CA2899737A1 - Factor viii polypeptide formulations - Google Patents

Factor viii polypeptide formulations Download PDF

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Publication number
CA2899737A1
CA2899737A1 CA2899737A CA2899737A CA2899737A1 CA 2899737 A1 CA2899737 A1 CA 2899737A1 CA 2899737 A CA2899737 A CA 2899737A CA 2899737 A CA2899737 A CA 2899737A CA 2899737 A1 CA2899737 A1 CA 2899737A1
Authority
CA
Canada
Prior art keywords
pharmaceutical composition
polysorbate
fviii polypeptide
polypeptide
fviii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2899737A
Other languages
English (en)
French (fr)
Inventor
Kevin Maloney
Ahmad ABDUL-FATTAH
Daniel GAGE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioverativ Therapeutics Inc
Original Assignee
Biogen MA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50771579&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2899737(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen MA Inc filed Critical Biogen MA Inc
Publication of CA2899737A1 publication Critical patent/CA2899737A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2899737A 2013-03-15 2014-03-14 Factor viii polypeptide formulations Pending CA2899737A1 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201361800293P 2013-03-15 2013-03-15
US61/800,293 2013-03-15
US201361817085P 2013-04-29 2013-04-29
US61/817,085 2013-04-29
US201361829884P 2013-05-31 2013-05-31
US61/829,884 2013-05-31
US201361839477P 2013-06-26 2013-06-26
US61/839,477 2013-06-26
US201361863860P 2013-08-08 2013-08-08
US61/863,860 2013-08-08
US201361876927P 2013-09-12 2013-09-12
US61/876,927 2013-09-12
US201361879955P 2013-09-19 2013-09-19
US61/879,955 2013-09-19
US201361897742P 2013-10-30 2013-10-30
US61/897,742 2013-10-30
PCT/US2014/029354 WO2014144795A1 (en) 2013-03-15 2014-03-14 Factor viii polypeptide formulations

Publications (1)

Publication Number Publication Date
CA2899737A1 true CA2899737A1 (en) 2014-09-18

Family

ID=50771579

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2899737A Pending CA2899737A1 (en) 2013-03-15 2014-03-14 Factor viii polypeptide formulations

Country Status (20)

Country Link
US (3) US9623088B2 (https=)
EP (3) EP4122487A1 (https=)
JP (5) JP6330026B2 (https=)
AU (4) AU2014228506A1 (https=)
CA (1) CA2899737A1 (https=)
CL (1) CL2015002720A1 (https=)
DK (1) DK2968477T3 (https=)
EA (2) EA030357B1 (https=)
ES (2) ES2776195T3 (https=)
HU (1) HUE047933T2 (https=)
LT (1) LT2968477T (https=)
PH (2) PH12015501801B1 (https=)
PL (2) PL3666283T3 (https=)
PT (2) PT3666283T (https=)
RS (1) RS60003B1 (https=)
SG (2) SG10201805207QA (https=)
SI (1) SI2968477T1 (https=)
TW (2) TWI629993B (https=)
UY (1) UY35462A (https=)
WO (1) WO2014144795A1 (https=)

