CA2871314A1 - Procede de preparation de steroides 17-substitues - Google Patents

Procede de preparation de steroides 17-substitues Download PDF

Info

Publication number
CA2871314A1
CA2871314A1 CA2871314A CA2871314A CA2871314A1 CA 2871314 A1 CA2871314 A1 CA 2871314A1 CA 2871314 A CA2871314 A CA 2871314A CA 2871314 A CA2871314 A CA 2871314A CA 2871314 A1 CA2871314 A1 CA 2871314A1
Authority
CA
Canada
Prior art keywords
compound
formula
process according
group
protecting group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2871314A
Other languages
English (en)
Inventor
Erwin Schreiner
Craig E. Dixon
Boris Gorin
Qingbo LU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alphora Research Inc
Original Assignee
Alphora Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alphora Research Inc filed Critical Alphora Research Inc
Publication of CA2871314A1 publication Critical patent/CA2871314A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
CA2871314A 2012-04-23 2013-04-22 Procede de preparation de steroides 17-substitues Abandoned CA2871314A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261637048P 2012-04-23 2012-04-23
US61/637,048 2012-04-23
US201261642253P 2012-05-03 2012-05-03
US61/642,253 2012-05-03
PCT/CA2013/050311 WO2013159225A1 (fr) 2012-04-23 2013-04-22 Procédé de préparation de stéroïdes 17-substitués

Publications (1)

Publication Number Publication Date
CA2871314A1 true CA2871314A1 (fr) 2013-10-31

Family

ID=49482082

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2871314A Abandoned CA2871314A1 (fr) 2012-04-23 2013-04-22 Procede de preparation de steroides 17-substitues

Country Status (3)

Country Link
EP (1) EP2841444A4 (fr)
CA (1) CA2871314A1 (fr)
WO (1) WO2013159225A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2877482A4 (fr) * 2012-07-25 2016-04-06 Mapi Pharma Ltd Procédé et intermédiaires utilisés pour la préparation de l'acétate d'abiratérone
US9937259B2 (en) * 2014-06-27 2018-04-10 Zhuhai Beihai Biotech Co., Ltd. Abiraterone derivatives and non-covalent complexes with albumin
WO2016162229A1 (fr) 2015-04-10 2016-10-13 Capsugel Belgium N.V. Formulations lipidiques d'acétate d'abiratérone
CN105503992A (zh) * 2016-01-22 2016-04-20 江苏联环药业股份有限公司 一种醋酸阿比特龙的制备方法
CN107722101A (zh) * 2017-11-03 2018-02-23 郑州大学 甾体吡啶类衍生物及其制备方法和应用
WO2020180942A1 (fr) 2019-03-06 2020-09-10 Propella Therapeutics, Inc. Promédicaments d'abiratérone
US11957696B2 (en) 2021-02-15 2024-04-16 Propella Therapeutics, Inc. Abiraterone prodrugs

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2938030A (en) * 1956-10-03 1960-05-24 Ciba Pharm Prod Inc New steroids substituted by a heterocyclic nitrogen-containing ring in 17-position
NZ249911A (en) * 1992-03-31 1996-06-25 British Tech Group 17-(3-pyridyl) substituted steroids and use in pharmaceutical compositions
ATE176481T1 (de) * 1993-09-30 1999-02-15 Btg Int Ltd Synthese von 17-(3-pyridyl) steroiden
CN101768199B (zh) * 2009-12-24 2014-03-26 深圳万乐药业有限公司 醋酸阿比特龙的多晶型物及其制备方法
CN102321142A (zh) * 2011-09-29 2012-01-18 重庆医药工业研究院有限责任公司 一种醋酸阿比特龙晶型及其制备方法
EP2607371A1 (fr) * 2011-12-23 2013-06-26 Crystal Pharma, S.A.U. Procédés de préparation d'abiratérone et composés associés
EP2877482A4 (fr) * 2012-07-25 2016-04-06 Mapi Pharma Ltd Procédé et intermédiaires utilisés pour la préparation de l'acétate d'abiratérone
CN102898495B (zh) * 2012-11-12 2014-11-26 浙江神洲药业有限公司 醋酸阿比特龙酯的制备方法

Also Published As

Publication number Publication date
EP2841444A4 (fr) 2015-11-04
EP2841444A1 (fr) 2015-03-04
WO2013159225A1 (fr) 2013-10-31

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20190423