CA2905564A1 - A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids - Google Patents

A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids Download PDF

Info

Publication number
CA2905564A1
CA2905564A1 CA2905564A CA2905564A CA2905564A1 CA 2905564 A1 CA2905564 A1 CA 2905564A1 CA 2905564 A CA2905564 A CA 2905564A CA 2905564 A CA2905564 A CA 2905564A CA 2905564 A1 CA2905564 A1 CA 2905564A1
Authority
CA
Canada
Prior art keywords
electromagnetic radiation
objects
measuring apparatus
microscopic
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2905564A
Other languages
English (en)
French (fr)
Inventor
Richard Harry Turner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2905564A1 publication Critical patent/CA2905564A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/06Means for illuminating specimens
    • G02B21/08Condensers
    • G02B21/088Condensers for both incident illumination and transillumination
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/30Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/70Determining position or orientation of objects or cameras
    • G06T7/73Determining position or orientation of objects or cameras using feature-based methods
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/168Specific optical properties, e.g. reflective coatings
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10141Special mode during image acquisition
    • G06T2207/10152Varying illumination
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30024Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Optics & Photonics (AREA)
  • Quality & Reliability (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Microscoopes, Condenser (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Image Processing (AREA)
  • Sampling And Sample Adjustment (AREA)
CA2905564A 2013-03-15 2014-03-10 A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids Abandoned CA2905564A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361790764P 2013-03-15 2013-03-15
US61/790,764 2013-03-15
PCT/IB2014/059581 WO2014141034A2 (en) 2013-03-15 2014-03-10 A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids

Publications (1)

Publication Number Publication Date
CA2905564A1 true CA2905564A1 (en) 2014-09-18

Family

ID=51538221

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2905564A Abandoned CA2905564A1 (en) 2013-03-15 2014-03-10 A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids

Country Status (10)

