CA2861258C - Materiau sensible aux stimuli et materiau medical le comprenant - Google Patents
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- CA2861258C CA2861258C CA2861258A CA2861258A CA2861258C CA 2861258 C CA2861258 C CA 2861258C CA 2861258 A CA2861258 A CA 2861258A CA 2861258 A CA2861258 A CA 2861258A CA 2861258 C CA2861258 C CA 2861258C
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- Chemical Kinetics & Catalysis (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Compositions Of Macromolecular Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention concerne un matériau sensible aux stimuli, caractérisé en ce qu'il comprend un polymère sensible aux stimuli, des fibres et de l'eau, les fibres possédant un diamètre moyen en nombre compris entre 1 nm et 900 nm et étant dispersées dans le matériau sensible aux stimuli. L'invention concerne également un matériau médical et un matériau anti-adhérence, chacun comprenant un matériau sensible aux stimuli qui comprend un polymère sensible aux stimuli, des fibres et de l'eau, les fibres possédant un diamètre moyen en nombre compris entre 1 nm et 900 nm et étant dispersées dans le matériau sensible aux stimuli. Le matériau sensible aux stimuli est plus commode à utiliser et présente toutes les propriétés dynamiques demandées quand il est revêtu et les propriétés requises pour diverses applications (par exemple, biodégradation, biocompatibilité, faible toxicité).
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
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JP2012-024674 | 2012-02-08 | ||
JP2012024673 | 2012-02-08 | ||
JP2012-024673 | 2012-02-08 | ||
JP2012024674 | 2012-02-08 | ||
JP2012145164 | 2012-06-28 | ||
JP2012-145164 | 2012-06-28 | ||
JP2012155262 | 2012-07-11 | ||
JP2012-155262 | 2012-07-11 | ||
JP2012155261 | 2012-07-11 | ||
JP2012-155261 | 2012-07-11 | ||
JP2012-229573 | 2012-10-17 | ||
JP2012229573 | 2012-10-17 | ||
PCT/JP2013/051813 WO2013118605A1 (fr) | 2012-02-08 | 2013-01-29 | Matériau sensible aux stimuli et matériau médical le comprenant |
Publications (2)
Publication Number | Publication Date |
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CA2861258A1 CA2861258A1 (fr) | 2013-08-15 |
CA2861258C true CA2861258C (fr) | 2019-08-20 |
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CA2861258A Active CA2861258C (fr) | 2012-02-08 | 2013-01-29 | Materiau sensible aux stimuli et materiau medical le comprenant |
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US (1) | US9616154B2 (fr) |
EP (1) | EP2813531B1 (fr) |
JP (1) | JP6090160B2 (fr) |
CN (1) | CN104093770B (fr) |
CA (1) | CA2861258C (fr) |
ES (1) | ES2706149T3 (fr) |
RU (1) | RU2625761C2 (fr) |
TW (1) | TWI601543B (fr) |
WO (1) | WO2013118605A1 (fr) |
Families Citing this family (5)
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JP6660631B2 (ja) * | 2015-08-10 | 2020-03-11 | ローム株式会社 | 窒化物半導体デバイス |
CN109252289A (zh) * | 2018-08-24 | 2019-01-22 | 合肥工业大学 | 一种响应性聚(n-异丙基丙烯酰胺)/金棒/木纤维复合材料的制备方法 |
EP3946458A4 (fr) * | 2019-04-02 | 2023-01-11 | Cytomatrix Limited | Composition pour l'administration d'agents biologiquement actifs et ses utilisations |
TWI821653B (zh) * | 2021-04-15 | 2023-11-11 | 財團法人紡織產業綜合研究所 | 感溫調濕纖維及其製備方法 |
