000-01-26 2002-01-31 Knut Elbers Recombinant attenuation of porcine reproductive and respiratory syndrome (PRRSV)
AR027291A1 (es) * 2000-01-26 2003-03-19 Boehringer Ingelheim Vetmed Atenuacion recombinante de prrsv
CA2630648C (en) * 2005-11-29 2016-01-19 Iowa State University Research Foundation, Inc. Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus (prrsv) and uses thereof
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
US9187731B2 (en) * 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) * 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
EP2620446A1 (en) * 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
CN107635579A (zh) * 2014-03-21 2018-01-26 纽泰克温图斯公司 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110104201A1 (en) * 1999-04-22 2011-05-05 Mengeling William L Porcine Reproductive and Respiratory Syndrome Vaccine Based on Isolate JA-142
CN101300363A (zh) * 2005-08-30 2008-11-05 内布拉斯加大学董事会 用于用具有改善的免疫原性的prrsv抗原免疫接种动物的方法和组合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HIEP L. X. VU: "A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection", 《JOURNAL OF VIROLOGY》 *
TONG-QING AN等: "Identification of a Novel B Cell Epitope on the Nucleocapsid Protein of Porcine Reproductive and Respiratory Syndrome Virus by Phage Display", 《VIRUS GENES》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118791578A (zh) * 2024-07-29 2024-10-18 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 猪繁殖与呼吸综合征病毒nsp12蛋白的抗原表位、单克隆抗体及应用

Also Published As

Publication number Publication date
PH12020550204A1 (en) 2021-01-11
MX378873B (es) 2025-03-11
HK1247128A1 (zh) 2018-09-21
US20170198016A1 (en) 2017-07-13
PH12016501854A1 (en) 2017-01-09
US10072046B2 (en) 2018-09-11
CA2943478A1 (en) 2015-09-24
RU2016141287A (ru) 2018-04-26
RU2016141287A3 (https=) 2018-06-07
KR20170002393A (ko) 2017-01-06
PH12016501854B1 (en) 2017-01-09
US11136355B2 (en) 2021-10-05
EP3119429A4 (en) 2018-04-04
JP2017510276A (ja) 2017-04-13
US20200331970A1 (en) 2020-10-22
JP6538071B2 (ja) 2019-07-03
US10738088B2 (en) 2020-08-11
US20190048042A1 (en) 2019-02-14
RU2687150C2 (ru) 2019-05-07
WO2015140774A1 (en) 2015-09-24
EP3119429A1 (en) 2017-01-25
MX2016012276A (es) 2017-06-12

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