CA2910427C - Delivery methods and compositions for nuclease-mediated genome engineering - Google Patents
Delivery methods and compositions for nuclease-mediated genome engineering Download PDFInfo
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- CA2910427C CA2910427C CA2910427A CA2910427A CA2910427C CA 2910427 C CA2910427 C CA 2910427C CA 2910427 A CA2910427 A CA 2910427A CA 2910427 A CA2910427 A CA 2910427A CA 2910427 C CA2910427 C CA 2910427C
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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| PCT/US2014/036972 WO2014182700A1 (en) | 2013-05-10 | 2014-05-06 | Delivery methods and compositions for nuclease-mediated genome engineering |
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- 2014-05-06 CA CA2910427A patent/CA2910427C/en active Active
- 2014-05-06 JP JP2016513016A patent/JP2016518142A/ja active Pending
- 2014-05-06 WO PCT/US2014/036972 patent/WO2014182700A1/en not_active Ceased
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| JP2016518142A (ja) | 2016-06-23 |
| EP2994531B1 (en) | 2018-03-28 |
| EP2994531A4 (en) | 2016-11-23 |
| AU2014262867A1 (en) | 2015-11-12 |
| CA2910427A1 (en) | 2014-11-13 |
| AU2014262867B2 (en) | 2019-12-05 |
| WO2014182700A1 (en) | 2014-11-13 |
| EP2994531A1 (en) | 2016-03-16 |
| US10604771B2 (en) | 2020-03-31 |
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