CA2933250A1 - Sgc stimulators - Google Patents
Sgc stimulators Download PDFInfo
- Publication number
- CA2933250A1 CA2933250A1 CA2933250A CA2933250A CA2933250A1 CA 2933250 A1 CA2933250 A1 CA 2933250A1 CA 2933250 A CA2933250 A CA 2933250A CA 2933250 A CA2933250 A CA 2933250A CA 2933250 A1 CA2933250 A1 CA 2933250A1
- Authority
- CA
- Canada
- Prior art keywords
- ring
- alkyl
- independently selected
- membered heteroaryl
- membered heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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Applications Claiming Priority (5)
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| US201361914908P | 2013-12-11 | 2013-12-11 | |
| US61/914,908 | 2013-12-11 | ||
| US201462051539P | 2014-09-17 | 2014-09-17 | |
| US62/051,539 | 2014-09-17 | ||
| PCT/US2014/069537 WO2015089182A1 (en) | 2013-12-11 | 2014-12-10 | Sgc stimulators |
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| CA2933250A1 true CA2933250A1 (en) | 2015-06-18 |
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| CA2933250A Abandoned CA2933250A1 (en) | 2013-12-11 | 2014-12-10 | Sgc stimulators |
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| US (2) | US20160311826A1 (https=) |
| EP (1) | EP3092231B1 (https=) |
| JP (1) | JP2016540017A (https=) |
| CN (1) | CN106304835A (https=) |
| CA (1) | CA2933250A1 (https=) |
| EA (1) | EA032028B1 (https=) |
| MX (1) | MX2016007522A (https=) |
| WO (1) | WO2015089182A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2588465B1 (en) | 2010-06-30 | 2017-01-25 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| EP2897953B8 (en) | 2012-09-19 | 2019-06-26 | Cyclerion Therapeutics, Inc. | Sgc stimulators |
| EA033168B1 (ru) | 2013-03-15 | 2019-09-30 | Сайклерион Терапьютикс, Инк. | СТИМУЛЯТОРЫ sGC |
| US20170298055A1 (en) * | 2014-09-17 | 2017-10-19 | Ironwood Pharmaceuticals, Inc. | sGC STIMULATORS |
| EP3194382B1 (en) * | 2014-09-17 | 2021-09-08 | Cyclerion Therapeutics, Inc. | Pyrazole derivatives as sgc stimulators |
| EP3194386A2 (en) * | 2014-09-17 | 2017-07-26 | Ironwood Pharmaceuticals, Inc. | Sgc stimulators |
| US20180344735A1 (en) | 2015-12-14 | 2018-12-06 | Ironwood Pharmaceuticals, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF GASTROINTESTINAL SPHINCTER DYSFUNCTION |
| CN109563077B (zh) | 2016-07-07 | 2026-03-10 | 赛克里翁治疗有限公司 | 用于制备可溶性鸟苷酸环化酶刺激剂的新方法 |
| SI3507291T1 (sl) | 2016-09-02 | 2021-11-30 | Cyclerion Therapeutics, Inc. | Kondenzirani biciklični SGS stimulatorji |
| CN109890379A (zh) | 2016-10-11 | 2019-06-14 | 拜耳制药股份公司 | 包含sGC活化剂和盐皮质激素受体拮抗剂的组合产品 |
| EP3525779B1 (de) | 2016-10-11 | 2024-06-05 | Bayer Pharma Aktiengesellschaft | Kombination enthaltend den sgc stimulator vericuguat und den mineralcorticoid-rezeptor-antagonist finerenone |
| EP3554488A2 (en) | 2016-12-13 | 2019-10-23 | Cyclerion Therapeutics, Inc. | Use of sgc stimulators for the treatment of esophageal motility disorders |
| CN108203396B (zh) * | 2016-12-19 | 2020-12-08 | 江西东邦药业有限公司 | 一种脑啡肽酶抑制剂的合成 |
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-
2014
- 2014-12-10 CA CA2933250A patent/CA2933250A1/en not_active Abandoned
- 2014-12-10 WO PCT/US2014/069537 patent/WO2015089182A1/en not_active Ceased
- 2014-12-10 CN CN201480074810.XA patent/CN106304835A/zh active Pending
- 2014-12-10 EP EP14824644.0A patent/EP3092231B1/en active Active
- 2014-12-10 EA EA201691194A patent/EA032028B1/ru not_active IP Right Cessation
- 2014-12-10 JP JP2016539132A patent/JP2016540017A/ja active Pending
- 2014-12-10 US US15/103,178 patent/US20160311826A1/en not_active Abandoned
- 2014-12-10 MX MX2016007522A patent/MX2016007522A/es unknown
-
2020
- 2020-12-15 US US17/122,542 patent/US20210214364A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015089182A1 (en) | 2015-06-18 |
| US20160311826A1 (en) | 2016-10-27 |
| EP3092231A1 (en) | 2016-11-16 |
| EP3092231B1 (en) | 2018-06-27 |
| EA032028B1 (ru) | 2019-03-29 |
| US20210214364A1 (en) | 2021-07-15 |
| JP2016540017A (ja) | 2016-12-22 |
| EA201691194A1 (ru) | 2016-12-30 |
| CN106304835A (zh) | 2017-01-04 |
| MX2016007522A (es) | 2017-12-15 |
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