CA2883002C - Compositions comprising mixtures of semifluorinated alkanes - Google Patents

Compositions comprising mixtures of semifluorinated alkanes Download PDF

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Publication number
CA2883002C
CA2883002C CA2883002A CA2883002A CA2883002C CA 2883002 C CA2883002 C CA 2883002C CA 2883002 A CA2883002 A CA 2883002A CA 2883002 A CA2883002 A CA 2883002A CA 2883002 C CA2883002 C CA 2883002C
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Prior art keywords
composition
compositions
eye
integer
range
Prior art date
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Application number
CA2883002A
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English (en)
French (fr)
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CA2883002A1 (en
Inventor
Bernhard Gunther
Bastian Theisinger
Sonja Theisinger
Dieter Scherer
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Novaliq GmbH
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Novaliq GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novaliq GmbH filed Critical Novaliq GmbH
Priority to CA2997744A priority Critical patent/CA2997744C/en
Publication of CA2883002A1 publication Critical patent/CA2883002A1/en
Application granted granted Critical
Publication of CA2883002C publication Critical patent/CA2883002C/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA2883002A 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes Active CA2883002C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2997744A CA2997744C (en) 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12183997 2012-09-12
EP12183997.1 2012-09-12
PCT/EP2013/068882 WO2014041055A1 (en) 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2997744A Division CA2997744C (en) 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes

Publications (2)

Publication Number Publication Date
CA2883002A1 CA2883002A1 (en) 2014-03-20
CA2883002C true CA2883002C (en) 2019-05-21

Family

ID=46832270

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2883002A Active CA2883002C (en) 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes
CA2997744A Active CA2997744C (en) 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2997744A Active CA2997744C (en) 2012-09-12 2013-09-12 Compositions comprising mixtures of semifluorinated alkanes

Country Status (13)

Country Link
US (4) US10449164B2 (enExample)
EP (2) EP3100722B1 (enExample)
JP (3) JP6352266B2 (enExample)
KR (2) KR102158400B1 (enExample)
CN (7) CN113679697A (enExample)
AU (3) AU2013314370B2 (enExample)
BR (1) BR112015004997B1 (enExample)
CA (2) CA2883002C (enExample)
DE (1) DE202013012742U1 (enExample)
ES (2) ES2770398T3 (enExample)
MX (2) MX360469B (enExample)
MY (1) MY166228A (enExample)
WO (1) WO2014041055A1 (enExample)

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EP3192501B1 (en) 2011-05-25 2020-05-13 Novaliq GmbH Topical pharmaceutical composition based on semifluorinated alkanes
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WO2013110621A1 (en) 2012-01-23 2013-08-01 Novaliq Gmbh Stabilised protein compositions based on semifluorinated alkanes
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JP6039152B2 (ja) 2012-09-12 2016-12-07 ノバリック ゲーエムベーハー 半フッ素化アルカン組成物
CN114028560A (zh) 2013-07-23 2022-02-11 诺瓦利克有限责任公司 稳定的抗体组合物
WO2017055453A1 (en) * 2015-09-30 2017-04-06 Novaliq Gmbh Semifluorinated compounds for ophthalmic administration
CN110403923B (zh) 2015-09-30 2021-09-21 诺瓦利克有限责任公司 半氟化化合物和其组合物
PT3442480T (pt) 2016-06-23 2019-12-23 Novaliq Gmbh Método de administração tópica
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EP3515420B1 (en) * 2016-09-22 2023-11-08 Novaliq GmbH Pharmaceutical compositions for use in the therapy of blepharitis
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EP3698785A1 (en) * 2016-09-28 2020-08-26 Novaliq GmbH Compositions comprising a cannabinoid receptor binding ligand
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CN120022260A (zh) 2017-10-04 2025-05-23 诺瓦利克有限责任公司 包含f6h8的眼用组合物
KR20200128407A (ko) 2018-03-02 2020-11-12 노바리크 게엠베하 네비볼롤을 포함하는 약제학적 조성물
CN112153970A (zh) 2018-04-27 2020-12-29 诺瓦利克有限责任公司 用于治疗青光眼的包含他氟前列素的眼用组合物
KR20210080388A (ko) 2018-09-22 2021-06-30 노바리크 게엠베하 안구 표면 손상 및 건조 증상 치료를 위한 안약 조성물
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