CA2904353A1 - Methods of treating renal disease and other disorders - Google Patents

Methods of treating renal disease and other disorders Download PDF

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Publication number
CA2904353A1
CA2904353A1 CA2904353A CA2904353A CA2904353A1 CA 2904353 A1 CA2904353 A1 CA 2904353A1 CA 2904353 A CA2904353 A CA 2904353A CA 2904353 A CA2904353 A CA 2904353A CA 2904353 A1 CA2904353 A1 CA 2904353A1
Authority
CA
Canada
Prior art keywords
patient
administering
effective amount
metap2 inhibitor
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2904353A
Other languages
English (en)
French (fr)
Inventor
Thomas E. Hughes
James E. Vath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Larimar Therapeutics Inc
Original Assignee
Zafgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zafgen Inc filed Critical Zafgen Inc
Publication of CA2904353A1 publication Critical patent/CA2904353A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nutrition Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
CA2904353A 2013-03-14 2014-03-14 Methods of treating renal disease and other disorders Abandoned CA2904353A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361781926P 2013-03-14 2013-03-14
US61/781,926 2013-03-14
US201361787769P 2013-03-15 2013-03-15
US61/787,769 2013-03-15
PCT/US2014/028022 WO2014152861A2 (en) 2013-03-14 2014-03-14 Methods of treating renal disease and other disorders

Publications (1)

Publication Number Publication Date
CA2904353A1 true CA2904353A1 (en) 2014-09-25

Family

ID=50736155

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2904353A Abandoned CA2904353A1 (en) 2013-03-14 2014-03-14 Methods of treating renal disease and other disorders

Country Status (10)

Country Link
US (3) US9597309B2 (enExample)
EP (1) EP2968250B1 (enExample)
JP (2) JP2016513722A (enExample)
KR (1) KR20150126924A (enExample)
CN (1) CN105228610A (enExample)
AU (2) AU2014236528A1 (enExample)
BR (1) BR112015023390A2 (enExample)
CA (1) CA2904353A1 (enExample)
MX (1) MX362391B (enExample)
WO (1) WO2014152861A2 (enExample)

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* Cited by examiner, † Cited by third party
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AR105671A1 (es) 2015-08-11 2017-10-25 Zafgen Inc Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso

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Also Published As

Publication number Publication date
AU2014236528A1 (en) 2015-09-24
EP2968250A2 (en) 2016-01-20
US20160038453A1 (en) 2016-02-11
AU2018282489A1 (en) 2019-01-24
US20170333383A1 (en) 2017-11-23
JP2016513722A (ja) 2016-05-16
US10231946B2 (en) 2019-03-19
EP2968250B1 (en) 2019-06-19
US9849106B2 (en) 2017-12-26
JP2019019146A (ja) 2019-02-07
BR112015023390A2 (pt) 2017-07-18
MX362391B (es) 2019-01-15
MX2015012164A (es) 2016-05-16
WO2014152861A3 (en) 2014-11-20
US20180085338A1 (en) 2018-03-29
US9597309B2 (en) 2017-03-21
WO2014152861A2 (en) 2014-09-25
CN105228610A (zh) 2016-01-06
KR20150126924A (ko) 2015-11-13

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