WO2024058065A1 (fr) * | 2022-09-16 | 2024-03-21 | 慶應義塾 | Système d'administration de médicament de type à induction de chaleur |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0491204B1 (fr) * | 1990-12-05 | 1997-01-15 | Ppg Industries, Inc. | Matériau fibreux thermoplastique formé humide et dispersion aqueuse pour sa préparation |
EP0551626A1 (fr) * | 1991-12-19 | 1993-07-21 | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. | Gel thermoréversible utile comme excipient pharmaceutique pour une formation galénique |
US6117949A (en) | 1998-10-01 | 2000-09-12 | Macromed, Inc. | Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
CN1195788C (zh) | 1997-10-03 | 2005-04-06 | 麦克罗梅德公司 | 具有可逆热胶凝性质的可生物降解低分子量三嵌段聚(丙交酯-共聚-乙交酯)聚乙二醇共聚物 |
JP4217804B2 (ja) | 1998-09-14 | 2009-02-04 | 独立行政法人産業技術総合研究所 | 上限溶液臨界温度を有する熱応答性高分子誘導体を用いた熱応答型分離材料及び薬剤放出カプセル |
JP3584722B2 (ja) | 1998-02-13 | 2004-11-04 | 富士ゼロックス株式会社 | 高分子ゲル組成物、その製造方法及びそれを用いた光学素子 |
US6451346B1 (en) * | 1998-12-23 | 2002-09-17 | Amgen Inc | Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents |
JP2003252936A (ja) | 2002-02-28 | 2003-09-10 | Sentomedo:Kk | 温度応答性材料及びそれを含む組成物 |
AU2003225516A1 (en) * | 2002-03-26 | 2003-10-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Responsive biomedical composites |
JP2004307523A (ja) * | 2003-02-19 | 2004-11-04 | Ajinomoto Co Inc | 温度応答性生分解性ゲル |
KR100506543B1 (ko) * | 2003-08-14 | 2005-08-05 | 주식회사 제닉 | 온도 감응성 상태변화 하이드로겔 조성물 및 그 제조방법 |
US8501642B2 (en) * | 2004-02-19 | 2013-08-06 | Toray Industries, Inc. | Nano-fiber compound solutions, emulsions and gels, production method thereof, Nano-fiber synthetic papers, and production method thereof |
JP5082192B2 (ja) * | 2004-02-19 | 2012-11-28 | 東レ株式会社 | ナノファイバー合成紙の製造方法 |
JP4687163B2 (ja) * | 2004-03-16 | 2011-05-25 | 東レ株式会社 | 配合溶液、乳液またはゲル状物およびその製造方法 |
JP2008029226A (ja) * | 2006-07-27 | 2008-02-14 | Toray Ind Inc | 温度応答性基材および細胞 |
AU2007325001B2 (en) * | 2006-11-30 | 2014-04-10 | Smith & Nephew, Inc. | Fiber reinforced composite material |
JP5171146B2 (ja) | 2007-07-27 | 2013-03-27 | 学校法人 関西大学 | 温度応答性を有する生分解性ポリマー及びその製造方法 |
US8683798B2 (en) * | 2010-01-15 | 2014-04-01 | Syracuse University | Stimuli-responsive product |
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2013
- 2013-01-29 RU RU2014136336A patent/RU2625761C2/ru active
- 2013-01-29 CA CA2861258A patent/CA2861258C/fr active Active
- 2013-01-29 WO PCT/JP2013/051813 patent/WO2013118605A1/fr active Application Filing
- 2013-01-29 US US14/377,051 patent/US9616154B2/en active Active
- 2013-01-29 EP EP13746253.7A patent/EP2813531B1/fr active Active
- 2013-01-29 CN CN201380008701.3A patent/CN104093770B/zh active Active
- 2013-01-29 ES ES13746253T patent/ES2706149T3/es active Active
- 2013-01-29 JP JP2013510430A patent/JP6090160B2/ja active Active
- 2013-02-07 TW TW102104808A patent/TWI601543B/zh active
Also Published As
Publication number | Publication date |
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JPWO2013118605A1 (ja) | 2015-05-11 |
TW201336530A (zh) | 2013-09-16 |
JP6090160B2 (ja) | 2017-03-08 |
CA2861258A1 (fr) | 2013-08-15 |
US20150005409A1 (en) | 2015-01-01 |
RU2014136336A (ru) | 2016-04-10 |
ES2706149T3 (es) | 2019-03-27 |
RU2625761C2 (ru) | 2017-07-18 |
EP2813531A1 (fr) | 2014-12-17 |
EP2813531A4 (fr) | 2015-08-26 |
CN104093770A (zh) | 2014-10-08 |
TWI601543B (zh) | 2017-10-11 |
US9616154B2 (en) | 2017-04-11 |
EP2813531B1 (fr) | 2018-11-21 |
WO2013118605A1 (fr) | 2013-08-15 |
CN104093770B (zh) | 2017-12-26 |
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