Country Link
US (1) US10032270B2 (cg-RX-API-DMAC7.html)
EP (1) EP2973408A4 (cg-RX-API-DMAC7.html)
JP (1) JP2016522880A (cg-RX-API-DMAC7.html)
CN (1) CN105492887A (cg-RX-API-DMAC7.html)
AU (1) AU2014229420A1 (cg-RX-API-DMAC7.html)
BR (1) BR112015023081A2 (cg-RX-API-DMAC7.html)
CA (1) CA2905564A1 (cg-RX-API-DMAC7.html)
EA (1) EA201591800A1 (cg-RX-API-DMAC7.html)
SG (2) SG11201506786VA (cg-RX-API-DMAC7.html)
WO (1) WO2014141034A2 (cg-RX-API-DMAC7.html)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3955042B1 (en) 2013-08-26 2024-08-21 S.D. Sight Diagnostics Ltd. Digital microscopy systems, methods and computer program products
JP6537332B2 (ja) * 2014-04-28 2019-07-03 キヤノン株式会社 画像処理方法および撮影装置
KR20180016391A (ko) * 2015-05-08 2018-02-14 플로우조, 엘엘시 데이터 발견 노드
EP3859425B1 (en) 2015-09-17 2024-04-17 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
JP6887599B2 (ja) * 2015-10-14 2021-06-16 ホリバ インスツルメンツ インコーポレイテッドHoriba Instruments Incorporated コロイド粒子の成長キネティクスまたは分解キネティクスの測定のための装置および方法
JP2017142118A (ja) * 2016-02-09 2017-08-17 株式会社イシダ 光検査装置
US11733150B2 (en) 2016-03-30 2023-08-22 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
KR102497849B1 (ko) 2016-05-09 2023-02-07 삼성전자주식회사 분석물질 농도 예측 방법 및 장치
BR112018072627A2 (pt) 2016-05-11 2019-02-19 S D Sight Diagnostics Ltd realização de medições óticas em uma amostra
EP4177593A1 (en) 2016-05-11 2023-05-10 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
EP3279635B1 (en) * 2016-08-04 2022-06-01 Malvern Panalytical Limited Method, processor and machine-readable, non-transient storage medium for characterising particles suspended in a fluid dispersant
KR102231664B1 (ko) * 2016-12-02 2021-03-23 몰레큘러 임프린츠 인코퍼레이티드 임프린트 리소그래피 공정들에서 광학 층들을 구성하는 방법
EP3606412A4 (en) * 2017-04-07 2020-12-23 Toi Labs, Inc. BIOSURVEILLANCE DEVICES, METHODS AND SYSTEMS FOR USE IN A BATHROOM LAYOUT
US12440193B2 (en) 2017-04-07 2025-10-14 Toi Labs, Inc. System, method and apparatus for forming machine learning sessions
JP6959755B2 (ja) 2017-04-14 2021-11-05 シスメックス株式会社 蛍光画像分析装置、蛍光画像の分析方法及びコンピュータプログラム
CN107290291A (zh) * 2017-07-02 2017-10-24 广东技术师范学院 双光程调制透射和荧光激发光源测量复杂溶液成分的方法
JP7007122B2 (ja) 2017-07-11 2022-01-24 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
JP2021501322A (ja) * 2017-10-26 2021-01-14 エッセンリックス コーポレーション 血小板の高速測定法
FR3073047B1 (fr) * 2017-11-02 2021-01-29 Commissariat Energie Atomique Procede optique d'estimation d'un volume representatif de particules presentes dans un echantillon
US11921272B2 (en) 2017-11-14 2024-03-05 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
AU2018385767A1 (en) 2017-12-15 2020-06-11 Gastroklenz Inc. Sensor monitoring system for in-dwelling catheter based treatments
CN109001191A (zh) * 2018-06-06 2018-12-14 西安纸贵互联网科技有限公司 一种体外诊断试剂的半定量识别方法及装置
CN109235585A (zh) * 2018-09-19 2019-01-18 浙江瑞宝生物科技有限公司 马桶内藏排泄物潜血检测装置及其方法
US11154863B2 (en) * 2018-10-08 2021-10-26 Bioelectronica Corporation Systems and methods for optically processing samples
CN111077073A (zh) * 2018-10-19 2020-04-28 深圳迈瑞生物医疗电子股份有限公司 一种样本分析仪
CN113167718A (zh) * 2018-10-22 2021-07-23 生物电子公司 多路复用的测定系统和方法
JP7376245B2 (ja) 2019-03-29 2023-11-08 シスメックス株式会社 蛍光画像分析装置及び蛍光画像分析方法
MX2021016013A (es) 2019-06-26 2022-03-11 Gastroklenz Inc Sistemas, dispositivos, y metodos para el monitoreo de fluidos.
USD984637S1 (en) 2019-06-26 2023-04-25 Gastroklenz Inc. Measurement vessel
USD903126S1 (en) 2019-06-26 2020-11-24 Gastroklenz Inc. Monitoring device
CN110426335B (zh) * 2019-09-05 2022-03-22 苏州大学 一种基于原子力显微镜的纳米颗粒浓度测量方法
AU2020370212B2 (en) 2019-10-22 2025-09-25 S.D. Sight Diagnostics Ltd Accounting for errors in optical measurements
WO2021116962A1 (en) 2019-12-12 2021-06-17 S.D. Sight Diagnostics Ltd Artificial generation of color blood smear image
EP4073492A1 (en) 2019-12-12 2022-10-19 S.D. Sight Diagnostics Ltd. Analyzing an analyte disposed within a medium
CN110940621B (zh) * 2019-12-19 2020-09-15 西安交通大学 一种基于红外技术的凝结液珠形态的识别方法
US10823662B1 (en) * 2020-02-18 2020-11-03 Horiba Instruments, Incorporated Special purpose cuvette assembly and method for optical microscopy of nanoparticle colloids
EP3933479A1 (en) * 2020-07-03 2022-01-05 Leica Microsystems CMS GmbH Microscope for microscopic examination of a sample
CN113340894B (zh) * 2021-05-28 2023-04-07 上海睿钰生物科技有限公司 一种非透明微粒的检测方法
CN119968567A (zh) 2022-10-14 2025-05-09 爱科来株式会社 信息处理装置、信息处理方法和信息处理程序