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PL3326643T3 (pl) * 2009-12-06 2021-10-25 Bioverativ Therapeutics Inc. Chimeryczne i hybrydowe polipeptydy czynnika VIII-FC oraz sposoby ich zastosowania
AR095527A1 (es) 2013-03-15 2015-10-21 Biogen Idec Inc Formulaciones de polipéptido fc-factor ix
DK2968477T3 (da) 2013-03-15 2020-03-09 Bioverativ Therapeutics Inc Faktor viii-polypeptidformuleringer
CN107759697B (zh) 2016-08-19 2023-03-24 安源医药科技（上海）有限公司 制备融合蛋白的方法
CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
IL319473A (en) 2016-12-02 2025-05-01 Bioverativ Therapeutics Inc Methods for treating hemophilic arthritis using chimeric blood clotting factors
CN110520149A (zh) 2016-12-02 2019-11-29 比奥维拉迪维治疗股份有限公司 诱导对凝血因子的免疫耐受性的方法
JP7039308B2 (ja) * 2017-02-08 2022-03-22 三洋化成工業株式会社 細胞培養用担体
TW202545984A (zh) 2017-08-09 2025-12-01 美商生物化學醫療公司 核酸分子及其用途
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WO2020033863A1 (en) 2018-08-09 2020-02-13 Bioverativ Therapeutics Inc. Nucleic acid molecules and uses thereof for non-viral gene therapy
US12252528B2 (en) * 2018-10-23 2025-03-18 The Children's Hospital Of Philadelphia Compositions and methods for modulating Factor VIII function
JP7501875B2 (ja) * 2019-02-28 2024-06-18 公立大学法人横浜市立大学 血液凝固および／または補体異常疾患の治療用組成物
BR112021020668A2 (pt) 2019-04-17 2022-01-11 Codiak Biosciences Inc Composições de exossomos e aav
US20220233650A1 (en) * 2019-06-19 2022-07-28 Bioverativ Therapeutics Inc. Recombinant factor viii-fc for treating hemophilia and low bone mineral density
TW202400238A (zh) * 2022-05-10 2024-01-01 南韓商綠十字股份有限公司 血漿蛋白之新穎液體調配物
KR20230159285A (ko) * 2022-05-10 2023-11-21 주식회사 녹십자 혈장 단백질의 동결 건조를 위한 신규한 액상 제형물

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Also Published As

Publication number Publication date
JP2023060146A (ja) 2023-04-27
SI2968477T1 (sl) 2020-04-30
US20170281734A1 (en) 2017-10-05
CL2015002720A1 (es) 2016-11-04
JP6330026B2 (ja) 2018-05-23
PH12015501801A1 (en) 2015-11-09
TW201501722A (zh) 2015-01-16
SG10201805207QA (en) 2018-07-30
JP7240457B2 (ja) 2023-03-15
PT3666283T (pt) 2022-09-13
PH12015501801B1 (en) 2019-11-20
JP6934994B2 (ja) 2021-09-15
AU2025204069A9 (en) 2026-03-19
US20140308280A1 (en) 2014-10-16
EP2968477B1 (en) 2019-12-04
DK2968477T3 (da) 2020-03-09
US12403183B2 (en) 2025-09-02
US9623088B2 (en) 2017-04-18
EA201591439A1 (ru) 2016-03-31
AU2021277601A1 (en) 2021-12-23
JP7700164B2 (ja) 2025-06-30
RS60003B1 (sr) 2020-04-30
HK1220617A1 (en) 2017-05-12
AU2021277601B2 (en) 2025-03-06
ES2926798T3 (es) 2022-10-28
TW201842930A (zh) 2018-12-16
SG11201505924TA (en) 2015-09-29
TWI629993B (zh) 2018-07-21
EP2968477A1 (en) 2016-01-20
TWI690325B (zh) 2020-04-11
PH12019502452A1 (en) 2021-02-08
EA030357B1 (ru) 2018-07-31
AU2025204069A1 (en) 2025-06-26
WO2014144795A1 (en) 2014-09-18
EA201890671A1 (ru) 2019-01-31
EP3666283B1 (en) 2022-06-08
AU2019202656A1 (en) 2019-05-09
AU2019202656B2 (en) 2021-09-02
PL2968477T3 (pl) 2020-06-15
EP3666283A1 (en) 2020-06-17
ES2776195T3 (es) 2020-07-29
JP2020186268A (ja) 2020-11-19
AU2014228506A1 (en) 2015-08-13
JP2016516722A (ja) 2016-06-09
LT2968477T (lt) 2020-03-10
UY35462A (es) 2014-10-31
US20210069300A1 (en) 2021-03-11
PT2968477T (pt) 2020-03-11
HUE047933T2 (hu) 2020-05-28
JP2018123161A (ja) 2018-08-09
EP4122487A1 (en) 2023-01-25
US10786554B2 (en) 2020-09-29
PL3666283T3 (pl) 2022-10-03
JP2021181491A (ja) 2021-11-25

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