CA2920346A1 - Preparation of (s,s)-secoisolariciresinol diglucoside and (r,r)-secoisolariciresinol diglucoside - Google Patents
Preparation of (s,s)-secoisolariciresinol diglucoside and (r,r)-secoisolariciresinol diglucoside Download PDFInfo
- Publication number
- CA2920346A1 CA2920346A1 CA2920346A CA2920346A CA2920346A1 CA 2920346 A1 CA2920346 A1 CA 2920346A1 CA 2920346 A CA2920346 A CA 2920346A CA 2920346 A CA2920346 A CA 2920346A CA 2920346 A1 CA2920346 A1 CA 2920346A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- formula
- reacting
- prepare
- carried out
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361833258P | 2013-06-10 | 2013-06-10 | |
| US61/833,258 | 2013-06-10 | ||
| PCT/US2014/041636 WO2014200964A1 (en) | 2013-06-10 | 2014-06-10 | Preparation of (s,s)-secoisolariciresinol diglucoside and (r,r)-secoisolariciresinol diglucoside |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2920346A1 true CA2920346A1 (en) | 2014-12-18 |
Family
ID=52022698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2920346A Abandoned CA2920346A1 (en) | 2013-06-10 | 2014-06-10 | Preparation of (s,s)-secoisolariciresinol diglucoside and (r,r)-secoisolariciresinol diglucoside |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US10030040B2 (https=) |
| EP (2) | EP3488697A1 (https=) |
| JP (3) | JP6321788B2 (https=) |
| KR (1) | KR102270124B1 (https=) |
| CN (2) | CN107955046A (https=) |
| AU (1) | AU2014278362B2 (https=) |
| CA (1) | CA2920346A1 (https=) |
| CY (1) | CY1120759T1 (https=) |
| DK (1) | DK3007557T3 (https=) |
| ES (1) | ES2691845T3 (https=) |
| HR (1) | HRP20181663T1 (https=) |
| HU (1) | HUE040022T2 (https=) |
| IL (2) | IL243029B (https=) |
| LT (1) | LT3007557T (https=) |
| PL (1) | PL3007557T3 (https=) |
| PT (1) | PT3007557T (https=) |
| RS (1) | RS57846B1 (https=) |
| SI (1) | SI3007557T1 (https=) |
| SM (1) | SMT201800575T1 (https=) |
| TR (1) | TR201815423T4 (https=) |
| WO (1) | WO2014200964A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS57846B1 (sr) | 2013-06-10 | 2018-12-31 | Univ Pennsylvania | Dobijanje (s,s)-sekoizolaricirezinol diglukozida i (r,r)-sekoizolaricirezinol diglukozida |
| AU2015266614A1 (en) * | 2014-05-30 | 2016-12-15 | The Trustees Of The University Of Pennsylvania | Use of secoisolariciresinol diglucosides (SDGs) and related compounds for protection against radiation and chemical damage |
| US11197876B2 (en) | 2014-05-30 | 2021-12-14 | The Trusiees Of The University Of Pennsylvania | Effects of LGM2605 on a primate model of asthma |
| US20170258821A1 (en) | 2014-05-30 | 2017-09-14 | The Trustees Of The University Of Pennsylvania | USE OF SECOISOLARICIRESINOL DIGLUCOSIDES (SDGs) AND RELATED COMPOUNDS FOR PROTECTION AGAINST RADIATION AND CHEMICAL DAMAGE |
| AU2016315952A1 (en) * | 2015-09-01 | 2018-04-05 | The Trustees Of The University Of Pennsylvania | Use of secoisolariciresinol diglucosides (SDGs) and related compounds for protection against radiation damage |
| ES2969209T3 (es) | 2016-06-07 | 2024-05-17 | Univ Pennsylvania | Composiciones y métodos para proteger órganos de lesiones por isquemia/reperfusión asociadas con el trasplante |
| JP2020523394A (ja) | 2017-06-12 | 2020-08-06 | リグナメッド・エルエルシーＬｉｇｎａｍｅｄ，Ｌｌｃ | （ｓ，ｓ）−セコイソラリシレシノールジグルコシド及び（ｒ，ｒ）−セコイソラリシレシノールジグルコシドの製造方法 |
| CN110283218A (zh) * | 2019-06-24 | 2019-09-27 | 暨南大学 | 提高木酚素油溶性的改性方法 |
| CN111233944B (zh) * | 2020-03-25 | 2023-02-28 | 宝鸡市辰光生物科技有限公司 | 一种同时制备分离四种木脂素类成分的高效液相方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3065925B2 (ja) * | 1996-01-30 | 2000-07-17 | 日清製油株式会社 | 活性酸素種消去剤及び退色防止剤 |