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4592089A (en) 1983-08-15 1986-05-27 Bio Image Corporation Electrophoretogram analytical image processing system
US4998284A (en) 1987-11-17 1991-03-05 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
US5134662A (en) 1985-11-04 1992-07-28 Cell Analysis Systems, Inc. Dual color camera microscope and methodology for cell staining and analysis
US4965725B1 (en) * 1988-04-08 1996-05-07 Neuromedical Systems Inc Neural network based automated cytological specimen classification system and method
ATE174813T1 (de) 1992-05-01 1999-01-15 Univ Pennsylvania Polynukleotide amplifikationsanalyse mit einer mikrofabrizierten vorrichtung
US5889881A (en) * 1992-10-14 1999-03-30 Oncometrics Imaging Corp. Method and apparatus for automatically detecting malignancy-associated changes
WO2001094528A2 (en) 2000-06-08 2001-12-13 The Regents Of The University Of California Visual-servoing optical microscopy
EP1301118B1 (en) * 2000-07-14 2006-09-06 Xillix Technologies Corp. Compact fluorescence endoscopy video system
US6993169B2 (en) * 2001-01-11 2006-01-31 Trestle Corporation System and method for finding regions of interest for microscopic digital montage imaging
JP2003075725A (ja) 2001-09-04 2003-03-12 Olympus Optical Co Ltd 透過照明装置
JP2006516920A (ja) * 2003-02-06 2006-07-13 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 血液分析のための装置及び方法
CA3074799C (en) * 2003-03-28 2022-12-06 Inguran, Llc Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm
DE102005052752A1 (de) 2005-11-04 2007-05-10 Clondiag Chip Technologies Gmbh Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen
US7307802B2 (en) * 2004-06-07 2007-12-11 Fluidigm Corporation Optical lens system and method for microfluidic devices
US20060066850A1 (en) 2004-09-29 2006-03-30 Fuji Photo Film Co., Ltd. Light measuring device, biochemical analyzer, biochemical analysis method, and spectrophotometer
JP2006098227A (ja) 2004-09-29 2006-04-13 Fuji Photo Film Co Ltd 反射光測定装置及び生化学分析装置
JP2006238802A (ja) * 2005-03-03 2006-09-14 Olympus Corp 細胞観察装置、細胞観察方法、顕微鏡システム、及び細胞観察プログラム
CA2607284A1 (en) 2005-05-11 2006-11-23 Embrex, Inc. Competitive particle immunoassay methods utilizing fluorescence microscopy
TWI330380B (en) * 2006-12-07 2010-09-11 Nat Univ Tsing Hua A specimen kit for electron microscope and its fabrication process
CA2580589C (en) * 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
US7738094B2 (en) 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
TWI320856B (en) * 2007-03-26 2010-02-21 Asia Optical Co Inc Optical apparatus with dual illuminating devices
US9925536B2 (en) 2007-07-23 2018-03-27 Clondiag Gmbh Assays for measuring nucleic acids
AT508102A1 (de) 2009-04-08 2010-10-15 Photonic Optische Geraete Gmbh Beleuchtungseinrichtung
US8570370B2 (en) * 2009-08-31 2013-10-29 Bio-Rad Laboratories, Inc. Compact automated cell counter
FR2951542B1 (fr) * 2009-10-16 2011-12-02 Commissariat Energie Atomique Procede de detection optique d'objets micrometriques en solution
US8603804B2 (en) 2010-01-15 2013-12-10 Qbc Diagnostics, Inc. Fluorescent marked microscope slide
WO2011119678A2 (en) * 2010-03-23 2011-09-29 California Institute Of Technology Super resolution optofluidic microscopes for 2d and 3d imaging
WO2011144212A1 (en) 2010-05-21 2011-11-24 Chemometec A/S A compact dark field light source and dark field image analysis at low magnification
JP5703609B2 (ja) 2010-07-02 2015-04-22 ソニー株式会社 顕微鏡及び領域判定方法
WO2012058233A2 (en) * 2010-10-26 2012-05-03 California Institute Of Technology Scanning projective lensless microscope system
WO2014078402A1 (en) * 2012-11-16 2014-05-22 Protochips, Inc. A method for forming an electrical connection to a sample support in an electron microscope holder
WO2014143155A1 (en) * 2013-03-12 2014-09-18 Ventana Medical Systems, Inc. Digitally enhanced microscopy for multiplexed histology

Also Published As

Publication number Publication date
CN105492887A (zh) 2016-04-13
BR112015023081A2 (pt) 2017-07-18
JP2016522880A (ja) 2016-08-04
US20160042507A1 (en) 2016-02-11
US10032270B2 (en) 2018-07-24
EA201591800A1 (ru) 2016-04-29
WO2014141034A3 (en) 2015-12-17
SG10201707599WA (en) 2017-10-30
SG11201506786VA (en) 2015-09-29
EP2973408A2 (en) 2016-01-20
EP2973408A4 (en) 2017-06-14
AU2014229420A1 (en) 2015-09-24
WO2014141034A2 (en) 2014-09-18

Similar Documents

Publication Publication Date Title
US10032270B2 (en) System and methods for the in vitro detection of particles and soluble chemical entities in body fluids
JP7672399B2 (ja) 光学測定におけるエラーの原因の説明
JP5184697B2 (ja) 血小板を個々に、及び凝集塊として検出及び計数するための方法及び装置
EP3279657B1 (en) Urinalysis system and urinalysis method
JP2022078344A (ja) 生物学的サンプルの画像分析および測定
JP5671517B2 (ja) 蛍光消光及び/又は蛍光退色を用いて個々の細胞又は粒状物質を分析するための方法及び装置
CN1181343C (zh) 用于对尿样进行化学、定性、定量和半定量分析的方法和装置
CN105228749B (zh) 便携式血细胞计数监测器
CN101852715B (zh) 尿样分析仪
US20130280698A1 (en) Rapid multiplex lateral flow assay device
JP5351585B2 (ja) 腎疾患診断支援装置およびコンピュータプログラム
JP6974426B2 (ja) 生体試料分析システム、構成要素、およびその方法
JP2015501929A (ja) 試験システム構成および試験の方法
RU2803847C1 (ru) Учет ошибок при оптических измерениях
RU2797528C1 (ru) Учет ошибок при оптических измерениях
EP3798614B1 (en) Modular multiplex analysis devices and platforms

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20190312