CA2922192A1 - Halogenated compounds for cancer imaging and treatment and methods for their use - Google Patents
Halogenated compounds for cancer imaging and treatment and methods for their use Download PDFInfo
- Publication number
- CA2922192A1 CA2922192A1 CA2922192A CA2922192A CA2922192A1 CA 2922192 A1 CA2922192 A1 CA 2922192A1 CA 2922192 A CA2922192 A CA 2922192A CA 2922192 A CA2922192 A CA 2922192A CA 2922192 A1 CA2922192 A1 CA 2922192A1
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- Prior art keywords
- compound
- alkyl
- cancer
- acid
- prostate
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- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
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Applications Claiming Priority (3)
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| US201361875556P | 2013-09-09 | 2013-09-09 | |
| US61/875,556 | 2013-09-09 | ||
| PCT/CA2014/000685 WO2015031984A1 (en) | 2013-09-09 | 2014-09-09 | Halogenated compounds for cancer imaging and treatment and methods for their use |
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| CA2922192A1 true CA2922192A1 (en) | 2015-03-12 |
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| CA2922192A Abandoned CA2922192A1 (en) | 2013-09-09 | 2014-09-09 | Halogenated compounds for cancer imaging and treatment and methods for their use |
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| EP (1) | EP3044197B1 (enExample) |
| JP (1) | JP2016530285A (enExample) |
| KR (1) | KR20160054523A (enExample) |
| AU (1) | AU2014317753A1 (enExample) |
| CA (1) | CA2922192A1 (enExample) |
| SG (1) | SG11201601431VA (enExample) |
| WO (1) | WO2015031984A1 (enExample) |
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| KR20110044216A (ko) | 2008-07-02 | 2011-04-28 | 브리티쉬 콜롬비아 캔써 에이전시 브랜치 | 디글리시드 에테르 유도체 치료법 및 이의 사용 방법 |
| JP5940982B2 (ja) | 2010-01-06 | 2016-06-29 | ブリティッシュ コロンビア キャンサー エージェンシー ブランチ | アンドロゲンレセプター活性調節因子としての、ビスフェノール誘導体およびその使用 |
| US9365510B2 (en) | 2012-04-16 | 2016-06-14 | British Columbia Cancer Agency Branch | Aziridine bisphenol ethers and related compounds and methods for their use |
| PL3988541T3 (pl) | 2015-01-13 | 2024-12-16 | British Columbia Cancer Agency Branch | Związki heterocykliczne do obrazowania i leczenia nowotworów oraz sposoby ich zastosowania |
| US10471023B2 (en) | 2015-03-12 | 2019-11-12 | British Columbia Cancer Agency Branch | Bisphenol ether derivatives and methods for using the same |
| CA2929345A1 (en) * | 2015-09-02 | 2017-03-02 | British Columbia Cancer Agency Branch | Co-targeting androgen receptor splice variants and mtor signaling pathway for the treatment of castration-resistant prostate cancer |
| US20170298033A1 (en) | 2016-04-15 | 2017-10-19 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
| WO2017210771A1 (en) * | 2016-06-06 | 2017-12-14 | British Columbia Cancer Agency Branch | Compounds and compositions for radiation therapy and methods of using the same |
| US11485713B2 (en) | 2018-05-25 | 2022-11-01 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
| AU2019362061B2 (en) | 2018-10-18 | 2024-09-26 | Essa Pharma Inc | Androgen receptor modulators and methods for their use |
| WO2020198712A1 (en) | 2019-03-28 | 2020-10-01 | Essa Pharma, Inc. | Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof |
| US20210323931A1 (en) | 2020-04-17 | 2021-10-21 | Essa Pharma, Inc. | Solid forms of an n-terminal domain androgen receptor inhibitor and uses thereof |
| CA3192359A1 (en) | 2020-08-18 | 2022-02-24 | Enviro Metals, LLC | Metal refinement |
| WO2023046283A1 (en) | 2021-09-22 | 2023-03-30 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Compounds and their use in a method for modulating ar (androgen receptor) transcriptional activity |
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| KR20110044216A (ko) | 2008-07-02 | 2011-04-28 | 브리티쉬 콜롬비아 캔써 에이전시 브랜치 | 디글리시드 에테르 유도체 치료법 및 이의 사용 방법 |
| JP5940982B2 (ja) | 2010-01-06 | 2016-06-29 | ブリティッシュ コロンビア キャンサー エージェンシー ブランチ | アンドロゲンレセプター活性調節因子としての、ビスフェノール誘導体およびその使用 |
| US20130109758A1 (en) | 2010-01-06 | 2013-05-02 | The University Of British Columbia | Bisphenol derivative therapeutics and methods for their use |
| US20140248263A1 (en) | 2011-04-08 | 2014-09-04 | The University Of British Columbia | Bisphenol compounds and methods for their use |
| WO2012145330A1 (en) * | 2011-04-18 | 2012-10-26 | The University Of British Columbia | Fluorene-9-bisphenol compounds and methods for their use |
| WO2012145328A1 (en) | 2011-04-18 | 2012-10-26 | The University Of British Columbia | Dibenzylphenyl compounds and methods for their use |
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| WO2013028791A1 (en) | 2011-08-22 | 2013-02-28 | British Columbia Cancer Agency Branch | 18f compounds for cancer imaging and methods for their use |
| US9365510B2 (en) | 2012-04-16 | 2016-06-14 | British Columbia Cancer Agency Branch | Aziridine bisphenol ethers and related compounds and methods for their use |
| CA2911352A1 (en) | 2013-05-10 | 2014-11-13 | British Columbia Cancer Agency Branch | Ester derivatives of androgen receptor modulators and methods for their use |
| US20150010469A1 (en) | 2013-07-03 | 2015-01-08 | British Columbia Cancer Agency Branch | Bisphenol ether compounds with novel bridging groups and methods for their use |
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2014
- 2014-09-09 KR KR1020167008734A patent/KR20160054523A/ko not_active Withdrawn
- 2014-09-09 SG SG11201601431VA patent/SG11201601431VA/en unknown
- 2014-09-09 AU AU2014317753A patent/AU2014317753A1/en not_active Abandoned
- 2014-09-09 US US14/481,727 patent/US9375496B2/en active Active
- 2014-09-09 JP JP2016539372A patent/JP2016530285A/ja active Pending
- 2014-09-09 WO PCT/CA2014/000685 patent/WO2015031984A1/en not_active Ceased
- 2014-09-09 EP EP14843037.4A patent/EP3044197B1/en not_active Not-in-force
- 2014-09-09 CA CA2922192A patent/CA2922192A1/en not_active Abandoned
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2016
- 2016-05-17 US US15/157,075 patent/US20160367707A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015031984A1 (en) | 2015-03-12 |
| SG11201601431VA (en) | 2016-03-30 |
| EP3044197A4 (en) | 2017-04-05 |
| US20160367707A1 (en) | 2016-12-22 |
| AU2014317753A1 (en) | 2016-04-07 |
| JP2016530285A (ja) | 2016-09-29 |
| US20150125389A1 (en) | 2015-05-07 |
| US9375496B2 (en) | 2016-06-28 |
| EP3044197A1 (en) | 2016-07-20 |
| EP3044197B1 (en) | 2018-11-07 |
| KR20160054523A (ko) | 2016-05-16 |
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