CA2864489C - Use of the cd2 signaling domain in second-generation chimeric antigen receptors - Google Patents
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| DK2958943T3 (da) | 2013-02-20 | 2019-12-09 | Univ Pennsylvania | Behandling af cancer ved anvendelse af humaniseret anti-EGFRvIII kimær antigenreceptor |
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| WO2014055442A2 (en) * | 2012-10-01 | 2014-04-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for targeting stromal cells for the treatment of cancer |
| EP2903637B1 (en) * | 2012-10-02 | 2019-06-12 | Memorial Sloan-Kettering Cancer Center | Compositions and methods for immunotherapy |
| CN107109419B (zh) * | 2014-07-21 | 2020-12-22 | 诺华股份有限公司 | 使用cd33嵌合抗原受体治疗癌症 |
| SG11201700770PA (en) * | 2014-08-19 | 2017-03-30 | Novartis Ag | Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment |
| WO2016036973A1 (en) * | 2014-09-04 | 2016-03-10 | The Trustees Of The University Of Pennsylvania | Glypican-3 antibody and uses thereof |
| US20180334490A1 (en) * | 2014-12-03 | 2018-11-22 | Qilong H. Wu | Methods for b cell preconditioning in car therapy |
| AU2017225733A1 (en) * | 2016-03-04 | 2018-09-27 | Novartis Ag | Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore |
| RU2019105693A (ru) * | 2016-08-01 | 2020-09-01 | Новартис Аг | Лечение рака с применением химерного антигенного рецептора в комбинации с ингибитором молекулы, способствующей фенотипу m2 макрофага |
| WO2019210207A2 (en) * | 2018-04-27 | 2019-10-31 | The Trustees Of The University Of Pennsylvania | Chimeric antigen receptor t regulatory cells for the treatment of atherosclerosis |
| EP3856779A1 (en) * | 2018-09-28 | 2021-08-04 | Novartis AG | Cd22 chimeric antigen receptor (car) therapies |
| EP3856782A1 (en) * | 2018-09-28 | 2021-08-04 | Novartis AG | Cd19 chimeric antigen receptor (car) and cd22 car combination therapies |
| JP7620374B2 (ja) * | 2018-12-19 | 2025-01-23 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Ｔ細胞リンパ腫およびｔ細胞白血病に対するｃｄ２／５／７ノックアウト抗ｃｄ２／５／７キメラ抗原受容体ｔ細胞の使用 |
| TW202042824A (zh) * | 2019-03-27 | 2020-12-01 | 賓夕法尼亞大學董事會 | Tn-MUC1嵌合抗原受體（CAR）T細胞療法 |
| WO2020236964A1 (en) * | 2019-05-20 | 2020-11-26 | The Trustees Of The University Of Pennsylvania | Engineered expression of cell surface and secreted sialidase by car t cells for increased efficacy in solid tumors |
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2013
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- 2013-02-22 JP JP2014558875A patent/JP2015509716A/ja not_active Withdrawn
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- 2013-02-22 EA EA201491573A patent/EA201491573A1/ru unknown
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2014
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| US11597754B2 (en) | 2023-03-07 |
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| SG11201404284SA (en) | 2014-10-30 |
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| US20180037625A1 (en) | 2018-02-08 |
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| US20140370045A1 (en) | 2014-12-18 |
| EP2817331A4 (en) | 2015-09-30 |
| US20210371495A1 (en) | 2021-12-02 |
| US20190352369A1 (en) | 2019-11-21 |
| KR20140127829A (ko) | 2014-11-04 |
| BR112014020502A2 (pt) | 2019-09-24 |
| CA2864489A1 (en) | 2013-08-29 |
| US20230242612A1 (en) | 2023-08-03 |
| CN104136458A (zh) | 2014-11-05 |
| IN2014DN06522A (enExample) | 2015-06-12 |
| EP2817331A1 (en) | 2014-12-31 |
| EP4275699A2 (en) | 2023-11-15 |
| AU2013222284A1 (en) | 2014-08-07 |
| EP2817331B1 (en) | 2023-08-30 |
| EP4275699A3 (en) | 2024-01-03 |
| US9783591B2 (en) | 2017-10-10 |
| WO2013126729A1 (en) | 2013-08-29 |
| IL233993A0 (en) | 2014-09-30 |
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