RU2014149581A - Шипучая лекарственная форма - Google Patents
Шипучая лекарственная форма Download PDFInfo
- Publication number
- RU2014149581A RU2014149581A RU2014149581A RU2014149581A RU2014149581A RU 2014149581 A RU2014149581 A RU 2014149581A RU 2014149581 A RU2014149581 A RU 2014149581A RU 2014149581 A RU2014149581 A RU 2014149581A RU 2014149581 A RU2014149581 A RU 2014149581A
- Authority
- RU
- Russia
- Prior art keywords
- dosage form
- effervescent
- chewable dosage
- form according
- effervescent chewable
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 title claims abstract 32
- 239000003795 chemical substances by application Substances 0.000 claims abstract 13
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract 9
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical group [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract 8
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical group [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract 6
- 230000003472 neutralizing effect Effects 0.000 claims abstract 6
- 239000002253 acid Substances 0.000 claims abstract 5
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract 4
- 235000003599 food sweetener Nutrition 0.000 claims abstract 4
- 239000003765 sweetening agent Substances 0.000 claims abstract 4
- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 claims abstract 3
- 229940083037 simethicone Drugs 0.000 claims abstract 3
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract 3
- 235000017557 sodium bicarbonate Nutrition 0.000 claims abstract 3
- 230000001066 destructive effect Effects 0.000 claims abstract 2
- 239000000314 lubricant Substances 0.000 claims abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000003826 tablet Substances 0.000 claims 2
- 241000167854 Bourreria succulenta Species 0.000 claims 1
- 244000248349 Citrus limon Species 0.000 claims 1
- 235000005979 Citrus limon Nutrition 0.000 claims 1
- 239000004376 Sucralose Substances 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- 235000019693 cherries Nutrition 0.000 claims 1
- 239000007910 chewable tablet Substances 0.000 claims 1
- 229940068682 chewable tablet Drugs 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims 1
- 235000019408 sucralose Nutrition 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 230000001055 chewing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/2036—Silicones; Polysiloxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261658430P | 2012-06-12 | 2012-06-12 | |
US61/658,430 | 2012-06-12 | ||
PCT/US2013/045303 WO2013188483A1 (en) | 2012-06-12 | 2013-06-12 | Effervescent dosage form |
Publications (1)
Publication Number | Publication Date |
---|---|
RU2014149581A true RU2014149581A (ru) | 2016-07-10 |
Family
ID=48672843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2014149581A RU2014149581A (ru) | 2012-06-12 | 2013-06-12 | Шипучая лекарственная форма |
Country Status (12)
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2604124A1 (en) * | 2011-12-16 | 2013-06-19 | Nestec S.A. | Soluble non-dairy creamer tablet surface-treated with carbohydrate |
AU2016285446A1 (en) * | 2015-06-29 | 2018-01-18 | Elc Management Llc | Particles with cross-linked coatings for cosmetic applications |
CN107114795A (zh) * | 2017-07-06 | 2017-09-01 | 胥永贵 | 一种弱碱补钙、苏打碱化姜制剂及其制备方法和应用 |
US11793876B2 (en) | 2019-10-18 | 2023-10-24 | L. Perrigo Company | Bulk polyethylene glycol compositions |
WO2022060310A1 (en) * | 2020-09-18 | 2022-03-24 | Pharmacti̇ve İlaç Sanayi̇ Ve Ti̇caret A.Ş. | Pharmaceutical compositions comprising calcium carbonate, magnesium carbonat and simethicone |
BR112023026531A2 (pt) * | 2021-06-17 | 2024-03-05 | Ocean Spray Cranberries Inc | Açúcares raros em alimentos e bebidas |
US12053484B2 (en) | 2021-10-29 | 2024-08-06 | Medicated Chews, Llc | Simethicone chewable composition |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1518364A (en) | 1976-05-05 | 1978-07-19 | Beecham Group Ltd | Pharmaceutical composition |
US4198390A (en) | 1979-01-31 | 1980-04-15 | Rider Joseph A | Simethicone antacid tablet |
US4396604A (en) | 1982-05-17 | 1983-08-02 | Norcliff Thayer, Inc. | Simethicone antacid lozenge |
SE462014B (sv) | 1983-09-28 | 1990-04-30 | Gerhard Gergely | Brusgranulat och foerfarande foer dess framstaellning |
US4678661A (en) * | 1983-09-28 | 1987-07-07 | Gerhard Gergely | Effervescent composition and method of making same |
US4650669A (en) | 1985-07-30 | 1987-03-17 | Miles Laboratories, Inc. | Method to make effervescent calcium tablets and calcium tablets produced thereby |
