CA2876062C - Effervescent dosage form - Google Patents

Effervescent dosage form Download PDF

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Publication number
CA2876062C
CA2876062C CA2876062A CA2876062A CA2876062C CA 2876062 C CA2876062 C CA 2876062C CA 2876062 A CA2876062 A CA 2876062A CA 2876062 A CA2876062 A CA 2876062A CA 2876062 C CA2876062 C CA 2876062C
Authority
CA
Canada
Prior art keywords
dosage form
effervescent
chewable dosage
another example
effervescent chewable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2876062A
Other languages
English (en)
French (fr)
Other versions
CA2876062A1 (en
Inventor
Mark Edward Stella
John Richard Entwisle
Jason William Newlon
Christine Louie Naykki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of CA2876062A1 publication Critical patent/CA2876062A1/en
Application granted granted Critical
Publication of CA2876062C publication Critical patent/CA2876062C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/695—Silicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/2036—Silicones; Polysiloxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
CA2876062A 2012-06-12 2013-06-12 Effervescent dosage form Active CA2876062C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261658430P 2012-06-12 2012-06-12
US61/658,430 2012-06-12
PCT/US2013/045303 WO2013188483A1 (en) 2012-06-12 2013-06-12 Effervescent dosage form

Publications (2)

Publication Number Publication Date
CA2876062A1 CA2876062A1 (en) 2013-12-19
CA2876062C true CA2876062C (en) 2017-09-12

Family

ID=48672843

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2876062A Active CA2876062C (en) 2012-06-12 2013-06-12 Effervescent dosage form

Country Status (12)

Country Link
US (1) US10617714B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP2734192B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN104363897A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2013274378B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR112014030680B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2876062C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2541723T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2014DN10385A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX368363B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL2734192T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2014149581A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2013188483A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2604124A1 (en) * 2011-12-16 2013-06-19 Nestec S.A. Soluble non-dairy creamer tablet surface-treated with carbohydrate
AU2016285446A1 (en) * 2015-06-29 2018-01-18 Elc Management Llc Particles with cross-linked coatings for cosmetic applications
CN107114795A (zh) * 2017-07-06 2017-09-01 胥永贵 一种弱碱补钙、苏打碱化姜制剂及其制备方法和应用
US11793876B2 (en) 2019-10-18 2023-10-24 L. Perrigo Company Bulk polyethylene glycol compositions
WO2022060310A1 (en) * 2020-09-18 2022-03-24 Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A.Ş. Pharmaceutical compositions comprising calcium carbonate, magnesium carbonat and simethicone
BR112023026531A2 (pt) * 2021-06-17 2024-03-05 Ocean Spray Cranberries Inc Açúcares raros em alimentos e bebidas
US12053484B2 (en) 2021-10-29 2024-08-06 Medicated Chews, Llc Simethicone chewable composition