| AU3760699A (en) * | 1998-04-24 | 1999-11-16 | Washington State University Research Foundation | Recombinant secoisolariciresinol dehydrogenase, and methods of use |
| FI110868B (fi) | 2001-01-22 | 2003-04-15 | Maa Ja Elintarviketalouden Tut | Menetelmä sekoisolarisiresinolidiglykosidin (SDG) eristämiseksi ja puhdistamiseksi pellavansiemenistä |
| US20030060420A1 (en) | 2001-09-14 | 2003-03-27 | Rick Heintzman | Process for extraction and stabilization of phytoestrogens from flaxseed and product therefrom |
| DE60333353D1 (de) | 2002-04-02 | 2010-08-26 | Lignan Res Llc | Verfahren zur wiedergewinnung von secoisolariciresinol diglycosid aus entfetteten flachs-saatgut |
| JP2006347978A (ja) * | 2005-06-17 | 2006-12-28 | Nippon Flour Mills Co Ltd | 抗肥満剤及びこれを含む食品並びにペットフード |
| JP2007308469A (ja) * | 2005-11-11 | 2007-11-29 | Nippon Flour Mills Co Ltd | リグナンを有効成分とする男性用抗肥満剤 |
| CN100395253C (zh) * | 2006-05-12 | 2008-06-18 | 中国科学院山西煤炭化学研究所 | 一种由亚麻籽制备开环异落叶松树脂酚二葡萄糖苷的方法 |
| CN101117641B (zh) * | 2007-07-27 | 2011-05-11 | 大连医诺生物有限公司 | 开环异落叶松树脂酚二葡萄糖苷的制备方法 |
| JP2010057367A (ja) | 2008-09-01 | 2010-03-18 | Nitto Boseki Co Ltd | 魚肉の褐変防止剤および褐変防止方法 |
| CN102050848A (zh) * | 2009-11-01 | 2011-05-11 | 桂林莱茵生物科技股份有限公司 | 一种亚麻木酚素的制备方法 |
| ES2362065B1 (es) * | 2009-12-15 | 2012-05-18 | Consejo Superior De Investigaciones Cient�?Ficas (Csic) | Compuestos con actividad antiinflamatoria. |
| WO2012021983A1 (en) * | 2010-08-20 | 2012-02-23 | Fédération Des Producteurs Acéricoles Du Québec | Sugar plant derived by-products and methods of production thereof |
| CN102558252A (zh) | 2010-12-31 | 2012-07-11 | 西安天一生物技术有限公司 | 一种亚麻木酚素的生产工艺 |
| RS57846B1 (sr) * | 2013-06-10 | 2018-12-31 | Univ Pennsylvania | Dobijanje (s,s)-sekoizolaricirezinol diglukozida i (r,r)-sekoizolaricirezinol diglukozida |
-
2014
- 2014-06-10 RS RS20181236A patent/RS57846B1/sr unknown
- 2014-06-10 DK DK14811683.3T patent/DK3007557T3/en active
- 2014-06-10 CN CN201711326022.7A patent/CN107955046A/zh active Pending
- 2014-06-10 CN CN201480041131.2A patent/CN105705018B/zh active Active
- 2014-06-10 ES ES14811683.3T patent/ES2691845T3/es active Active
- 2014-06-10 EP EP18183923.4A patent/EP3488697A1/en not_active Withdrawn
- 2014-06-10 LT LTEP14811683.3T patent/LT3007557T/lt unknown
- 2014-06-10 PT PT14811683T patent/PT3007557T/pt unknown
- 2014-06-10 HR HRP20181663TT patent/HRP20181663T1/hr unknown
- 2014-06-10 KR KR1020167000483A patent/KR102270124B1/ko active Active
- 2014-06-10 JP JP2016519582A patent/JP6321788B2/ja not_active Expired - Fee Related
- 2014-06-10 SI SI201430924T patent/SI3007557T1/sl unknown
- 2014-06-10 TR TR2018/15423T patent/TR201815423T4/tr unknown
- 2014-06-10 HU HUE14811683A patent/HUE040022T2/hu unknown
- 2014-06-10 AU AU2014278362A patent/AU2014278362B2/en not_active Ceased
- 2014-06-10 EP EP14811683.3A patent/EP3007557B1/en active Active
- 2014-06-10 US US14/897,181 patent/US10030040B2/en active Active
- 2014-06-10 WO PCT/US2014/041636 patent/WO2014200964A1/en not_active Ceased
- 2014-06-10 PL PL14811683T patent/PL3007557T3/pl unknown
- 2014-06-10 CA CA2920346A patent/CA2920346A1/en not_active Abandoned
- 2014-06-10 SM SM20180575T patent/SMT201800575T1/it unknown
-
2015
- 2015-12-10 IL IL243029A patent/IL243029B/en active IP Right Grant
-
2018
- 2018-04-04 JP JP2018072178A patent/JP6513853B2/ja not_active Expired - Fee Related
- 2018-07-23 US US16/042,866 patent/US10870670B2/en active Active
- 2018-10-16 CY CY181101054T patent/CY1120759T1/el unknown
-
2019
- 2019-04-10 JP JP2019074548A patent/JP6785335B2/ja active Active
- 2019-09-24 IL IL26962219A patent/IL269622A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190516 |
|
| FZDE | Discontinued |
Effective date: 20230411 |