GB8909793D0 (en) | 1989-04-28 | 1989-06-14 | Beecham Group Plc | Pharmaceutical formulation |
US5073384A (en) | 1989-10-19 | 1991-12-17 | Valentine Enterprises, Inc. | Maltodextrin/defoaming composition combinate |
DE59203732D1 (de) | 1991-07-01 | 1995-10-26 | Gergely Gerhard | Lutsch- oder Kautablette. |
WO1994000107A1 (en) | 1992-06-30 | 1994-01-06 | The Procter & Gamble Company | Effervescent calcium supplements |
US5330760A (en) * | 1992-08-27 | 1994-07-19 | Sterling Winthrop Inc. | Effervescent antacid |
FR2705966B1 (fr) | 1993-06-04 | 1995-08-25 | Dow Corning Sa | Compositions antimousse utiles notamment pour le traitement de troubles gastriques. |
EP0804171B1 (de) | 1995-07-31 | 2000-01-05 | Gergely, Gerhard, Dr. | Kautablette mit brausewirkung |
CA2204599A1 (en) | 1995-09-07 | 1997-03-13 | Otsuka Pharmaceutical Co., Ltd. | Low-pressure tableted effervescent preparation |
US5807577A (en) | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5888544A (en) | 1996-06-20 | 1999-03-30 | Gerhard Gergely | Effervescent system for effervescent tablets and effervescent granules |
DE19814256A1 (de) | 1998-03-31 | 1999-10-07 | Asta Medica Ag | Feste, schnellzerfallende Cetirizin-Formulierungen |
GB9825033D0 (en) | 1998-11-13 | 1999-01-13 | Nycomed Pharma As | Process |
US6296868B1 (en) | 1998-11-19 | 2001-10-02 | Advanced Technology Pharmaceuticals Corporation | Chewable tablets containing mannitol and aspartame |
DE19859231A1 (de) | 1998-12-21 | 2000-06-29 | Kurt Heinz Bauer | Schäumende Antacida-Suspensionstabletten |
US6589555B2 (en) | 1999-12-29 | 2003-07-08 | Mahendra Pandya | Effervescent vitaceutical compositions and related methods |
US6544557B2 (en) | 2001-01-09 | 2003-04-08 | Pan Pharmaceutical Limited | Effervescent tablet compositions |
US20030235613A1 (en) | 2002-06-19 | 2003-12-25 | Cts Chemical Industries Ltd. | Popping oral administration form |
US20040223921A1 (en) | 2003-05-07 | 2004-11-11 | Rau Allen H. | Oral care tablet |
US20050074489A1 (en) | 2003-10-01 | 2005-04-07 | Pediamed Pharmaceuticals, Inc. | Effervescent and effervescent-dispersion compositions for medicaments and methods of use thereof |
ITMI20040242U1 (it) | 2004-05-24 | 2004-08-24 | Istituto Pirri S R L | Contenitore per compresse effervescenti |
WO2006044595A2 (en) | 2004-10-13 | 2006-04-27 | Cadbury Adams Usa Llc | Effervescent pressed gum tablet compositions |
US20090004248A1 (en) | 2007-06-29 | 2009-01-01 | Frank Bunick | Dual portion dosage lozenge form |
EP2189154A1 (en) | 2008-11-25 | 2010-05-26 | Gnosis S.p.A. | Effervescent tablets and mouth-soluble granulates of S-adenosyl methionine and process for the preparation thereof |
CN101966165B (zh) | 2009-07-14 | 2012-06-13 | 无锡健而乐医药科技有限公司 | 口腔吸收固体泡腾制剂 |
WO2011113965A1 (es) | 2010-03-18 | 2011-09-22 | Farmalider, S.A. | Composición farmacéutica en forma sólida que contiene isoflavonas, una sal de calcio y vitamina d3 |
CN102232967A (zh) * | 2010-04-21 | 2011-11-09 | 武汉同济现代医药有限公司 | 一种新型口服补钙泡腾剂及其制备方法 |
US20140371174A1 (en) | 2013-06-12 | 2014-12-18 | The Procter & Gamble Company | Effervescent Dosage Form |
-
2013
- 2013-06-12 IN IN10385DEN2014 patent/IN2014DN10385A/en unknown
- 2013-06-12 CN CN201380031083.4A patent/CN104363897A/zh active Pending
- 2013-06-12 RU RU2014149581A patent/RU2014149581A/ru unknown
- 2013-06-12 WO PCT/US2013/045303 patent/WO2013188483A1/en active Application Filing
- 2013-06-12 MX MX2014015253A patent/MX368363B/es active IP Right Grant
- 2013-06-12 PL PL13731013T patent/PL2734192T3/pl unknown
- 2013-06-12 BR BR112014030680-0A patent/BR112014030680B1/pt active IP Right Grant
- 2013-06-12 CA CA2876062A patent/CA2876062C/en active Active
- 2013-06-12 AU AU2013274378A patent/AU2013274378B2/en active Active
- 2013-06-12 EP EP13731013.2A patent/EP2734192B1/en active Active
- 2013-06-12 ES ES13731013.2T patent/ES2541723T3/es active Active
-
2019
- 2019-05-09 US US16/407,268 patent/US10617714B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2876062C (en) | 2017-09-12 |
EP2734192A1 (en) | 2014-05-28 |
US20190262392A1 (en) | 2019-08-29 |
BR112014030680B1 (pt) | 2022-08-30 |
MX2014015253A (es) | 2015-03-05 |
IN2014DN10385A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-08-14 |
ES2541723T3 (es) | 2015-07-24 |
US10617714B2 (en) | 2020-04-14 |
BR112014030680A2 (pt) | 2017-06-27 |
WO2013188483A1 (en) | 2013-12-19 |
CN104363897A (zh) | 2015-02-18 |
PL2734192T3 (pl) | 2015-09-30 |
EP2734192B1 (en) | 2015-04-15 |
AU2013274378B2 (en) | 2016-06-02 |
CA2876062A1 (en) | 2013-12-19 |
MX368363B (es) | 2019-09-30 |
AU2013274378A1 (en) | 2015-01-15 |
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