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1518364A (en) 1976-05-05 1978-07-19 Beecham Group Ltd Pharmaceutical composition
US4198390A (en) 1979-01-31 1980-04-15 Rider Joseph A Simethicone antacid tablet
US4396604A (en) 1982-05-17 1983-08-02 Norcliff Thayer, Inc. Simethicone antacid lozenge
SE462014B (sv) 1983-09-28 1990-04-30 Gerhard Gergely Brusgranulat och foerfarande foer dess framstaellning
US4678661A (en) * 1983-09-28 1987-07-07 Gerhard Gergely Effervescent composition and method of making same
US4650669A (en) 1985-07-30 1987-03-17 Miles Laboratories, Inc. Method to make effervescent calcium tablets and calcium tablets produced thereby
GB8909793D0 (en) 1989-04-28 1989-06-14 Beecham Group Plc Pharmaceutical formulation
US5073384A (en) 1989-10-19 1991-12-17 Valentine Enterprises, Inc. Maltodextrin/defoaming composition combinate
DE59203732D1 (de) 1991-07-01 1995-10-26 Gergely Gerhard Lutsch- oder Kautablette.
WO1994000107A1 (en) 1992-06-30 1994-01-06 The Procter & Gamble Company Effervescent calcium supplements
US5330760A (en) * 1992-08-27 1994-07-19 Sterling Winthrop Inc. Effervescent antacid
FR2705966B1 (fr) 1993-06-04 1995-08-25 Dow Corning Sa Compositions antimousse utiles notamment pour le traitement de troubles gastriques.
EP0804171B1 (de) 1995-07-31 2000-01-05 Gergely, Gerhard, Dr. Kautablette mit brausewirkung
CA2204599A1 (en) 1995-09-07 1997-03-13 Otsuka Pharmaceutical Co., Ltd. Low-pressure tableted effervescent preparation
US5807577A (en) 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5888544A (en) 1996-06-20 1999-03-30 Gerhard Gergely Effervescent system for effervescent tablets and effervescent granules
DE19814256A1 (de) 1998-03-31 1999-10-07 Asta Medica Ag Feste, schnellzerfallende Cetirizin-Formulierungen
GB9825033D0 (en) 1998-11-13 1999-01-13 Nycomed Pharma As Process
US6296868B1 (en) 1998-11-19 2001-10-02 Advanced Technology Pharmaceuticals Corporation Chewable tablets containing mannitol and aspartame
DE19859231A1 (de) 1998-12-21 2000-06-29 Kurt Heinz Bauer Schäumende Antacida-Suspensionstabletten
US6589555B2 (en) 1999-12-29 2003-07-08 Mahendra Pandya Effervescent vitaceutical compositions and related methods
US6544557B2 (en) 2001-01-09 2003-04-08 Pan Pharmaceutical Limited Effervescent tablet compositions
US20030235613A1 (en) 2002-06-19 2003-12-25 Cts Chemical Industries Ltd. Popping oral administration form
US20040223921A1 (en) 2003-05-07 2004-11-11 Rau Allen H. Oral care tablet
US20050074489A1 (en) 2003-10-01 2005-04-07 Pediamed Pharmaceuticals, Inc. Effervescent and effervescent-dispersion compositions for medicaments and methods of use thereof
ITMI20040242U1 (it) 2004-05-24 2004-08-24 Istituto Pirri S R L Contenitore per compresse effervescenti
WO2006044595A2 (en) 2004-10-13 2006-04-27 Cadbury Adams Usa Llc Effervescent pressed gum tablet compositions
US20090004248A1 (en) 2007-06-29 2009-01-01 Frank Bunick Dual portion dosage lozenge form
EP2189154A1 (en) 2008-11-25 2010-05-26 Gnosis S.p.A. Effervescent tablets and mouth-soluble granulates of S-adenosyl methionine and process for the preparation thereof
CN101966165B (zh) 2009-07-14 2012-06-13 无锡健而乐医药科技有限公司 口腔吸收固体泡腾制剂
WO2011113965A1 (es) 2010-03-18 2011-09-22 Farmalider, S.A. Composición farmacéutica en forma sólida que contiene isoflavonas, una sal de calcio y vitamina d3
CN102232967A (zh) * 2010-04-21 2011-11-09 武汉同济现代医药有限公司 一种新型口服补钙泡腾剂及其制备方法
US20140371174A1 (en) 2013-06-12 2014-12-18 The Procter & Gamble Company Effervescent Dosage Form

Also Published As

Publication number Publication date
EP2734192A1 (en) 2014-05-28
RU2014149581A (ru) 2016-07-10
US20190262392A1 (en) 2019-08-29
BR112014030680B1 (pt) 2022-08-30
MX2014015253A (es) 2015-03-05
IN2014DN10385A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-08-14
ES2541723T3 (es) 2015-07-24
US10617714B2 (en) 2020-04-14
BR112014030680A2 (pt) 2017-06-27
WO2013188483A1 (en) 2013-12-19
CN104363897A (zh) 2015-02-18
PL2734192T3 (pl) 2015-09-30
EP2734192B1 (en) 2015-04-15
AU2013274378B2 (en) 2016-06-02
CA2876062A1 (en) 2013-12-19
MX368363B (es) 2019-09-30
AU2013274378A1 (en) 2015-01-15

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Effective date: 20141208